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A morphological comparison of Bittner and influenza viruses*

Published online by Cambridge University Press:  15 May 2009

June D. Almeida ,
A. P. Waterson  and
J. Anne Drewe
June D. Almeida
Affiliation:
Department of Medical Microbiology, St Thomas's Hospital Medical School, London, S.E. 1
A. P. Waterson
Affiliation:
Department of Medical Microbiology, St Thomas's Hospital Medical School, London, S.E. 1
J. Anne Drewe
Affiliation:
Department of Mycology, Charing Cross Hospital Medical School, Fulham Hospital, London, W. 6
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By the negative staining technique both Bittner and influenza viruses are pleomorphic and have similar fringed surfaces. The present study revealed that Bittner virus had one characteristic form consisting of a head approximately 1000 Å. in diameter and a tail up to 3000 Å. long. On storage at −20° C. Bittner virus broke down to reveal a round internal component of 750 Å. diameter. Influenza virus did not break down on storage at −20° C. but a small number of spontaneously disrupted particles revealed that the internal component was in the form of a coil. The circular internal component of Bittner virus is presumed to be spherical and corresponds to the previously described type A particles as seen by negative staining. The complete enveloped particle corresponds to the type B particle of thin sectioning. It is suggested that the thinly sectioned mature type B particle may be a degenerate form of the so-called immature type B particle. In addition, it is suggested that certain murine RNA tumour viruses may have a morphology distinctive to them.

Type
Research Article
Information
Journal of Hygiene , Volume 65 , Issue 4 , December 1967 , pp. 467 - 474
Copyright
Copyright © Cambridge University Press 1967

References

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