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Chronic atrophic oral candidiasis among patients with diabetes mellitus – role of secretor status

Published online by Cambridge University Press:  15 May 2009

F. Z. Aly ,
C. C. Blackwell ,
D. A. C. MacKenzie ,
D. M. Weir ,
R. A. Elton ,
C. G. Cumming ,
J. A. Sofaer  and
B. F. Clarke
F. Z. Aly
Affiliation:
Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh EH8 9AG
C. C. Blackwell
Affiliation:
Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh EH8 9AG
D. A. C. MacKenzie
Affiliation:
Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh EH8 9AG
D. M. Weir
Affiliation:
Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh EH8 9AG
R. A. Elton
Affiliation:
Medical Statistics Unit, University of Edinburgh
C. G. Cumming
Affiliation:
Department of Oral Medicine and Oral Pathology, University of Edinburgh
J. A. Sofaer
Affiliation:
Department of Oral Medicine and Oral Pathology, University of Edinburgh
B. F. Clarke
Affiliation:
Department of Diabetes, Royal Infirmary, Edinburgh
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Summary

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Non-diabetic individuals who are non-secretors of blood group antigens are prone to superficial infections by Candida albicans. In this study, 216 patients with diabetes mellitus who were denture wearers were examined for the presence or absence of denture stomatitis. There was an overall trend for non-secretors to be prone to denture stomatitis compared with secretors. Stepwise linear discriminant analysis was used to dissect the contribution of secretor status and other variables to the development of the disease. Secretor status was found to be a contributory factor among patients with non-insulin dependent diabetes but not among those with insulin-dependent diabetes. The possible reasons for this are discussed.

Type
Special Article
Information
Epidemiology & Infection , Volume 106 , Issue 2 , April 1991 , pp. 355 - 363
Copyright
Copyright © Cambridge University Press 1991

References

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