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A comparative study of two live measles vaccines in Iran

Published online by Cambridge University Press:  15 May 2009

H. Mirchamsy ,
A. Shafyi ,
Y. Bassali ,
S. Bahrami  and
F. Nazari
H. Mirchamsy
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
A. Shafyi
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
Y. Bassali
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
S. Bahrami
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
F. Nazari
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
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Summary

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The results of immunization of 523 children from 9 months to over 5 years of age with two attenuated measles vaccines, ‘Denken’ and ‘Biken’, are described. The clinical reactions following vaccination with both vaccines were mild, but Denken vaccine produced more rashes than the Biken vaccine. The serological conversion was satisfactory for both vaccines but a higher titre of neutralizing and haemagglutination-inhibiting antibodies was found in children immunized with Denken vaccine. The incidence of severe reactions or complications was negligible in this trial. The immunity to diphtheria or tetanus was not altered by vaccination with live measles vaccine.

Type
Research Article
Information
Journal of Hygiene , Volume 68 , Issue 1 , March 1970 , pp. 101 - 110
Copyright
Copyright © Cambridge University Press 1970

References

Enders, J. F., Katz, S. L., Milovanovic, M. V. & Holloway, A. (1960). A study on an attenuated measles vaccine. I. Development and preparation of the vaccine; technics for assay of effects of vaccination. New England Journal of Medicine 263, 153.CrossRefGoogle Scholar
Fadeeva, L. L., Dadashyan, M. A., Lebedev, D. D. & Zhdanov, V. M. (1960). Attenuated measles virus strain in the U.S.S.R. American Journal of Diseases of Children 103, 379.Google Scholar
Kunita, N., Kitavaki, T., Funahashi, S. & Toyoshima, K. (1963). Comparison of the haemagglutination inhibition test for measles with serological tests and its application to a field trial. Biken Journal 6, 45.Google ScholarPubMed
Matumoto, M., Mutai, M., Ogiwara, H. & Nakamura, M. (1961). Prolifération du virus rougeoleux en culture de cellules rénales bovines. Comptes Rendus des Scéances de la Société de Biologie 155, 1192.Google Scholar
Matumoto, M., Mutai, M., Saburi, Y., Fuji, R., Minamitani, M. & Nakamura, K. (1962). Live measles-virus vaccine: clinical trial of vaccine prepared from a variant of the Sugyama strain adapted to bovine kidney cells. Japanese Journal of Experimental Medicine 32, 433.Google Scholar
Mirchamsy, H., Nazari, F., Stellman, C. & Esterabady, H. (1968). The use of dried whole blood absorbed on filter-paper for the evaluation of diphtheria and tetanus antitoxins in mass surveys. Bulletin of the World Health Organization 38, 665.Google ScholarPubMed
Mirchamsy, H. & Rapp, F. (1969). Role of interferon in replication of virulent and attenuated strains of measles virus. Journal of General Virology 4, 513.CrossRefGoogle ScholarPubMed
Nafyci, K., Saidi, S., Nategh, R., Mostatab, A. & Akbarshahy, R. (1967). Comparative study of live attenuated and further attenuated measles vaccines in rural areas of Iran. Archiv für die gesamte Virusforschung 22, 11.CrossRefGoogle Scholar
Norrby, E. (1964). A sensitive measles HAI test. Proceedings of the International Symposium of Measles Vaccine Standardization. Measles and Rubella Serology, Lyon, France, page 186.Google Scholar
Okuno, Y., Sugai, T., Toyoshima, K., Takahashi, M., Yamamura, T., Hata, S., Niki, T., Nakamura, K., Ueda, S. & Kunita, N. (1960). Studies on the prophylaxis of measles with attenuated living virus. IV. Inoculation tests in children with chick embryo passage measles virus in 1960. Biken Journal 3, 293.Google Scholar
Parisius, W. & Macmorine, H. G. (1969). Effects of tween 80 and Freon 113 on measles virus. Applied Microbiology 17, 379.CrossRefGoogle ScholarPubMed
Rosen, L. (1961). Haemagglutination and haemagglutination-inhibition with measles virus. Virology 13, 139.CrossRefGoogle ScholarPubMed
Smorodintsev, A. A., Baichuk, L. M., Shikina, E. S., Batanova, T. B., Bystryakova, L. V. & Peradze, T. V. (1960). Clinical and immunological response to live tissue culture vaccine against measles. Acta Virologica (English edition), 4, 201.Google ScholarPubMed
Ueda, S., Hosai, H., Minekawa, Y. & Okuno, Y. (1966). Studies on the combined use of killed and live measles vaccine. III. Conditions for the ‘take’ of live vaccine. Biken Journal 9. 97.Google Scholar