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Maternal abuse history and reduced fetal heart rate variability: Abuse-related sleep disturbance is a mediator

Published online by Cambridge University Press:  20 October 2016

Hanna Gustafsson ,
Colleen Doyle ,
Michelle Gilchrist ,
Elizabeth Werner  and
Catherine Monk
Hanna Gustafsson*
Affiliation:
Columbia University Medical Center
Colleen Doyle
Affiliation:
University of Minnesota
Michelle Gilchrist
Affiliation:
DePaul University
Elizabeth Werner
Affiliation:
Columbia University Medical Center
Catherine Monk
Affiliation:
Columbia University Medical Center New York State Psychiatric Institute
*
Address correspondence and reprint requests to: Hanna Gustafsson, Columbia University Medical Center, 640 West 168th Street, PH1540, New York, NY 10032; E-mail: [email protected].
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Abstract

The consequences of childhood maltreatment are profound and long lasting. Not only does the victim of abuse suffer as a child, but there is mounting evidence that a history of maltreatment places the next generation at risk for significant psychopathology. Research identifies postnatal factors as affecting this intergenerational transmission of trauma. However, emerging evidence suggests that part of this risk may be transmitted before birth, passed on via abuse-related alterations in the in utero environment that are as yet largely unidentified. To date, no study has directly assessed the influence of pregnant women's abuse history on fetal neurobehavioral development, nor considered trauma-associated poor sleep quality as a mediator reflecting established physiological dysregulation. Using data from 262 pregnant adolescents (ages 14–19), a population at elevated risk for childhood maltreatment, the current study examined maternal emotional abuse history and sleep quality in relation to third-trimester fetal resting heart rate variability, an index of parasympathetic nervous system functioning. The results indicate that maternal emotional abuse history is indirectly associated with lower fetal heart rate variability via abuse-related sleep disturbances. These data demonstrate an association between maternal abuse histories and fetal development, showing that at least part of the intergenerational transmission of risk occurs during pregnancy.

Type
Regular Articles
Information
Development and Psychopathology , Volume 29 , Issue 3 , August 2017 , pp. 1023 - 1034
Copyright
Copyright © Cambridge University Press 2016 

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Footnotes

This research was supported by grants from the National Institute of Mental Health (R01MH077144 and R01MH093677) and by a postdoctoral fellowship in behavioral medicine awarded by the Herbert H. and Ruth S. Reiner fellowship fund.

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