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An outbreak of Pseudomonas aeruginosa (pyocyanea) infection in a Premature Baby Unit, with observations on the intestinal carriage of Pseudomonas aeruginosa in the newborn

Published online by Cambridge University Press:  15 May 2009

C. H. Jellard  and
Gillian M. Churcher
C. H. Jellard
Affiliation:
Public Health Laboratory Service and Department of Pathology, Plymouth General Hospital, Greenbank Road, Plymouth
Gillian M. Churcher
Affiliation:
Public Health Laboratory Service and Department of Pathology, Plymouth General Hospital, Greenbank Road, Plymouth
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An outbreak of infection in a Premature Baby Unit due to a single strain of Pseudomonas aeruginosa is described. The outbreak lasted for 16 months, during which this organism was isolated from the faeces of 99/418 premature babies, many of them being symptomless carriers. There were seven deaths due to the infection. The source of the epidemic was not found. The main reservoir of infection was the babies' faeces. Though many full-term babies were symptomless carriers of the epidemic strain of Ps. aeruginosa, they were not ill.

Measures for control of the outbreak, and the aetiology of neonatal intestinal infection with Ps. aeruginosa are discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 65 , Issue 2 , June 1967 , pp. 219 - 228
Copyright
Copyright © Cambridge University Press 1967

References

Alison, F. (1961). Infections à Pseudomonas aeruginosa chêz le nouveau-né et le nourrisson. Actual. pédiat. 3rd ser. p. 321.Google Scholar
Asay, L. D. & Koch, R. (1960). Pseudomonas infections in infants and children. New Engl. J. Med. 262, 1062.CrossRefGoogle ScholarPubMed
Barrie, D. (1965). Incubator-borne Pseudomonas pyocyanea infection in a newborn nursery. Archs. Dis. Childh. 40, 555.CrossRefGoogle Scholar
Bassett, D. C. J., Thompson, S. A. S. & Page, B. (1965). Neonatal infections with Pseudomonas aeruginosa associated with contaminated resuscitation equipment. Lancet i, 781.CrossRefGoogle Scholar
Bielicka, I. & Dzieniszewska, L. (1953). Zakazenie paleczka ropy blekitnej u weześniaków. Polski Tygod. lek. 8, 1413.Google Scholar
Brádaĉ, O., Procnázková, R. & Sedlák, J. (1954). Epidemie smrtelných prujmu novorozencú s nálezem Pseudomonas aeruginosa (B. pyocyaneus). Pediat. Listy 9, 229.Google Scholar
Eggers, H. & Wöckel, W. (1958). The clinical picture and pathology of pyocyaneus infection in premature and full term neonates. Germ. med. Mon. 3, 45.Google Scholar
Florman, A. L. & Schifrin, N. (1950). Observations on a small outbreak of infantile diarrhoea associated with Pseudomonas aeruginosa. J. Pediat. 36, 758.CrossRefGoogle ScholarPubMed
Gavallér, B. v. (1958). Veränderungen durch Pyocyaneus bei Neugeborenen. Verh. dt. Ges. Path. 41, 213.Google Scholar
Gitlin, D., Rosen, F. S. & Michael, J. G. (1963). Transient 19S gamma-globulin deficiency in the newborn infant and its significance. Pediatrics, Springfield 31, 197.CrossRefGoogle ScholarPubMed
Hoffman, M. A. & Finberg, L. (1955). Pseudomonas infections in infants associated with high humidity environments. J. Pediat. 46, 626.CrossRefGoogle ScholarPubMed
Hunter, C. A. & Ensign, P. R. (1947). An epidemic of diarrhoea in a newborn nursery caused by Pseudomonas aeruginosa. Am. J. publ. Hlth. 37, 1166.CrossRefGoogle Scholar
Jacobs, J. (1964). The investigation of an outbreak of Pseudomonas pyocyanea infection in a pediatric unit. Post-grad. med. J. 40, 590.CrossRefGoogle Scholar
Jones, R. I. & Lowbury, E. J. L. (1965). Susceptibility of man to Pseudomonas aeruginosa. Lancet ii, 623.CrossRefGoogle Scholar
Kelsey, J. C. & Mauber, I. M. (1966). An in-use test for hospital disinfectants. Mon. Bull. Minist. Hlth 25, 180.Google Scholar
Kovacs, N. (1956). Identification of Pseudomonas pyocyanea by the oxidase reaction. Nature, Lond. 178, 703.CrossRefGoogle ScholarPubMed
Kwantes, W. (1960). An outbreak of acute otitis media in a maternity hospital due to Pseudomonas aeruginosa. Mon. Bull. Minist. Hlth 19, 169.Google Scholar
Linde, K., Koditz, H. & Kittlick, M. (1962). Untersuchungen zur Frage der Säuglings-enteritis durch Pseudomonas aeruginosa. Mschr. Kinderheilk. 110, 62.Google Scholar
Lowbury, E. J. L. & Collins, A. G. (1955). The use of a new Cetrimide product in a selective medium for Pseudomonas pyocyanea. J. clin. Path. 8, 47.CrossRefGoogle Scholar
McFarlan, A. M., Crone, P. B. & Tee, G. H. (1949). Variations in bacteriology of throat and rectum of infants in two maternity units. Br. med. J. ii, 1140.CrossRefGoogle Scholar
McLeod, J. W. (1958). The hospital urine bottle and bedpan as reservoirs of infection by Pseudomonas. Lancet i, 394.CrossRefGoogle Scholar
Neter, E. & Weintraub, D. H. (1955). An epidemiological study on Pseudomonas aeruginosa (Bacillus pyocyaneus) in premature infants in the presence and absence of infection. J. Pediat. 46, 280.CrossRefGoogle ScholarPubMed
Paul, R. & Marget, W. (1964). Pseudomonas aeruginosa infections (pyocyaneus sepsis) in infancy. Germ. med. Mon. 9, 119.Google Scholar
Primavesi, C. A. (1964). Pyocyaneus-Hospitalismus auf einer Neugeborenenstation. Dt. med. Wschr. 27, 1303.CrossRefGoogle Scholar
Public Health Laboratory Service Committee on Testing and Evaluation of Disinfectants (1965). Use of disinfectants in hospitals. Br. med. J. i, 408.Google Scholar
Rubbo, S. D., Gardner, J. F. & Franklin, J. C. (1966). Source of Pseudomonas aeruginosa infection in premature infants. J. Hyg., Camb. 64, 121.CrossRefGoogle ScholarPubMed
Schaffer, A. J. & Oppenheimer, E. H. (1948). Pseudomonas (Pyocyaneus) infection of the gastro-intestinal tract in infants and children. Sth. med. J., Nashville 41, 460.CrossRefGoogle ScholarPubMed
Sierra, G. (1957). A simple method for the detection of lipolytic activity of micro-organisms and some observations on the influence of contact between cells and fatty substrates. Antonie van Leeuwenhoek 23, 15.CrossRefGoogle ScholarPubMed
Verger, P. & Bentégeat, J. (1955). Une épidémic d'entérite à bacille pyocyanique (Pseudomonas aeruginosa) observeé dans un centre de prématurés. Nourrisson 43, 141.Google Scholar
Wahba, A. H. & Darrell, J. H. (1965). The identification of atypical strains of Pseudomonas aeruginosa. J. gen. Microbiol. 38, 329.CrossRefGoogle ScholarPubMed
Wensinck, F., Van Bekkum, D. W. & Renaud, H. (1957). The prevention of Pseudomonas aeruginosa infections in irradiated mice and rats. Radiat. Res. 7, 491.CrossRefGoogle ScholarPubMed
Wilson, M. G., Nelson, R. C., Phillips, L. H. & Boak, R. A. (1961). New source of Pseudomonas aeruginosa in a nursery. J. Am. med. Ass. 175, 1146.CrossRefGoogle Scholar