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Possible effects of (trans)gene flow from crops on the genetic diversity from landraces and wild relatives

Published online by Cambridge University Press:  15 June 2003

Paul Gepts  and
Roberto Papa
Paul Gepts
Affiliation:
Department of Agronomy and Range Science, University of California, 1 Shields Avenue, Davis, CA 95616-8515, USA
Roberto Papa
Affiliation:
Dipartimento di Biotecnologie Agrarie ed Ambientali, Università Politecnia delle Marche, Via Brecce Bianche, 60131 Ancona, Italy

Abstract

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Gene flow is a potential concern associated with the use of transgenic crops because it could affect genetic diversity of related landraces and wild relatives. This concern has taken on added importance with the looming introduction of transgenic crops in centers of crop domestication (Mexico, China) and those producing pharmaceutical compounds. For gene flow to take place among cultivars and their wild relatives, several steps have to be fulfilled, including the presence of cultivars or wild relatives within pollen or seed dispersal range, the ability to produce viable and fertile hybrids, at least partial overlap in flowering time, actual gene flow by pollen or seed, and the establishment of crop genes in the domesticated or wild recipient populations. In contrast with domestication genes, which often make crops less adapted to natural ecosystems, transgenes frequently represent gains of function, which might release wild relatives from constraints that limit their fitness. In most sexually reproducing organisms, the chromosomal region affected by selection of a single gene amounts to a small percentage of the total genome size. Because of gene flow, the level of genetic diversity present in the domesticated gene pool becomes a crucial factor affecting the genetic diversity of the wild gene pool. For some crops, such as cotton and maize, the introduction of transgenic technologies has led to a consolidation of the seed industry and a reduction in the diversity of the elite crop gene pool. Thus, diversity in improved varieties grown by farmers needs to be monitored. Several areas deserve further study, such as the actual magnitude of gene flow and its determinants in different agroecosystems, the long-term effects of gene flow on genetic diversity both across gene pools and within genomes, the expression of transgenes in new genetic backgrounds, and the effects of socio-economic factors on genetic diversity.

Keywords

genetic diversitygene flowselectiondomesticationwild progenitorseed industrytransgene
Type
Research Article
Information
Environmental Biosafety Research , Volume 2 , Issue 2 , April 2003 , pp. 89 - 103
Copyright
© ISBR, EDP Sciences, 2003

References

Albagli S (2002) Implementation of the Convention on Biological Diversity in Brazil. In Encyclopedia of Life Supporting Systems (EOLSS), developed under the Auspices of the UNESCO. EOLSS Publishers, Oxford, UK
Bartsch, D, Ellstrand, NC (1999) Genetic evidence for the origin of Californian wild beets (genus Beta). Theor. Appl. Genet. 99: 1120-1130 CrossRef
Bartsch, D, Schmidt, M, Pohl-Orf, M, Haag, C, Schuphan, I (1996) Competitiveness of transgenic sugar beet resistant to beet necrotic yellow vein virus and potential impact on wild beet populations. Mol. Ecol. 5: 199-205 CrossRef
Bartsch, D, Lehnen, M, Clegg, J, Pohl-Orf, M, Schuphan, I, Ellstrand, NC (1999) Impact of gene flow from cultivated beet on genetic diversity of wild sea beet populations. Mol. Ecol. 8: 1733-1741 CrossRef
Bartsch, D, Brand, U, Morak, C, Pohl-Orf, M, Schuphan, I, Ellstrand, NC (2001) Biosafety of hybrids between transgenic virus-resistant sugar beet and Swiss chard. Ecol. Appl. 11: 142-147 CrossRef
Beets WC (1982) Multiple cropping and tropical farming systems. Westview Press, Aldershot, Hants, UK.
Bennett, MD, Leitch, IJ (1995) Nuclear, DNA amounts in angiosperms. Ann. Bot. 76: 113-176 CrossRef
Bergelson, J, Purrington, CB, Wichmann, G (1998) Promiscuity in transgenic plants. Nature 395: 25-25 CrossRef
Bronzini de Caraffa, V, Maury, J, Gambotti, C, Breton, C, Bervillé, A, Giannettini, J (2002) Mitochondrial, DNA variation and RAPD mark oleasters, olive and feral olive from Western and Eastern Mediterranean. Theor. Appl. Genet. 104: 1209-1216 CrossRef
Brown, SE, Severson, DW, Smith, LA, Knudson, DL (2001) Integration of the Aedes aegypti mosquito genetic linkage and physical maps. Genetics 157: 1299-1305
Brush, SB (1995) In situ conservation of landraces in centers of crop diversity. Crop Sci. 35: 346-354 CrossRef
Bulmer, MG (1972) Multiple niche polymorphism. Am. Nat. 106: 254-257 CrossRef
Charlesworth, B, Morgan, MT, Charlesworth, D (1993) The effects of deleterious mutations on neutral molecular variation. Genetics 134: 1289-1303
Charlesworth, D, Charlesworth, B, Morgan, MT (1995) The pattern of neutral molecular variation under the background selection model. Genetics 141: 1619-1632
Convention on Biological Diversity (1992) Convention text. http://www.biodiv.org/convention/articles.asp. (Accessed: May 4, 2003)
Cummings, MP, Clegg, MT (1998) Nucleotide sequence diversity at the alcohol dehydrogenase 1 locus in wild barley (Hordeum vulgare ssp. spontaneum) - an evaluation of the background selection hypothesis. Proc. Nat. Acad. Sci. USA 95: 5637-5642 CrossRef
Darwin C (1859) On the origin of species by means of natural selection. J. Murray, London
Debouck, DG, Toro, O, Paredes, OM, Johnson, WC, Gepts, P (1993) Genetic diversity and ecological distribution of Phaseolus vulgaris in northwestern South America. Econ. Bot. 47: 408-423 CrossRef
Delaney, DE, Bliss, FA (1991a) Selection for increased percentage phaseolin in common bean. 1. Comparison of selection for seed protein alleles and S1 family recurrent selection. Theor. Appl. Genet. 81: 301-305 CrossRef
Delaney, DE, Bliss, FA (1991b) Selection for increased percentage phaseolin in common bean. 2. Changes in frequency of seed protein alleles with S1 family recurrent selection. Theor. Appl. Genet. 81: 306-311 CrossRef
Delgado Salinas A, Bonet A, Gepts P (1988) The wild relative of Phaseolus vulgaris in Middle America. In Gepts P, ed, Genetic resources of Phaseolus beans. Kluwer, Dordrecht, the Netherlands, pp 163-184
Diamond vs. Chakrabarty (1980) 447 USA 303. United States Supreme Court. http://supct.law.cornell.edu/supct/cases/447 us303.htm. (Accessed: May 4, 2003)
Doebley J (1992) Molecular systematics and crop evolution. In Soltis PS, Soltis DE, Doyle JJ, eds, Molecular systematics of plants. Chapman Hall, New York, pp 202-222
Doebley, JF, Wendel, JD, Smith, JSC, Stuber, CW, Goodman, MM (1988) The origin of cornbelt maize: the isozyme evidence. Econ. Bot. 42: 120-131 CrossRef
Ellstrand, NC, Prentice, HC, Hancock, JF (1999) Gene flow and introgression from domesticated plants into their wild relatives. Annu. Rev. Ecol. Syst. 30: 539-563 CrossRef
Evans, MMS, Kermicle, JL (2001) Teosinte crossing barrier1, a locus governing hybridization of teosinte with maize. Theor. Appl. Genet. 103: 259-265 CrossRef
Fay, JC, Wu, CI (2000) Hitchhiking under positive Darwinian selection. Genetics 155: 1405-1413
Flint-Garcia, SA, Thornsberry, JM, Buckler, SE (2003) Structure of linkage disequilibrium in plants. Annu. Rev. Plant Biol. 54: 357-374 CrossRef
Francis, CA (1985) Variety development for multiple cropping systems. Crit. Rev. Plant Sci. 3: 133-168 CrossRef
Francis CA (1986) Multiple cropping systems. Macmillan, New York
Frey, KJ (1975) Plant breeding in the seventies: useful genes from wild plant species. Egypt. J. Genet. Cytol. 5: 460-482
Frey KJ (1996) National Plant Breeding Study. I. Human and financial resources devoted to plant breeding research and development in the United States in 1994. Ames, IA: Iowa State University
Freyre, R, Ríos, R, Guzmán, L, Debouck, DG, Gepts, P (1996) Ecogeographic distribution of Phaseolus spp. (Fabaceae) in Bolivia. Econ. Bot. 50: 195-215 CrossRef
Fulton M, Giannakas K (2001) Agricultural biotechnology and industry structure. AgBioForum 4: http://www.agbioforum.org/Default/vol4no2ar8fulton.htm. (Accessed: May 4, 2003)
Geffroy V, Sicard D, de Oliveira JCF, Sévignac M, Cohen S, Gepts P, Neema C, Dron M (1999) Identification of an ancestral resistance gene cluster involved in the coevolution process between Phaseolus vulgaris and its fungal pathogen Colletotrichum lindemuthianum. Mol. Plant Microbe In. 12: 774-784
Geffroy, V, Sévignac, M, De Oliveira, JCF, Fouilloux, G, Skroch, P, Thoquet, P, Gepts, P, Langin, T, Dron, M (2000) Inheritance of partial resistance against Colletotrichum lindemuthianum in Phaseolus vulgaris and co-localization of QTL with genes involved in specific resistance. Mol. Plant Microbe In. 13: 287-296 CrossRef
Gepts, P (1993) The use of molecular and biochemical markers in crop evolution studies. Evol. Biol. 27: 51-94
Gepts P (1995) Genetic markers and core collections. In Hodgkin T, Brown A, van Hintum TJL, Morales E, eds, Core collections of plant genetic resources. Wiley, New York, pp 127-146
Gepts P (2000) A phylogenetic and genomic analysis of crop germplasm: a necessary condition for its rational conservation and utilization. In Gustafson J, ed, Proc. Stadler Symposium, Plenum. New York, pp 163-181
Gepts P (2001) Origins of plant agriculture and major crop plants. In Tolba M, ed, Our fragile world: Challenges and opportunities for sustainable development. EOLSS Publishers, Oxford, pp 629-637
Gepts, P (2002) A comparison between crop domestication, classical plant breeding, and genetic engineering. Crop Sci. 42: 1780-1790 CrossRef
Gepts P (n.d.) Evolution of crop plants. agronomy.ucdavis.edu/ gepts/pb143/pb143.htm. (Accessed: May 4, 2003)
Goodman RM, Newell N (1985) Genetic engineering of plants for herbicide resistance: status and prospects. In Halvorson H, Pramer D, Rogul M, eds, Engineered organisms in the environment: scientific issues, American Society for Microbiology. Washington, D.C., pp 47-53
Hancock, JF, Grumet, R, Hokanson, SC (1996) The opportunity for escape of engineered genes from transgenic crops. HortScience 31: 1080-1085
Harlan, JR, de Wet, JMJ (1971) Towards a rational classification of cultivated plants. Taxon 20: 509-517 CrossRef
Hauser, TP, Shaw, RG, Østergård, H (1998a) Fitness of F1 hybrids between weedy Brassica rapa and oilseed rape (B. napus). Heredity 81: 429-435 CrossRef
Hauser, TP, Jørgensen, RB, Østergård, H (1998b) Fitness of backcross and F2 hybrids between weedy Brassica rapa and oilseed rape (B. napus). Heredity 81: 436-443 CrossRef
Haygood R, Ives AR, Andow DA (2003) Consequences of recurrent gene flow from crops to wild relatives. Proc. Royal Soc. London B, Biol Sci.: in press
Heywood VH, Watson RT, United Nations Environment Programme (1995) Global biodiversity assessment. Cambridge University Press, Cambridge
Huang J, Rozelle S, Pray C, Wang Q (2002) Plant biotechnology in China. Science 295: 674-676
Huxel, GR (1999) Rapid displacement of native species by invasive species: effects of hybridization. Biol. Conserv. 89: 143-152 CrossRef
Jenczewski, E, Ronfort, J, Chèvre, A-M (2003) Crop-to-wild gene flow, introgression and possible fitness effects of transgenes. Environ. Biosafety Res. 2: 9-24 CrossRef
Kalaitzandonakes N, Hayenga M (2000) Structural change in the biotechnology and seed industrial complex: Theory and evidence. In Lesser W, ed, Transitions in Agbiotech: Economics of Strategy and Policy, Food Marketing Policy Center. University of Connecticut, Storrs, CT
Kelly, JD, Kolkman, JM, Schneider, K (1998) Breeding for yield in dry bean (Phaseolus vulgaris L.). Euphytica 102: 343-356 CrossRef
Kisha, TJ, Diers, BW, Hoyt, JM, Sneller, CH (1998) Genetic diversity among soybean plant introductions and North American germplasm. Crop Sci. 38: 1669-1680 CrossRef
Koenig, R, Gepts, P (1989) Segregation and linkage of genes or seed proteins, isozymes, and morphological traits in common bean (Phaseolus vulgaris). J. Hered. 80: 455-459 CrossRef
Kohn, MH, Pelz, H-J, Wayne, RK (2000) Natural selection mapping of the warfarin-resistance gene. Proc. Nat. Acad. Sci. USA 97: 7911-7915 CrossRef
Lenormand, T (2002) Gene flow and the limits to natural selection. Trends Ecol. Evol. 17: 183-189 CrossRef
Li, ZL, Qiu, LJ, Thompson, JA, Welsh, MM, Nelson, RL (2001) Molecular genetic analysis of USA and Chinese soybean ancestral lines. Crop Sci. 41: 1330-1336 CrossRef
Linder, CR, Taha, I, Seiler, GJ, Snow, AA, Rieseberg, LH (1998) Long-term introgression of crop genes into wild sunflower populations. Theor. Appl. Genet. 96: 339-347 CrossRef
Loreau, M, Behera, N (1999) Phenotypic diversity and stability of ecosystem processes. Theor. Popul. Biol. 56: 29-47 CrossRef
Louette, D, Charrier, A, Berthaud, J (1997) In situ conservation of maize in mexico - genetic diversity and maize seed management in a traditional community. Econ. Bot. 51: 20-38 CrossRef
Marek, LF, Mudge, J, Darnielle, L, Grant, D, Hanson, N, Paz, M, Yan, HH, Denny, R, Larson, K, Foster-Hartnett, D, Cooper, A, Danesh, D, Larsen, D, Schmidt, T, Staggs, R, Crow, JA, Retzel, E, Young, ND, Shoemaker, RC (2001) Soybean genomic survey: BAC-end sequences near RFLP and SSR markers. Genome 44: 572-581 CrossRef
Martin, GB, Adams, MW (1987a) Landraces of Phaseolus vulgaris (Fabaceae) in northern Malawi. I. Regional variation. Econ. Bot. 41: 190-203 CrossRef
Martin, GB, Adams, MW (1987b) Landraces of Phaseolus vulgaris (Fabaceae) in northern Malawi. II. Generation and maintenance of variability. Econ. Bot. 41: 204-215 CrossRef
McKay, JK, Latta, RG (2002) Adaptive population divergence: markers, QTL and traits. Trends Ecol. Evol. 17: 285-291 CrossRef
Montes-Hernández, S, Eguiarte, LE (2002) Genetic structure and indirect estimates of gene flow in three taxa of Cucurbita (Cucurbitaceae) in western Mexico. Am. J. Bot. 89: 1156-1163 CrossRef
Nadal A (2000) The environmental and social impacts of economic liberalization on corn production in Mexico. WWF, Geneva and Oxfam, Oxford, UK
Nurminsky, DI, Nurminskaya, MV, De Aguiar, D, Hartl, DL (1998) Selective sweep of a newly evolved sperm-specific gene in Drosophila. Nature 396: 572-575 CrossRef
Osborn, TC, Blake, T, Gepts, P, Bliss, FA (1986) Bean arcelin. 2. Genetic variation, inheritance and linkage relationships of a novel seed protein of Phaseolus vulgaris. Theor. Appl. Genet. 71: 847-855 CrossRef
Osborn, TC, Alexander, DC, Sun, SSM, Cardona, C, Bliss, FA (1988) Insecticidal activity and lectin homology of arcelin seed protein. Science 240: 207-210 CrossRef
Pagiola S, Kellenberg J, Vidaeus L, Srivastava J (1998) Mainstreaming biodiversity in agricultural development. Finance Dev. March 1998: 38-41; http://www.worldbank. org/fandd/english/pdfs/0398/060398.pdf
Papa, R, Gepts, P (2003) Asymmetry of gene flow and differential geographical structure of molecular diversity in wild and domesticated common bean (Phaseolus vulgaris L.) from Mesoamerica. Theor. Appl. Genet. 106: 239-250 CrossRef
Quist, D, Chapela, IH (2001) Transgenic, DNA introgressed into traditional maize landraces in Oaxaca, Mexico. Nature 414: 541-543 CrossRef
Quist, D, Chapela, IH (2002) Biodiversity (Communications arising (reply)): Suspect evidence of transgenic contamination/Maize transgene results in Mexico are artefacts. Nature 416: 602-602 CrossRef
Rafalski, JA, Tingey, SV (1993) Genetic diagnostics in plant breeding - RAPDs, microsatellites and machines. Trends Genet. 9: 275-280 CrossRef
Reed, DH, Frankham, R (2001) How closely correlated are molecular and quantitative measures of genetic variation? A meta-analysis. Evolution 55: 1095-1103. CrossRef
Remington, DL, Thornsberry, JM, Matsuoka, Y, Wilson, LM, Whitt, SR, Doeblay, J, Kresovich, S, Goodman, MM, Buckler, ES (2001) Structure of linkage disequilibrium and phenotypic associations in the maize genome. Proc. Nat. Acad. Sci. USA 98: 11479-11484 CrossRef
Rick C (1982). The potential of exotic germplasm for tomato improvement. In Vasil I, Scowcroft W, Frey K, eds, Plant improvement and somatic cell genetics. Academic Press, New York, pp 1-42
Rieseberg, LH, Gerber, D (1995) Hybridization in the Catalina Island Mountain Mahogany (Cercocarpus traskiae): RAPD evidence. Conserv. Biol. 9: 199-203 CrossRef
Saxena, D, Stotzky, G (2001) Bt corn has a higher lignin content than non-Bt corn. Am. J. Bot. 88: 1704-1706 CrossRef
Schultheis, JR, Wehner, TC, Walters, SA (1997) Mixtures of cucumber cultigens affect yield in a multiple-harvest system. Hortscience 32: 1024-1027
Schünmann, PHD, Coia, G, Waterhouse, PM (2002) Biopharming the SimpliRED (TM) HIV diagnostic reagent in barley, potato and tobacco. Mol. Breeding 9: 113-121 CrossRef
Singh, SP, Nodari, R, Gepts, P (1991) Genetic diversity in cultivated common bean. I. Allozymes. Crop Sci. 31: 19-23 CrossRef
Singh, SP, Molina, A, Gepts, P (1995) Potential of wild common bean for seed yield improvement of cultivars in the tropics. Can. J. Plant Sci. 75: 807-813 CrossRef
Smith CW (1995) Crop production: evolution, history, and technology. Wiley, New York
Snow, AA (2002) Transgenic crops - why gene flow matters. Nature Biotechnol. 20: 542-542 CrossRef
Snow, AA, Moran-Palma, P, Rieseberg, LH, Wszelaki, A, Seiler, G (1998) Fecundity, phenology, and see dormancy of F1 wild-crop hybrids in sunflower (Helianthus annuus, Asteraceae). Am. J. Bot. 85: 794-801 CrossRef
Snow, A, Pilson, D, Rieseberg, L, Paulsen, M, Pleskac, N, Reagon, M, Wolf, D, Selboa, S (2003) A Bt transgene reduces herbivory and enhances fecundity in wild sunflowers. Ecol. App. 13: 279-286 CrossRef
Sonnante, G, Stockton, T, Nodari, RO, Becerra Velásquez, VL, Gepts, P (1994) Evolution of genetic diversity during the domestication of common-bean (Phaseolus vulgaris L.). Theor. Appl. Genet. 89: 629-635 CrossRef
Stalker, HT (1980) Utilization of wild species for crop improvement. Adv. Agron. 33: 111-147 CrossRef
Stewart, CN, All, JN, Raymer, PL, Ramachandran, S (1997) Increased fitness of transgenic insecticidal rapeseed under insect selection pressure. Mol. Ecol. 6: 773-779 CrossRef
Stoger, E, Vaquero, C, Torres, E, Sack, M, Nicholson, L, Drossard, J, Williams, S, Keen, D, Perrin, Y, Christou, P, Fischer, R (2000) Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies. Plant Mol. Biol. 42: 583-590 CrossRef
Tanksley, SD, McCouch, SR (1997) Seed banks and molecular maps: unlocking genetic potential from the wild. Science 277: 1063-1066 CrossRef
USDA - Agricultural Marketing Service (1999). Cotton varieties planted - 1999 crop, Agricultural Marketing Service, Memphis, TN, USA
van Tienderen, PH, de Haan, AA, van der Linden, CG, Vosman, B (2002) Biodiversity assessment using markers for ecologically important traits. Trends Ecol. Evol. 17: 577-582 CrossRef
Wang, R-L, Stec, A, Hey, J, Lukens, L, Doebley, J (1999) The limits of selection during maize domestication. Nature 398: 236-239
Wang, R-L, Stec, A, Hey, J, Lukens, L, Doebley, J (2001) correction: The limits of selection during maize domestication. Nature 410: 718 CrossRef
Warburton, ML, Xianchun, X, Crossa, J, Franco, J, Melchinger, AE, Frisch, M, Bohn, M, Hoisington, D (2002) Genetic characterization of CIMMYT inbred maize lines and open pollinated populations using large scale fingerprinting methods. Crop Sci 42: 1832-1840 CrossRef
Whitt, SR, Wilson, LM, Tenaillon, MI, Gaut, BS, Buckler, ES, (2002) Genetic diversity and selection in the maize starch pathway. Proc. Nat. Acad. Sci. USA 99: 12959-12962 CrossRef
Wolf, DE, Takebayashi, N, Rieseberg, LH (2001) Predicting the risk of extinction through hybridization. Conserv. Biol. 15: 1039-1053 CrossRef
Wood D, Lenné JM (1999) Agrobiodiversity: characterization, utilization, and management. New York, Wallingford, Oxon CABI Pub
Yan, GY, Chadee, DD, Severson, DW (1998) Evidence for genetic hitchhiking effect associated with insecticide resistance in Aedes aegypti. Genetics 148: 793-800
Yi, S, Charlesworth, B (2000) A selective sweep associated with a recent gene transposition in Drosophila miranda. Genetics 156: 1753-1763
Zane, L, Bargelloni, L, Patarnello, T (2002) Strategies for microsatellite isolation: a review. Mol. Ecol. 11: 1-16 CrossRef
Zhu, YY, Chen, HR, Fan, JH, Wang, YY, Li, Y, Chen, JB, Fan, JX, Yang, SS, Hu, LP, Leung, H, Mew, TW, Teng, PS, Wang, ZH, Mundt, CC (2000) Genetic diversity and disease control in rice. Nature 406: 718-722 CrossRef