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Comparative trial of three heterologous anti-tetanus sera

Published online by Cambridge University Press:  15 May 2009

I. S. R. Sinclair ,
J. St G. McCormick  and
J. G. Clark
I. S. R. Sinclair
Affiliation:
The Royal Infirmary, Edinburgh
J. St G. McCormick
Affiliation:
The Royal Infirmary, Edinburgh
J. G. Clark
Affiliation:
The Royal Infirmary, Edinburgh
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Summary

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The three heterologous anti-sera currently provided for tetanus prophylaxis have been compared with reference to the production of untoward reactions in 498 patients, and to the blood antitoxin concentrations produced in 76 patients. Equine serum, although giving rise to more reactions, was the only effective agent in terms of the levels and duration of serum antitoxin concentration produced. The local response to a test dose of any of the three sera is not a reliable guide to immediate or late general reactions.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 2 , June 1971 , pp. 201 - 207
Copyright
Copyright © Cambridge University Press 1971

References

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