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Acute respiratory illness in the community. Frequency of illness and the agents involved

Published online by Cambridge University Press:  15 May 2009

A. S. Monto  and
K. M. Sullivan
A. S. Monto
Affiliation:
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor
K. M. Sullivan
Affiliation:
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor
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Investigations of respiratory illnesses and infections in Tecumseh. Michigan. USA, were carried out in two phases, together covering 11 years. During the second phase, there were 5363 person-years of observation. Respiratory illness rates in both males and females peaked in the 1–2 year age group and fell thereafter. Adult females had more frequent illnesses than adult males; illnesses were less common in working women than in women not working outside the home. Isolation of viruses fell with increasing age; rhinoviruses were the most common isolate. Influenza infection rates, determined serologically, suggested relative sparing of young children from infection with type A (H1N1) and type B. Infection rates were highest in adult age groups for type A (H3N2). The isolation and serological infection rates were used to estimate the extent to which laboratory procedures underestimated the proportion of respiratory illnesses caused by each infectious agent; data from other studies were also used in this estimation. Severity of respiratory illnesses was assessed by the proportion of such illnesses that resulted in consultation of a physician. Rhinoviruses produced the greatest number of consultations. Overall, physician consultations were associated with 25.4% of respiratory illnesses.

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 1 , February 1993 , pp. 145 - 160
Copyright
Copyright © Cambridge University Press 1993

References

REFERENCES

1.Colley, JRT. Respiratory disease in childhood. Brit Med Bull 1971; 27: 9–13.CrossRefGoogle ScholarPubMed
2.Monto, AS. Acute respiratory infection in children of developing countries: challenge of the 1990s. Rev Infect Dis 1989; 11: 498–505.CrossRefGoogle ScholarPubMed
3.United States Public Health Service: 1987 current estimates from the Health Interview Survey. United States –1986. US Department of Health. Education and Welfare: Series 10, No 1164.Google Scholar
4.Dingle, JH, Badger, GF, Jordan, WS. Illness in the home: A study of 25,000 illnesses in a group of Cleveland families. Cleveland: Case Western Reserve University Press, 1964.Google Scholar
5.Fox, JP. Is a rhinovirus vaccine possible? Am J Epidemiol 1976; 103: 345–54.CrossRefGoogle Scholar
6.Couch, RB. The common cold: control? J Infect Dis 1984; 150: 167–73.CrossRefGoogle ScholarPubMed
7.Tominack, RL, Hayden, FG. Rimantadine hydrochloride and amantadine hydrochloride use in influenza A infections. Inf Dis Clinics N America 1987; 1: 459–78.CrossRefGoogle Scholar
8.Hall, CB, McBride, JT, Walsh, EE. et al. Aerosolized ribavirin treatment of infants with respiratory syncytial viral infections. New Engl J Med 1983; 308: 1443–7.CrossRefGoogle Scholar
9.Monto, AS, Schwartz, SA, Albrecht, JK. Ineffectiveness of post exposure prophylaxis of rhinovirus infection with low-dose intranasal alpha 2b interferon in families. Antimicrob Agents Chemother 1983; 33: 387–90.CrossRefGoogle Scholar
10.Monto, AS, Napier, JA, Metzner, HL. The Tecumseh Study of respiratory illness: I. Plan of study and observations on syndromes of acute respiratory disease. Am J Epidemiol 1971; 94: 269–79.CrossRefGoogle ScholarPubMed
11.Monto, AS, Koopman, JS, Longini, IM Jr. Tecumseh study of illness: XIII. Influenza infection and disease 1976–81. Am J Epidemiol 1985; 121: 811–22.CrossRefGoogle Scholar
12.Monto, AS, Cavallaro, JJ. The Tecumseh study of respiratory illness. II. Patterns of occurrence of infection with respiratory pathogens. 1965–1969. Am J Epidemiol 1971; 94: 280–9.CrossRefGoogle ScholarPubMed
13.Monto, AS, Ohmit, S. Respiratory syncytial virus in a community population: Persistence of subgroups A and B since 1966. J Infect Dis 1990; 161: 781–3.CrossRefGoogle Scholar
14.Monto, AS, Bryan, ER, Ohmit, S. Rhinovirus infections in Tecumseh. Michigan: Illness frequency and number of serotypes. J Infect Dis 1987; 156: 43–9.CrossRefGoogle ScholarPubMed
15.Monto, AS, Lim, SK. The Tecumseh study of respiratory illness. VI. Frequency and relationship between outbreaks of coronavirus infection. J Infect Dis 1974; 129: 271–6.CrossRefGoogle ScholarPubMed
16.Monto, AS, Maassab, HF. Ether treatment of type B influenza virus antigen for the hemagglutination inhibition test. J Clin Microbiol 1981; 13: 54–7.CrossRefGoogle ScholarPubMed
17.Kendal, AP, Joseph, JM, Kobayashi, G. et al. Laboratory-based surveillance of influenza virus in the United States during the winter of 1977–1978. I. Periods of prevalence of H1N1 and H3N2 influenza A strains, their relative rates of isolation in different age groups, and detection of antigenic variants. Am J Epid 1979; 110: 449–61.CrossRefGoogle ScholarPubMed
18.Mathur, U, Bently, DW, Hall, CB, et al. Influenza A/Brazil/78 (H1N1) infection in the elderly. Am Rev Respir Dis 1981; 123: 633–5.Google Scholar
19.Monto, AS. The Tecumseh study of respiratory illness. V. Patterns of infection with the parainfluenza viruses. Am J Epidemiol 1973; 97: 338–48.CrossRefGoogle Scholar
20.Fox, JP, Cooney, MK, Hall, CE, et al. Influenza virus infections in Seattle families, 1975–1979. II. Pattern of infection in invaded households and relation of age and prior antibody to occurrence of infection and related illness. Am J Epidemiol 1982; 116: 228–43.CrossRefGoogle ScholarPubMed
21. Center for Disease Control. 1976 Influenza respiratory disease surveillance p. 10–11. Report no. 90. Public Health Service. Center for Disease Control, Atlanta, GA.Google Scholar
22.Hall, CB, Douglas, RG Jr. Clinically useful method for the isolation of respiratory syncytial virus. J Inf Dis 1975; 131: 1–5.CrossRefGoogle ScholarPubMed
23.Monto, AS, Ullman, BM. Acute respiratory illness in an American community: The Tecumseh study. JAMA 1974; 277: 164–9.CrossRefGoogle Scholar
24.Grayston, JT, Kuo, CC, Wang, SP, et al. A new Chamydia psittaci strain. TWAR. isolated in acute respiratory tract infections. N Engl J Med 1986; 315: 161–8.CrossRefGoogle Scholar
25.Larson, HE, Reed, SE, Tyrrell, DAJ. Isolation of rhinoviruses and coronaviruses from 38 colds in adults. J Med Virol 1980; 5: 221–9.CrossRefGoogle ScholarPubMed
26.Glezen, WP, Parades, A, Allison, JE, et al. Risk of respiratory syncytial virus infection for infants from low-income families in relationship to ages, sex, ethnic group and maternal antibody level. J Pediatrics 1981; 98: 708–15.CrossRefGoogle Scholar
27.McIntosh, K, Dees, JH, Becker, WB, et al. Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease. Proc Natl Acad Sci USA 1967; 57: 933–40.CrossRefGoogle ScholarPubMed
28.Tyrrell, DAJ, Bynoe, ML. Cultivation of viruses from a high proportion of patients with colds. Lancet 1966; 1: 76–7.CrossRefGoogle ScholarPubMed
29.McIntosh, K. Coronaviruses: a comparative review. Current topics in Microbiology and Immunology 1974; 63: 85–129.Google Scholar
30.Brimblecombe, FSW, Cruickshank, R, Masters, P, et al. Family studies of respiratory infections. Brit Med J 1958; 1: 119–28.CrossRefGoogle ScholarPubMed
31.Buck, C. Acute upper respiratory infections in families. Am J Hyg 1956; 63: 1–12.Google ScholarPubMed
32.Van Volkenburgh, VA, Frost, WH. Acute minor respiratory diseases prevailing in a group of families residing in Baltimore, Maryland, 1928–1930: Prevalence, distribution and clinical description of observed cases. Am J Hyg 1933; 17: 122–53.Google Scholar