Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-03T01:30:40.988Z Has data issue: false hasContentIssue false
  • English
  • Français

Aerosol exposure of cattle to foot-and-mouth disease virus

Published online by Cambridge University Press:  19 October 2009

John W. McVicar  and
Robert J. Eisner
John W. McVicar
Affiliation:
Plum Island Animal Disease Center, USDA, ARS, S&E, P.O. Box 848, Greenport, New York 11944
Robert J. Eisner
Affiliation:
Plum Island Animal Disease Center, USDA, ARS, S&E, P.O. Box 848, Greenport, New York 11944
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Slight modifications of a small, plastic covered greenhouse provided a chamber for the exposure of cattle of all ages to aerosols of foot-and-mouth disease virus. Particle size distributions of aerosols were 76% < 3 μm, 17% 3–6 μm, and 7% > 6 μm immediately after the deVilbis no. 40 nebulizer used was turned off and 90% < 3 μm, 8% 3–6 μm, and 2% > 6 μm 20–30 min later. Pharyngeal virus growth curves and viremia patterns correlated well with the dose of virus to which test cattle were exposed and were similar to those of cattle inoculated intranasally.

Type
Research Article
Information
Journal of Hygiene , Volume 91 , Issue 2 , October 1983 , pp. 319 - 328
Copyright
Copyright © Cambridge University Press 1983

References

REFERENCES

Barlow, D. F. (1972). The aerosol stability of a strain of foot-and-mouth disease virus and the effects on stability of precipitation with ammonium sulphate, methanol, or polyethylene glycol. Journal of General Virology 15, 17–24.CrossRefGoogle ScholarPubMed
Beard, C. W. & Easterday, B. C. (1965). An aerosol apparatus for the exposure of large and small animals: description and operating characteristics. American Journal of Veterinary Research 26, 174–182.Google ScholarPubMed
Burrows, R. (1968). Excretion of foot-and-mouth disease virus prior to the development of lesions. Veterinary Record 82, 387–388.Google Scholar
Donaldson, A. I. (1972). The influence of relative humidity on the aerosol stability of different strains of foot-and-mouth disease virus suspended in saliva. Journal of General Virology 15, 25–33.Google Scholar
Fogedby, E. G., Malmquist, W. A., Osteen, O. L. & Johnson, M. L. (1960). Air-borne transmission of foot-and-mouth disease virus. Nord. Veterinary Medicine 12, 490–498.Google Scholar
Graves, J. H., McVicar, J. W., Sutmoller, P. & Trautman, H. (1971). Contact transmission of foot-and-mouth disease from infected to susceptible cattle. Journal of Infectious Diseases 123, 386–391.CrossRefGoogle ScholarPubMed
Hatch, T. F. (1961). Distribution and deposition of inhaled particles in respiratory tract. Bacteriological Reviews 25, 237–240.CrossRefGoogle ScholarPubMed
Hatch, T. F. & Gross, P. (1964). Pulmonary deposition and retention of inhaled aerosols. New York, London: Academic Press.Google Scholar
Henderson, D. W. (1952). An apparatus for the study of airborne infection. Journal of Hygiene 50, 53–68.CrossRefGoogle Scholar
Hyslop, N. St. G. (1965). Airborne infection with the virus of foot-and-mouth disease. Journal of Comparative Pathology 75, 119–126.CrossRefGoogle ScholarPubMed
Jericho, K. W. F. & O'connell, D. C. (1974). Deposition in the respiratory tract of cattle of spores of Bacillus suhtilis var niger by inhalation and by the nasal instillation. Canadian Journal of Comparative Medicine 38, 260–264.Google Scholar
Knight, V. (1980). Viruses as agents of airborne contagion. Annals of the New York Academy of Sciences 353, 147–156.Google Scholar
Larson, E. W., Young, H. W. & Walker, J. S. (1976). Aerosol evaluations of the DeVilbiss no. 40 and vapenefrin nebulizers. Applied and Environmental Microbiology 31, 150–151.Google Scholar
Lillie, L. E. & Thompson, R. G. (1972). The pulmonary clearance of bacteria by calves and mice. Canadian Journal of Comparative Medicine 36, 129–137.Google ScholarPubMed
Lincoln, R. E., Hodges, D. R., Klein, F., Mahlandt, B. G., Jones, W. I., Haines, B. W., Rhian, M. A. & Walker, J. S. (1965). Role of the lymphatics in the pathogenesis of anthrax. Journal of Infectious Diseases 115, 481–494.CrossRefGoogle ScholarPubMed
Lloyd, L. C. & Etheridge, J. R. (1975). Experimental assessment of the proportion of airborne particles trapped in the upper respiratory tract of cattle. Victorian Veterinary Proceedings 33, 57.Google Scholar
May, K. R. (1966). Multistage liquid impinger. Bacteriological Reviews 30, 559–570.CrossRefGoogle ScholarPubMed
McKercher, P. D., Dellers, R. W., Giordano, A. R. (1966). Foot-and-mouth disease infection in cattle housed in an isolation unit. Cornell Veterinarian 56, 395–401.Google Scholar
McVicar, J. W. & Sutmoller, P. (1976). Growth of foot-and-mouth disease virus in the upper respiratory tract of non-immunized, vaccinated and recovered cattle after intranasal inoculation. Journal of Hygiene 76, 467–481.Google Scholar
Morrow, P. E. (1980). Physics of airborne particles and their deposition in the lung. Annals of the New York Academy of Sciences 353, 71–80.CrossRefGoogle ScholarPubMed
Palmer, F. & Kingsbury, S. S. (1952). Particle size in nebulized aerosols. American Journal of Pharmacy 124, 112–124.Google ScholarPubMed
Sellers, R. F. & Herniman, K. A. J. (1972). The effects of spraying on the amounts of airborne foot-and-mouth disease virus present in loose-boxes. Journal of Hygiene 70, 551–556.CrossRefGoogle ScholarPubMed
Sellers, R. F. & Parker, J. (1969). Airborne excretion of foot-and-mouth disease virus. Journal of Hygiene 67, 671–677.Google ScholarPubMed
Sellers, R. F., Donaldson, A. I. & Herniman, K. A. J. (1970). Inhalation, persistence and dispersal of foot-and-mouth disease virus by man. Journal of Hygiene 68, 565–573.Google Scholar
Sellers, R. F., Herniman, K. A. J. & Donaldson, A. I. (1971). The effect of killing or removal of animals affected with foot-and-mouth disease on the amounts of airborne virus present in looseboxes. British Veterinary Journal 127, 358–364.CrossRefGoogle ScholarPubMed
Sellers, R. F., Herniman, K. A. J. & Gumm, I. D. (1977). The airborne dispersal of foot-and-mouth disease virus from vaccinated and recovered pigs, cattle, and sheep after exposure to infection. Research in Veterinary Science 23, 70–75.Google Scholar
Sutmoller, P. & McVicar, J. W. (1976 a). Pathogenesis of foot-and-mouth disease: the lung as an additional portal of entry of the virus. Journal of Hygiene 77, 235–243.CrossRefGoogle ScholarPubMed
Sutmoller, P. & McVicar, J. W. (1976 b). Pathogenesis of foot-and-mouth disease: clearance of the virus from the circulation of cattle and goats during experimental viremia. Journal of Hygiene 77, 245–253.CrossRefGoogle Scholar