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Clinical and subclinical variola minor in a ward outbreak

Published online by Cambridge University Press:  15 May 2009

Luis F. de Salles-Gomes ,
Juan J. Angulo ,
Ernaldo Menezes  and
Vinicio A. Zamith
Luis F. de Salles-Gomes
Affiliation:
Instituto Adolfo Lutz and Santa Casa de Misericórdia, São Paulo, Brazil
Juan J. Angulo
Affiliation:
Instituto Adolfo Lutz and Santa Casa de Misericórdia, São Paulo, Brazil
Ernaldo Menezes
Affiliation:
Instituto Adolfo Lutz and Santa Casa de Misericórdia, São Paulo, Brazil
Vinicio A. Zamith
Affiliation:
Instituto Adolfo Lutz and Santa Casa de Misericórdia, São Paulo, Brazil
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A variola minor outbreak in a 36-bed hospital-ward comprised seven cases of overt variola after the first case. Clinical and epidemiological findings were typical, seven of the eight cases of overt variola being confirmed by virus isolation or antibody titrations. In addition, thirteen definite and seven possible instances of subclinical variola were deduced from complement-fixation or haemagglutination-inhibition tests. A discussion is made of the validity of serological criteria of variolous and vaccinial infections.

Type
Research Article
Information
Journal of Hygiene , Volume 63 , Issue 1 , March 1965 , pp. 49 - 58
Copyright
Copyright © Cambridge University Press 1965

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