Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-23T22:20:10.429Z Has data issue: false hasContentIssue false
  • English
  • Français

Experimental infection of monkeys with Leptospira interrogans serovar hardjo

Published online by Cambridge University Press:  19 October 2009

M. F. Palmer ,
Sheena A. Waitkins ,
R. B. Fitzgeorge  and
A. Baskerville
M. F. Palmer
Affiliation:
Leptospira Reference Unit, County Hospital, Hereford, HR1 2ER, United Kingdom
Sheena A. Waitkins
Affiliation:
Leptospira Reference Unit, County Hospital, Hereford, HR1 2ER, United Kingdom
R. B. Fitzgeorge
Affiliation:
Experimental Pathology Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, United Kingdom
A. Baskerville
Affiliation:
Experimental Pathology Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, United Kingdom
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Grivet monkeys experimentally infected with two different strains of Leptospira interrogans serovar hardjo showed no signs of severe clinical disease. There were no significant macroscopic lesions in any of the tissues examined, but the organisms were demonstrated in various tissues by immunofluorescent technique and were isolated from the blood and urine of two monkeys and the kidney of one. Abraded skin was shown to be a viable route of infection in non-human primates.

Type
Research Article
Information
Epidemiology & Infection , Volume 98 , Issue 2 , April 1987 , pp. 191 - 197
Copyright
Copyright © Cambridge University Press 1987

References

REFERENCES

Anon. Editorial (1985). Veterinary Record 117, 331.Google Scholar
Ellinghausen, H. C. (1973). Growth temperatures, virulence survival and nutrition of leptospires. Journal of Medical Microbiology 6, 487–497.CrossRefGoogle ScholarPubMed
Ellis, W. A. (1980). The diagnosis of abortion due to leptospiral serovar hardjo. Proceedings 2nd International Symposium of Veterinary Laboratory Diagnosticians 1, 149–151.Google Scholar
Ellis, W. A. & Michna, S. Q. (1976). Bovine leptospirosis: Demonstration of leptospires of the Hebdomadis serogroup in aborted fetuses and a premature calf. Veterinary Record 99, 430–432.CrossRefGoogle Scholar
Ellis, W. A., O'Brien, J. J. & Cassells, J. (1981). Role of cattle in the maintenance of Leptospirosis interrogans serotype hardjo infection in Northern Ireland. Veterinary Record 108, 555–557.CrossRefGoogle ScholarPubMed
Ellis, W. A., O'Brien, J. J., Pearson, J. K. L. & Collins, D. S. (1976 a). Bovine leptospirosis: infection by the Hebdomadis serogroup and mastitis. Veterinary Record 99, 368–370.CrossRefGoogle ScholarPubMed
Ellis, W. A., O'Brien, J. J., Neill, S. D., Hanna, J. & Bryson, D. G. (1976 b). The isolation of leptospires from an aborted bovine foetus. Veterinary Record 99, 458–459.CrossRefGoogle Scholar
Ellis, W. A., O'Brien, J. J., Neill, S. S., Ferguson, H. W. & Hanna, J. (1982). Bovine leptospirosis: microbiological and serological findings in aborted foetuses. Veterinary Record 110, 147–150.CrossRefGoogle Scholar
Johnson, R. C. & Harris, V. G. (1967). Growth at low temperatures. Journal of Bacteriology 94, 27–31.CrossRefGoogle ScholarPubMed
Marshall, R. B., Baskerville, A., Hambleton, P. & Adams, G. D. J. (1980). Benign leptospirosis; the pathology of experimental and saprophytic leptospires 1; growth at low temperatures. Journal of Bacteriology 94, 27–31.Google Scholar
Marshall, R. B., Baskerville, A., Hambleton, P. & Adams, G. D. J. (1980). Benign leptospirosis; the pathology of experimental infection of monkeys with Leptospira interrogans serovars balcanica and tarassovi. British Journal of Experimental Pathology 61, 124–131.Google ScholarPubMed
Pritchard, D. G. (1986). The Present State of Leptospirosis Diagnosis and Control (ed. W. A.Ellis, and Little, T. W. A.), pp. 221–233. Netherlands: Martinus Nijehoff.Google Scholar
Smith, R. E., Reynolds, I. M. & Clark, G. W. (1967). Immunofluorescence in the diagnosis of bovine fetal leptospirosis. Cornell Veterinarian 57, 517–526.Google Scholar
Turner, L. (1968). Leptospirosis II. Transactions of the Royal Society of Tropical Medicine and Hygiene 62, 880–898.CrossRefGoogle ScholarPubMed
Waitkins, S. A. (1985). Update on Leptospirosis. British Medical Journal 290, 1502–1503.CrossRefGoogle ScholarPubMed
Woods, S. B., Maley, A. D., Frerichs, G. B. & Bailey, J. (1983). Isolation of a hamster lethal strain of Leptospira interrogans serotype hardjo. Veterinary Record 112, 437–438.CrossRefGoogle ScholarPubMed