Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-03T07:58:19.301Z Has data issue: false hasContentIssue false

Absence of epidemicity of severe leptospirosis in Barbados

Published online by Cambridge University Press:  15 May 2009

S. Bennett
Affiliation:
Tropical Health Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
C. O. R. Everard
Affiliation:
Leptospira Laboratory, Enmore 2, Lower Collymore Rock, St Michael, Barbados
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The possibility of micro-epidemics of severe leptospirosis occurring on the island of Barbados was investigated by examining the space-time clustering of the disease in 212 laboratory-confirmed cases admitted to Queen Elizabeth Hospital, Bridgetown, over a 7-year period. A series of 109 patients with symptoms compatible with leptospirosis but shown to be otherwise by laboratory examination were also examined for comparison. No significant space-time clustering was found among the leptospirosis cases, indicating no evidence for micro-epidemics. By comparison, statistically significant clustering was apparent among the smaller non-leptospirosis series. Possible explanations for the absence of observed micro-epidemics of leptospirosis are discussed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1991

References

1.Everard, COR, Maude, GH, Hayes, RJ.. Leptospiral infection: a household serosurvey in urban and rural communities in Barbados and Trinidad. Ann Trop Med Parasit 1990; 84: 255–66.CrossRefGoogle Scholar
2.Edwards, CN, Nicholson, GD, Hassell, TA, Everard, COR, Callender, J. Leptospirosis in Barbados – a clinical study. W I Med J 1990. In press.Google ScholarPubMed
3.Knox, G. Detection of low intensity epidemicity; application to cleft lip and palate. Br J Prev Soc Med 1963; 17: 121–7.Google ScholarPubMed
4.Pike, MC, Bull, D. Knox test for space-time clustering in epidemiology. Appl Statist 1974; 23: 92–5.CrossRefGoogle Scholar
5.Damude, DF, Jones, CJ, White, HStC, Myers, DM. The problem of human leptospirosis in Barbados. Trans Roy Soc Trop Med Hyg 1979; 73: 169–77.CrossRefGoogle ScholarPubMed
6.Johnson, RC. Leptospirosis. In: Warren, KS, Mahmoud, AAF, eds. Tropical and geographic medicine. New York: McGraw Hill, 1985: 839–43.Google Scholar
7.Everard, COR, Ferdinand, GA, Butcher, LV, Everard, JD. Leptospirosis in piggery workers on Trinidad. J Trop Med Hyg 1989; 92: 253–8.Google ScholarPubMed
8.Cacciapuoti, B, Cicerone, L, Maffei, C et al. , A water borne outbreak of leptospirosis. Am J Epid 1987; 126: 535–45.CrossRefGoogle Scholar
9.Ederer, F, Myers, MH, Mantel, N. A statistical problem in space and time: do leukaemia cases come in clusters? Biometrics 1964; 20: 626–38.CrossRefGoogle Scholar
10.David, FN, Barton, DE. Two space-time interaction tests for epidemicitv. Br J Prev Soc Med 1966; 20: 44–8.Google Scholar