Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-07T06:13:08.677Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of maternally derived antibodies on the response of calves to vaccination against foot and mouth disease

Published online by Cambridge University Press:  19 October 2009

M. J. Nicholls ,
L. Black ,
M. M. Rweyemamu ,
J. Genovese ,
R. Ferrari ,
C. A. Hammant ,
E. de Silva  and
O. Umehara
M. J. Nicholls
Affiliation:
Wellcome Biotechnology Limited, Wellcome FMD Vaccine Laboratory, Pirbright, Surrey, U.K.
L. Black
Affiliation:
Wellcome Biotechnology Limited, Wellcome FMD Vaccine Laboratory, Pirbright, Surrey, U.K.
M. M. Rweyemamu
Affiliation:
Wellcome Biotechnology Limited, Wellcome FMD Vaccine Laboratory, Pirbright, Surrey, U.K.
J. Genovese
Affiliation:
Cooper-Uruguay Laboratories, Montevideo, Uruguay
R. Ferrari
Affiliation:
Cooper-Uruguay Laboratories, Montevideo, Uruguay
C. A. Hammant
Affiliation:
Laboratorios Wellcome, Cotia, Sãao Paulo, Brazil
E. de Silva
Affiliation:
Laboratorios Wellcome, Cotia, Sãao Paulo, Brazil
O. Umehara
Affiliation:
Laboratorios Wellcome, Cotia, Sãao Paulo, Brazil
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Studies were carried out in South America to assess the effect of maternally derived antibody (MDA) on the responsiveness of calves to FMD vaccination. It was found that calves with MDA did not merely fail to respond to vaccination, but that their serum titres were depressed. This depression was proportional to the level of pre-existing MDA at the time of vaccination and following primary vaccination it persisted for a least 60 days. High MDA titres interfered with both primary and secondary responses. Animals with relatively low MDA titres were able to respond to vaccination, or at least to be sensitized so that on revaccination they showed a satisfactory response. The half-life of MDA was shown to be approximately 22 days, suggesting that under field conditions significant MDA titres are likely to persist for 4–5 months. A trial carried out in Brazil in which the primary course of two inoculations, 4 weeks apart, was initiated when the calves were 5–6 months of age, resulted in the reduction of FMD in the calf population from 11% to 0·9% over a 12-month period. The use of vaccination programmes of this type to lessen the incidence of FMD in young bovines is discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 92 , Issue 1 , February 1984 , pp. 105 - 116
Copyright
Copyright © Cambridge University Press 1984

References

REFERENCES

Adler, E., Murillo, P. A. & Rivenson, S. (1966). Vacunas oleosas. Preparation de una emulsion estable tipo ‘agua en aceite’. Revista de Investigations Agricolas, Buenos Aires 3, 1–14.Google Scholar
Auge de Mello, P. & Gomes, I. (1977). Anamnestic response in cattle after revaccination with oil adjuvanted foot and mouth disease vaccines. Boletin del Centro Panamericano de Fiebre Aftosa 26, 27–29.Google Scholar
Brar, J. S., Johnson, D. W., Muscoplat, C. C., Shope, R. E. Jr & Meiske, J. C. (1978). Maternal immunity to infectious bovine rhinotracheitis virus and bovine viral diarrhoea virus, duration and effect on vaccination in young calves. American Journal of Veterinary Research 39, 241–244.Google ScholarPubMed
Brun, A., Chappuis, G., Favre, H., Roulet, C. & Terre, J. (1977). Utilisation chez les jeunes bovins du vaccin antiaphteux en adjuvant huileux. Developments in Biological Standardisation 35, 117–122.Google Scholar
Casas, Olascoaga R. (1978). Situation of the foot and mouth disease control programmes in South America. British Veterinary Journal 134, 16–22.CrossRefGoogle Scholar
Cunliffe, H. R. & Graves, J. H. (1963). Formalin-treated FMD virus: Comparison of two adjuvants in cattle. Canadian Journal of Comparative Medicine 27, 193–197.Google Scholar
Eissner, G., Uhlmann, W. & Lorenz, R. J. (1972). Recherches sur le taux d'anticorps chez de jeunes bovins de différentes races après une premiere vaccination anti-aphteuse avec des vaccins obtenus pur differentes modes de production. Bulletin de l'Office International des Epizootics 77, 995–1003.Google Scholar
Eskildsen, M. K. (1969). Experimental pulmonary infection of cattle with foot and mouth disease virus. Nordiska Veterinaermedicin 21, 86–91.Google Scholar
Francis, M. J., Ouldridoe, E. J. & Black, L. (1983). Antibody response in bovine pharyngeal fluid following foot and mouth disease vaccination and/or exposure to live virus. Research in Veterinary Science 35, 206–210.CrossRefGoogle ScholarPubMed
Glushko, B. A. (1964). The dynamics of antibody titres against FMD in newborn calves. Veterinariya (Moscow) 41, 20–21.Google Scholar
Graves, J. H. (1963). Transfer of neutralising antibody by colostrum to calves born of FMD vaccinated dams. Journal of Immunology 91, 251–256.CrossRefGoogle Scholar
Henderson, W. M. (1978). A historical review of the control of foot and mouth disease. British Veterinary Journal 134, 3–9.CrossRefGoogle Scholar
Hyslop, N. St. G. (1965). Airborne infection with the virus of foot and mouth disease. Journal of Comparative Pathology 75, 119–126.CrossRefGoogle ScholarPubMed
Ishikawa, H. & Konishi, T. (1982). Changes in serum immunoglobulin concentrations of young calves. Japanese Journal of Veterinary Science 44, 555–563.Google ScholarPubMed
Kruglikov, B. A., Antonyuk, V. P., Barbashov, V. P., Cherynsheva, G. T., Petrova, L. K., Yurchenko, A. N., Ervandryan, G. B., Karpunin, N. D., Avaliani, R. I. & Guliev, M. A. (1974). Results of simultaneous administration of monovalent, formalininactivated, gel adsorbed FMD vaccine prepared from Lapinised A22 and O1 virus strains from the Georgian SSR. Trudy-Gosudarstvennogo Nauchno Issledovatelskogo Instituta 20, 84–87.Google Scholar
LaMotte, G. B. (1977). Total serum protein, serum protein fractions and serum immunoglobulins in colostrum-fed and colostrum-deprived calves. American Journal of Veterinary Research 38, 263–268.Google ScholarPubMed
Martin, W. B. & Chapman, W. G. (1961). The tissue culture colour test for assaying the virus and neutralising antibody of foot and mouth disease and its application to the measurement of immunity in cattle. Research in Veterinary Science 2, 53–61.CrossRefGoogle Scholar
Mowat, G. N., Garland, A. J. & Spier, R. E. (1978). The development of foot and mouth disease vaccines. Veterinary Record 102, 190–193.Google Scholar
Muntiu, N., Dohotaru, V., Bercan, A., Mircescu, G., Tomescu, A., & Stirbu, C. (1969). Effect of age of cattle on the post-vaccinal foot and mouth disease immunity. Archiva Velerinaria 6, 3–13.Google Scholar
Nicholls, M. J. (1983). Factors affecting the response of young bovines to vaccination against FMD. Thesis, Liverpool University.Google Scholar
Nicholls, M. J., Black, L., Rweyemamu, M. M. & Gradwell, D. V. (1984). The effect of age on response of cattle to vaccination against FMD. British Veterinary Journal (in the Press).Google Scholar
Prudovsky, S. (1973). Some aspects of the immune response of cattle to FMD vaccines. Refuah Veterinarith 30, 77–84.Google Scholar
Rivenson, S. (1972). Estudio comparativo con un neuvo tipo de vacuna antiaftosa oleosa en bovinos. Revista de Investigaciones Agricolas, Buenos Aires 9, 53–80.Google Scholar
Rweyemamu, M. M., Pay, T. W. F., Simms, M. J. (1982). The control of foot and mouth disease by vaccination. The Veterinary Annual, 22nd ed. (ed. Grunsell, C. S. G. and Hill, F. W. G.). Bristol: Publ. Scientechnica.Google Scholar
Sasaki, M., Davis, C. L. & Larson, B. L. (1977). Immunoglobulin IgG, metabolism in newborn calves. Journal of Dairy Science 60, 623–626.CrossRefGoogle Scholar
Scott, J. M., Pegram, R. G., Holmes, H. H., Pay, T. W. F., Knoght, P. A., Jennings, F. W. & Urquhart, G. M. (1977). Immunosuppression in bovine trypanosomiasis. Tropical Animal Health and Production 9, 159–165.CrossRefGoogle ScholarPubMed
Sellers, R. F. (1971). Quantitative aspects of the spread of foot and mouth disease. Veterinary Bulletin 41, 431–439.Google Scholar
Shankar, H. & Uppal, P. K. (1981). Transfer of antibodies through colostrum in calves born to FMD vaccinated cows. Indian Journal of Animal Science 51, 622–626.Google Scholar
Shankar, H. & Uppal, P. K. (1982). Immune response of newborn calves to vaccination with foot and mouth disease vaccine. Revue Scienlifique et Technique de l'Office International des Epizooties 1, 403–414.CrossRefGoogle Scholar
Srubar, B. (1966). Studies on specific colostral immunity in the calves of cows vaccinated against FMD. Veterinary Medicine (Prague) 11, 511–588.Google Scholar
Sutmoller, P. & Vieira, A. (1980). The relationship of neutralising antibody titres for foot and mouth disease virus and the protection of cattle. Boletin del Centro Panamericano de Feibre Aftosa 39–40, 57–62.Google Scholar
Tekerlekov, P., Urchev, K., Nikolova, E., Genov, I., Tsutsumanski, V., Kirilov, N. & Genchev, G. A. (1980). Investigations on the specific immunoprophylaxis of calves against foot and mouth disease. Veterinarno-Meditsinki Nauki (Sofia) 17, 28–34.Google Scholar
Telling, R. C., Capstick, P. B., Pay, T. W. F. & Menard, F. J. R. R. (1972). The large scale manufacture of foot and mouth disease vaccines by the BHK deep suspension culture method. Proceedings of the 2nd International Congress of Virology, Budapest, 1971.Google Scholar
Todd, J. D. (1973). Immune response to parental and intranasal vaccinations. Journal of the American Veterinary Medical Association 163, 807–809.Google Scholar
Uppal, P. K., Kumar, S., Das, S. K.&Bhatt, P. N. (1975). Foot and mouth disease vaccination in newly born calves. Indian Veterinary Journal 52, 282–288.Google Scholar
Van Bekkum, J. G. (1966). The influence of FMD vaccination of the mother on the level of neutralising antibody in her young. Bulletin de l'Office International des Epizooties 65, 439–442.Google Scholar
Wisniewsky, J. & Jankowska, J. (1972). Effect of passive immunity of calves acquired by colostrum on the results of vaccination against FMD. Bulletin-Veterinary Institute in Pulawy 16, 46–51.Google Scholar