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Antenatal survey for the seroprevalence of HTLV-1 infections in the West Midlands, England

Published online by Cambridge University Press:  19 October 2009

S. Nightingale ,
D. Orton ,
D. Ratcliffe ,
S. Skidmore ,
J. Tosswill  and
U. Desselberger
S. Nightingale
Affiliation:
Midland Centre for Neurosurgery and Neurology, Smethwick, West Midlands, B67 77X
D. Orton
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham B9 5ST
D. Ratcliffe
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham B9 5ST
S. Skidmore
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham B9 5ST
J. Tosswill
Affiliation:
Virus Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
U. Desselberger
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham B9 5ST
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The sera of 3522 women who attended an antenatal clinic in Birmingham. England were tested anonymously for antibodies against HTLV-1. Samples from 5 women (0·14%) were positive, one serum showed indeterminate reactivity. Two of the women (0·06%) were born in the West Indies (of Afro-Caribbean ethnic origin), one (0·03%) in Africa (of African ethnic origin), and three (0·09%) were white Caucasian women born in the UK. Thus, HTLV-1 infection in pregnant women in the UK, though comparatively rare, is not negligible. As transmission of HTLV-1 to the newborn via breast milk has been observed and as seropositive mothers can be advised to refrain from breastfeeding or to treat their milk, the question of routine screening for HTLV-1 infection during antenatal care is discussed.

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 2 , April 1993 , pp. 379 - 387
Copyright
Copyright © Cambridge University Press 1993

References

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