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The Examination of Cotton, Coir and Esparto-Grass Dust for Histamine

Published online by Cambridge University Press:  15 May 2009

A. D. Macdonald  and
H. B. Maitland
A. D. Macdonald
Affiliation:
From the Department of Pharmacology and the Department of Bacteriology and Preventive Medicine in the University of Manchester
H. B. Maitland
Affiliation:
From the Department of Pharmacology and the Department of Bacteriology and Preventive Medicine in the University of Manchester
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As a result of some preliminary investigations upon the aetiology of an asthmatic type of disability among workers in carding-rooms of cotton mills, Maitland, Heap and Macdonald (1932) showed that it was possible to extract from some samples of cotton dust a substance which gave the biological reactions of histamine. The dust was that to which affected workers would be exposed. The amount of histamine recovered varied from 0·02 mg. to less than 0·004 mg. per g. of dust. Different bulk samples of dust contained unequal amounts, and the amount also varied in different fractions of one sample graded according to the size of dust particles. It was thought that the finer fractions contained the larger amounts of histamine and that some bulk samples were, relatively at any rate, histamine free.

Type
Research Article
Information
Journal of Hygiene , Volume 34 , Issue 3 , October 1934 , pp. 317 - 321
Copyright
Copyright © Cambridge University Press 1934

References

REFERENCES

Maitland, H. B., Heap, H. and MacDonald, A. D. (1932). Report of the Departmental Committee on Dust in Card Rooms in the Cotton Industry, Appendix vi. London: H.M. Stationery Office.Google Scholar