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National study on the utilization of prophylactic antibiotics in surgery, Belgium, 1986

Published online by Cambridge University Press:  15 May 2009

R. Mertens ,
L. Verbist ,
B. Gordts ,
S. Lauwers ,
C. Potvliege ,
G. Reybrouck ,
G. Verschraegen ,
G. Wauters ,
L. Berghmans  and
F. Dondeyne
...Show all authors
R. Mertens*
Affiliation:
Epidemiology Unit, Institute of Hygiene and Epidemiology, Brussels
L. Verbist
Affiliation:
Clinical Bacteriology Laboratory, U.Z. St-Rafaël, Katholieke Universiteit Leuven
B. Gordts
Affiliation:
Microbiology Laboratory, A.Z. St-Jan, Brugge
S. Lauwers
Affiliation:
Microbiology Department, A.Z., Vrije Universiteit Brussels
C. Potvliege
Affiliation:
Microbiology Laboratory, Centre Hospitalier Universitaire Tivoli, La Louvière
G. Reybrouck
Affiliation:
Hygiene Laboratory, School of Public Health, Katholieke Universiteit Leuven
G. Verschraegen
Affiliation:
Bacteriology and Virology Department, Rijksuniversiteit Gent
G. Wauters
Affiliation:
Microbiology Department, Université Catholique de Louvain, Brussels
L. Berghmans
Affiliation:
Service Hygiène et Prévention, Ministère de la Communauté Française, Brussels
F. Dondeyne
Affiliation:
Hygiëne en Gezondheidsinspectie, Ministerie van de Vlaamse Gemeenschap, Brussels
A. Stroobant
Affiliation:
Epidemiology Unit, Institute of Hygiene and Epidemiology, Brussels
*
Dr R. Mertens, Epidemiology Unit, Institute of Hygiene and Epidemiology, Wytsmanstr. 14, 1050 Brussels.
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During the last week of May 1986, a 1-week prospective study on antibiotic utilization in surgical patients was held in 104 (42%) of the 247 Belgian acute care hospitals. All surgical patients with a post-operative stay of at least 3 days were studied, involving 3112 patients. Each patient was observed for 7 days, starting from the day before surgery. Antibiotics were administered to 71·9% of all patients; 21·9% received therapeutic antibiotics and 52·9% prophylactic antibiotics; 2·9% received both. Of the 1285 patients undergoing a surgical procedure with no indication for antimicrobial prophylaxis, 50·7% nevertheless received prophylaxis; 92·8% of patients with a generally recognized indication for prophylaxis received antibiotic prophylaxis. Less than one fifth (17·1 %) of all prophylactic courses were stopped on the day of the intervention whilst 26·3% were continued up to the fifth post-operative day or beyond. The most frequently prescribed drugs for this indication included first and second generation cephalosporins and nitroimidazoles. The number of different generic drugs utilized per hospital ranged from 1 to 18 (mean: 7·7).

Type
Research Article
Information
Epidemiology & Infection , Volume 103 , Issue 2 , October 1989 , pp. 311 - 322
Copyright
Copyright © Cambridge University Press 1989

References

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