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Effect of stay in hospital and oral chemotherapy on the antibiotic sensitivity of bowel coliforms

Published online by Cambridge University Press:  15 May 2009

Elizabeth J. Shaw ,
Naomi Datta ,
Glynne Jones ,
Frances M. Marr  and
Wendy J. B. Froud
Elizabeth J. Shaw
Affiliation:
Bacteriology Department, Royal Postgraduate Medical School, LondonW12 0HS
Naomi Datta
Affiliation:
Bacteriology Department, Royal Postgraduate Medical School, LondonW12 0HS
Glynne Jones
Affiliation:
Department of Respiratory Diseases, City Hospital, Edinburgh
Frances M. Marr
Affiliation:
Department of Respiratory Diseases, City Hospital, Edinburgh
Wendy J. B. Froud
Affiliation:
Department of Respiratory Diseases, City Hospital, Edinburgh
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Summary

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The effects of oral chemotherapy and stay in hospital on the antibiotic resistance patterns of faecal coliform flora were studied. The coliform flora of 64% of 25 patients who were not receiving antibiotics was sensitive to all drugs tested. Hospitalization alone did not affect this proportion. The administration of tetra-cycline or ampicillin to patients, whether at home or in hospital, significantly increased the percentage of resistant bowel coliforms. Tetracycline showed a significantly greater effect than ampicillin. There was no significant increase in the percentage of patients with resistant flora after treatment with amoxycillin.

Type
Research Article
Information
Journal of Hygiene , Volume 71 , Issue 3 , September 1973 , pp. 529 - 534
Copyright
Copyright © Cambridge University Press 1973

References

REFERENCES

Datta, N. (1969). Drug resistance and R factors in the bowel bacteria of London patients before and after admission to hospital. British Medical Journal ii, 407–11.CrossRefGoogle Scholar
Datta, N., Faiers, M., Reeves, D. S., Brumfitt, W., Orskov, F. & Orskov, I. (1971). R factors in Escherichia coli in faeces after oral chemotherapy in medical practice. Lancet i, 312–15.CrossRefGoogle Scholar
Jones, G. R., Calder, M. A., Froud, W. J. B., Inglis, J. M., Marr, F. M. & Stewart, S. M. (1973). Amoxycillin – pilot study of its use in pneumonia and chronic bronchitis. British Journal of Clinical Practice (in the Press).Google ScholarPubMed
Moorhouse, E. C. (1969). Transferable drug resistance in Enterobacteria isolated from urban infants. British Medical Journal ii, 405–7.CrossRefGoogle Scholar
Sutherland, R., Croydon, E. A. P. & Rolinson, G. N. (1972). Amoxycillin: a new semisynthetic penicillin. British Medical Journal iii, 13–16.CrossRefGoogle Scholar