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Contamination of Apparatus During Freeze-Drying

Published online by Cambridge University Press:  15 May 2009

D. Busby
Affiliation:
National Institute for Medical Research, Mill Hill, London, N.W. 7
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When the manifold system of freeze-drying is used the practice of plugging the tubes containing the product to be dried would seem to be necessary. It should be emphasized that a loose plug implies teased out cotton-wool and not just a loosely fitting one. Virus was recovered from the drying apparatus under various conditions when unplugged tubes were used. No virus contamination could be demonstrated when the tubes were plugged.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1959

References

REFERENCES

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