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Human poxvirus infection after the eradication of smallpox

Published online by Cambridge University Press:  19 October 2009

Derrick Baxby
Derrick Baxby
Affiliation:
University Department of Medical Microbiology, Royal Liverpool Hospital, Prescot Street, Liverpool L7 8XW, UK
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There occurred during the planning and publication of this review: the twentieth anniversary of the start of the intensified WHO Smallpox Eradication Campaign and the tenth anniversary of the last endemic case of smallpox; debate about the fate of smallpox virus and possibly its irrevocable destruction; claims that mass smallpox vaccination campaigns may have helped the spread of AIDS in Africa; publication of the definitive account of Smallpox and its Eradication (Fenner et al. 1988), and the closure of the WHO Smallpox Eradication Unit (SEU). It is therefore perhaps an appropriate moment to assess the current status of human poxvirus infections and their epidemiology; this review concentrates on those viruses antigenically related to smallpox (i.e. orthopoxviruses).

Type
Special Article
Information
Epidemiology & Infection , Volume 100 , Issue 3 , June 1988 , pp. 321 - 334
Copyright
Copyright © Cambridge University Press 1988

References

Arita, I., Gispen, R., Kalter, S. S., Wah, L. T., Marennikova, S. S., Netter, R. & Tagaya, I. (1972). Outbreaks of monkeypox and serological surveys in non-human primates. Bulletin of the World Health Organization 46, 625–631.Google Scholar
Arita, I. & Gromyko, A. (1982). Surveillance of orthopoxvirus infections, and associated research, in the period after smallpox eradication. Bulletin of the World Health Organization 60, 367–375.Google ScholarPubMed
Arita, I., Jezek, Z., Khodakevich, L. & Ruti, K. (1985). Human monkeypox: a newly emerged orthopoxvirus zoonosis in the tropical rain forests of Africa. American Journal of Tropical Medicine and Hygiene 34, 781–789.CrossRefGoogle ScholarPubMed
Baxby, D. (1977 a). Poxvirus hosts and reservoirs. Archives of Virology 55, 169–179.CrossRefGoogle ScholarPubMed
Baxby, D. (1977 b). Is cowpox misnamed? a review of ten human cases. British Medical Journal i, 1379–1381.CrossRefGoogle Scholar
Baxby, D. (1987). The conservation of smallpox virus. Lancet ii, 1211–1212.CrossRefGoogle Scholar
Baxby, D. (1988). Poxvirus infections in domestic animals. In Virus Diseases in Laboratory and Captive Animals (ed. Darai, G.), pp. 17–35. Boston: M. Nijhoff.CrossRefGoogle Scholar
Baxby, D. & Ghaboosi, B. (1977). Laboratory characteristics of poxviruses isolated from captive elephants in Germany. Journal of General Virology 37, 407–414.CrossRefGoogle ScholarPubMed
Baxby, D., Shackleton, B., Wheeler, J. & Turner, A. (1979). Comparison of cowpox-like viruses isolated from European zoos. Archives of Virology 61, 337–340.CrossRefGoogle ScholarPubMed
Baxby, D., Ashton, D. G., Jones, D. M., & Thomsett, L. R. (1982). An outbreak of cowpox in captive cheetahs: virological and epidemiological studies. Epidemiology and Infection 89, 365–372.Google ScholarPubMed
Baxby, D., Gaskell, R. M., Gaskell, C. J. & Bennett, M. (1986). Ecology of orthopoxviruses and use of recombinant vaccinia vaccines. Lancet ii, 850–851.CrossRefGoogle Scholar
Becker, T. M., Blount, J. H., Douglas, J. & Judson, F. N. (1986). Trends in molluscum contagiosum in the United States. Sexually Transmitted Diseases 13, 88–92.CrossRefGoogle ScholarPubMed
Bennett, M., Gaskell, C. J., Gaskell, R. M., Baxby, D. & Gruffyd-Jones, T. J. (1986). Poxvirus infection in the domestic cat: some clinical and epidemiological observations. Veterinary Record 118, 387–390.CrossRefGoogle ScholarPubMed
Black, D. N., Hammond, J. M., & Kitching, R. P. (1986). Genomic relationship between capripoxviruses. Virus Research 5, 277–292.CrossRefGoogle ScholarPubMed
Brown, F., Schild, G. C. & Ada, G. L. (1986). Recombinant vaccinia viruses as vaccines. Nature 119, 549–550.CrossRefGoogle Scholar
Brown, S. T., Nalley, J. F. & Kraus, S. J. (1981). Molluscum contagiosum. Sexually Transmitted Diseases 8, 227–234.CrossRefGoogle ScholarPubMed
Buller, R. M. L., Smith, G. L., Kremer, K., Notkins, A. L. & Moss, B. (1985). Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase negative phenotype. Nature 317, 813–815.CrossRefGoogle ScholarPubMed
Capps, L., Vermund, S. H. & Johnsen, C. (1986). Smallpox and biological warfare: the case for abandoning vaccination of military personnel. American Journal of Public Health 76. 1229–1231.CrossRefGoogle ScholarPubMed
Casemore, D. P., Emslie, E. S., Whyler, D. K., Baxby, D., Bennett, M. & Davies, A. B. (1987). Cowpox in a child, acquired from a cat. Clinical and Experimental Dermatology 12. 286–287.CrossRefGoogle Scholar
CDC (1985). Contact spread of vaccinia from a National Guard vaccinee–Wisconsin. Journal of the American Medical Association 253, 2348.CrossRefGoogle Scholar
Chakrabarti, S., Robert-Guroff, M., Wong-Staal, F., C.Gallo, R. Gallo, R. & Moss, B. (1986). Expression of HTLV-III envelope gene by recombinant vaccinia virus. Nature 320. 535–537.CrossRefGoogle ScholarPubMed
Christie, A. B. (1980). Infectious Diseases 3rd ed. p. 248, Edinburgh: Churchill-Livingstone.Google Scholar
Davies, F. G. & Mbugwa, G. (1985). The alterations in pathogenicity and immunogenicity of a Kenya sheep and goat pox virus on serial passage in bovine foetal muscle cell cultures. Journal of Comparative Pathology 95, 566–572.CrossRefGoogle ScholarPubMed
Davies, F. G., Mbugua, H., Atema, C. & Wilson, A. (1985). The prevalence of antibody to camelpox virus in six different herds in Kenya. Journal of Comparative Pathology 95, 633–655.CrossRefGoogle Scholar
Dougherty, W. G., Franke, C. A. & Hruby, D. E. (1986). Construction of a recombinant vaccinia virus which expresses immunoreactive plant virus proteins. Virology 149. 107–113.CrossRefGoogle ScholarPubMed
Dumbell, K. R. (1987). What should be done about smallpox virus? Lancet ii, 957–958.CrossRefGoogle Scholar
Dumbell, K. R. & Archard, L. C. (1980). Comparison of white pock (h) mutants of monkeypox virus with parental monkeypox virus and with variola-like viruses isolated from animals. Nature 286, 29–32.CrossRefGoogle Scholar
Dumbell, K. R. & Kapsenberg, H. G. (1982). Laboratory investigation of two ‘whitepox’ viruses and comparison with two variola strains from southern India. Bulletin of the World Health Organization 60, 381–387.Google ScholarPubMed
Esposito, J. J. & Knight, J. C. (1985). Orthopoxvirus DNA: a comparison of restriction profiles and maps. Virology 143, 230–251.CrossRefGoogle ScholarPubMed
Esposito, J. J., Nakano, J. H. & Obijeski, J. F. (1985). Can variola-like viruses be derived from monkeypox virus? An investigation based on DNA mapping. Bulltin of the World Health Organization 63, 695–703.Google ScholarPubMed
Fenner, F., Henderson, D. A., Arita, I., Jezek, Z. & Ladnyi, I. D. (1988). Smallpox and its Eradication. Geneva: World Health Organization.Google Scholar
Fornaciari, G. & Marchetti, A. (1986). Italian smallpox of the sixteenth century. Lancet ii, 1469–1470.CrossRefGoogle Scholar
Foster, S. O., Brink, E. W., Hutchins, D. L., Pifer, J. M., Lourie, B., Moser, C. R., Cummins, E. C., Kuteyi, O. E. K., Eke, R. E. A., Titus, J. B., Smith, E. A., Hicks, J. W. & Foege, W. H. (1972). Human monkeypox. Bulletin of the World Health Organization 46, 569–576.Google ScholarPubMed
Gaskell, R. M., Gaskell, C. J., Evans, R. J., Dennis, P. E., Bennett, A. M., Udall, N. D., Voyle, C. & Hill, T. J. (1983). Natural and experimental poxvirus infection in the domestic cat. Veterinary Record 112, 164–172.CrossRefGoogle ScholarPubMed
Gaskell, R. M., Baxby, D. & Bennett, M. (1988). Poxviruses. In Virus Infections of Carnivores (ed. Appel, M. J.), pp. 217–226. New York: Elsevier.Google Scholar
Gassman, U., Wyler, R. & Witter, R. (1985). Analysis of poxvirus genomes. Archives of Virology 83, 17–31.CrossRefGoogle Scholar
Gispen, R. & Brand-Saathof, B.‘White’ poxviruses from monkeys. Bulletin of the World Health Organization 46, 585–592.Google Scholar
Halsey, N. A. & Henderson, D. A. (1987). HIV infection and immunization against other agents. New England Journal of Medicine 316, 683–685.CrossRefGoogle ScholarPubMed
HMSO (1974). Report of the Committee of Inquiry into the Smallpox Outbreak in London in March and April 1973 London: HMSO.Google Scholar
HMSO (1980). Report of the Investigation into the Cause of the 1978 Birmingham Smallpox Occurrence London: HMSO.Google Scholar
Hruby, D. E. & Thomas, G. (1987). Use of vaccinia virus to express biopharmaceutical products. Pharmaceutical Research 4, 92–97.CrossRefGoogle ScholarPubMed
Hu, S.-K., Kosowski, S. G. & Dalrymple, J. M. (1986). Expression of AIDS virus envelope gene in recombinant vaccinia virus. Nature 320, 537–540.CrossRefGoogle Scholar
Hutchinson, H. D., Ziegler, D. W., Wells, D. E. & Nakano, J. H. (1977). Differentiation of variola, & monkeypox, and vaccinia antisera by radioimmunoassay. Bulletin of the World Health Organization 55, 613–623.Google ScholarPubMed
Jezek, Z., Arita, I., Szczeniowski, M., Paluku, K. M., Ruti, K. & Nakano, J. H. (1985). Human tanapox in Zaire: clinical and epidemiological observations on cases confirmed by laboratory studies. Bulletin of the World Health Organization 63, 1027–1035.Google ScholarPubMed
Jezek, Z., Arita, I., Mutombo, M., Dunn, C., Nakano, J. H. & Szczeniowski, M. (1986 a). Four generations of probable person-to-person transmission of human monkeypox. American Journal of Epidemiology 123, 1004–1012.CrossRefGoogle ScholarPubMed
Jezek, Z., Marennikova, S. S., Mutumbo, M., Nakano, J. H., Paluku, K. M. & Szczeniowski, M. (1986 b). Human monkeypox: a study of 2,510 contacts of 214 patients. Journal of Infectious Diseases 154, 551–555.CrossRefGoogle ScholarPubMed
Jezek, Z., Szczeniowski, M., Paluku, K. M. & Mutombo, M. (1987). Human monkeypox: clinical features of 282 patients. Journal of Infectious Diseases 156, 293–297.CrossRefGoogle ScholarPubMed
Kaplan, C., Healing, T. D., Evans, N., Healing, L. & Prior, A. (1980). Evidence of infection by viruses in small British field rodents. Epidemiology and Infection 84, 285–294.Google ScholarPubMed
Khodakevich, L., Jezek, Z. & Kinzanzka, K. (1986). Isolation of monkeypox virus from wild squirrel infected in nature. Lancet i, 98–99.CrossRefGoogle Scholar
Khodakevich, L., Szczeniowski, M., Manbu-Ma-Disu, , Jezek, Z., Marennikova, S., Nakano, J. & Messinoer, D. (1987). The role of squirrels in sustaining monkeypox virus transmission. Tropical and Geographical Medicine 39, 115–122.Google ScholarPubMed
Kitching, P. (1983). Progress towards sheep and goat pox vaccines. Vaccine 1, 4–9.CrossRefGoogle ScholarPubMed
Kitchino, R. P. & Taylor, W. P. (1985). Clinical and antigenic relationship between isolates of sheep and goat pox viruses. Tropical Animal Health Production 7, 64–74.CrossRefGoogle Scholar
Kitching, R. P., Hammond, J. M. & Taylor, W. P. (1987). A single vaccine for the control of capripoxvirus infection. Research in Veterinary Science 42, 53–60.CrossRefGoogle Scholar
Kriz, B. (1982). A study of camelpox in Somalia. Journal of Comparative Pathology 92, 1–8.CrossRefGoogle ScholarPubMed
Ladnyi, I. D., Ziegler, P. & Kima, E. (1972). A human infection caused by monkeypox virus in Basunku Territory, Democratic Republic of the Congo. Bulletin of the World Health Organization 46, 593–597.Google Scholar
Lancet, (1986). What's new pussycat? Cowpox. Lancet ii. 668.Google Scholar
Lancet, (1987). Monkeypox in Africa: future health hazard or public health nuisance? Lancet i, 369.Google Scholar
Lewin, P. K. (1985). Mummified frozen smallpox: is it a threat? Journal of the American Medical Association 253, 3095.CrossRefGoogle ScholarPubMed
Mackett, M., Smith, G. L. & Moss, B. (1982). Vaccinia virus: a selectable eukaryotic cloning and expression vector. Proceedings of the National Academy of Sciences, USA 79, 7415–7419.CrossRefGoogle ScholarPubMed
Mackett, M., Yilma, T., Rose, J. & Moss, B. (1985). Vaccinia virus recombinants: expression of VSV genes and protective immunization of mice and cattle. Science 227, 433–435.CrossRefGoogle ScholarPubMed
Marennikova, S. S., Shelukhina, E. M. & Shenkman, L. S. (1976). ‘White wild’ (variola-like) pox viruses in rodents of Equatorial Africa. Ada Virologica 20, 80–82.Google ScholarPubMed
Marennikova, S. S., Maltseva, N. N., Korneeva, V. I. & Garanina, N. M. (1977). Outbreak of pox disease among Carnivora (Felidae) and Edentata. Journal of Infectious Diseases 135, 358–366.CrossRefGoogle ScholarPubMed
Marennikova, S. S., Ladnyi, I. D., Ogorodnikova, Z. I., Shelukhina, E. M., Maltseva, N. N. (1978). Identification and study of a poxvirus isolated from wild rodents in Turkmenia. Archives of Virology 56, 7–14.CrossRefGoogle ScholarPubMed
Marennikova, S. S., Shelukhina, E. M., Maltseva, N. N. & Matsevich, G. R. (1979). Monkeypox virus as a source of whitepox viruses. Intervirology 11, 333–340.CrossRefGoogle ScholarPubMed
Martland, M. F., Poulton, G. J. & Done, R. A. (1985). Three cases of cowpox infection of domestic cats. Veterinary Record 117, 231–233.CrossRefGoogle ScholarPubMed
Mutombo, Mutombo Wa, Arita, I. & Jezek, Z. (1983). Human monkeypox transmitted by a chimpanzee in a tropical rain-forest area of Zaire. Lancet i, 735–737.CrossRefGoogle Scholar
New Item (1985). The virus in the crypt. New Scieyitist 107, (1465), 19.Google Scholar
News Item (1987 a). Smallpox vaccine ‘triggered AIDS virus’. Times (London) 05 11, pp. 1, 8.Google Scholar
News Item (1987 b). Scientists dismiss theory linking AIDS to smallpox. Independent (London) 05 12, p. 13.Google Scholar
Oriel, J. D. (1987). The increase in molluscum contagiosum. British Medical Journal 294, 74.CrossRefGoogle ScholarPubMed
Panicali, D. & Paoletti, E. (1982). Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. Porceedings of the National Academy of Sciences, USA 79, 4927–4931.CrossRefGoogle ScholarPubMed
Paoletti, E., Perkus, M., Piccini, A., Wos, S. M., Lipinskas, B. R. & Mercer, S. R. (1985). Gentically engineered poxviruses expressing multiple foreign genes. In Vaccines 85 (ed Lerner, R. A. and Chanock, R. M.). Cold Spring Harbor, New York.Google Scholar
Pether, J. V. S., Trevains, P. H., Harrison, S. R. B., Baxby, D., Bennett, M. & Gibb, A. P. R. (1986). Cowpox from cat to man. Lanceti, 38–39.CrossRefGoogle ScholarPubMed
Pilaski, J., Rosen, A. & Darai, G. (1986). Comparative analysis of the genomes of orthopoxviruses isolated from elephant, rhinoceros and okapi by restriction enzymes. Archives of Virology 88, 135–142.CrossRefGoogle ScholarPubMed
Porter, C. D., Muhlemann, M. F., Cream, J. J. & Archard, L. C. (1987). Molluscum contagiosum: characterization of viral DNA and clinical features. Epidemiology and Infection 99, 563–567.CrossRefGoogle ScholarPubMed
Quinnan, G. V. Jr, (ed.) (1985). Vaccinia viruses as vectors for vaccine antigens. New York: Elsevier.Google Scholar
Redfield, R. R., Wright, D. C., James, W. D., Jones, T. S., Brown, C. & Burke, D. S. (1987). Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease. New England Journal of Medicine 316, 673–676.CrossRefGoogle Scholar
Robinson, A. J. (1983). Prevalence of contagious pustular dermatitis (orf) in six million lambs at slaughter: a three year study. New Zealand Veterinary Journal 31, 161–3.CrossRefGoogle Scholar
Roslyakov, A. (1972). Comparison of ultrastructure of camelpox virus, the virus of a pox-like disease of camels and contagious ecthyma virus Voprosii Virusologii no. 17, 26–30.Google Scholar
Sidal, V. W. (1986). War or peace: smallpox and the use and abuse of public health. American Journal of Public Health 76, 1189–1190.CrossRefGoogle Scholar
Singh, I. P., Pandey, R. & Srivastava, R. N. (1979). Sheep pox; a review. Veterinary Bulletin 49, 145–154.Google Scholar
Smith, G. L., Mackett, M. & Moss, B. (1983). Infectious vaccinia virus recombinants that express Hepatitis B virus surface antigen. Nature 302, 490–495.CrossRefGoogle ScholarPubMed
Smith, G. L. & Moss, B. (1983). Infectious poxvirus vectors have capacity for at least 25,000 base pairs of foreign DNA. Gene 25, 21–28.CrossRefGoogle ScholarPubMed
Smith, G. L., Godson, G. N., Nussenzweig, V., Nussenzweig, R. S., Barnwell, J. & Moss, B. (1984). Plasmodium knowlesi sporozoite antigen: expression by infectious recombinant vaccinia virus. Science 224, 397–399.CrossRefGoogle ScholarPubMed
Symposium, (1977). Clinical and serologic study of four smallpox vaccines, comparing variation of dose and route of administration Journal of Infectious Diseases 135, 131–186.Google Scholar
Symposium, (1982). Report on the international conference on the eradication of infectious diseases. Can infectious diseases be eradicated? Review of Infectious Diseases 4, 912–984.Google Scholar
Thomsett, L. R., Baxby, D. & Denham, E. M. (1978). Cowpox in the domestic cat. Veterinary Record 108, 567.CrossRefGoogle Scholar
WHO (1980). Final Report of the Global Commission for the Certification of smallpox Eradication, Geneva: World Health Organization.Google Scholar
WHO (1986). Report of the Fourth Meeting of the Committee on Orthopoxvirus Infections, Geneva 24–26 March 1986. (WHO SE/86, 123), Geneva: World Health Organization.Google Scholar
Willemse, A. & Egberink, H. F. (1985). Transmission of cowpox virus infection from domestic cat to man. Lancet i, 1515.CrossRefGoogle Scholar
Zuckerman, A. J. (1984). Palaeontology of smallpox. Lancet ii, 1454.CrossRefGoogle Scholar