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Effects of high-intensity training on monocarboxylate transporters in Thoroughbred horses

Published online by Cambridge University Press:  04 March 2010

Yu Kitaoka ,
Yuki Wakasugi ,
Daisuke Hoshino ,
Kazutaka Mukai ,
Atsushi Hiraga  and
Hideo Hatta
Yu Kitaoka
Affiliation:
Department of Life Sciences (Sports Science), The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo153-8902, Japan
Yuki Wakasugi
Affiliation:
Department of Life Sciences (Sports Science), The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo153-8902, Japan
Daisuke Hoshino
Affiliation:
Department of Life Sciences (Sports Science), The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo153-8902, Japan
Kazutaka Mukai
Affiliation:
Equine Research Institute, Japan Racing Association, 321-4 Tokami-cho, Utsunomiya City, Tochigi Prefecture320-0856, Japan
Atsushi Hiraga
Affiliation:
Equine Research Institute, Japan Racing Association, 321-4 Tokami-cho, Utsunomiya City, Tochigi Prefecture320-0856, Japan
Hideo Hatta*
Affiliation:
Department of Life Sciences (Sports Science), The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo153-8902, Japan
*
*Corresponding author: [email protected]
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Abstract

The aim of this study was to investigate the effect of high-intensity training on lactate transporters (monocarboxylate transporters (MCTs)) in Thoroughbred horses. Five Thoroughbreds (three males and two geldings; 3–10 years old; 478 ± 13 kg) ran at 100% maximal oxygen uptake (VO2max) for 1 min (3 days per week, 3 weeks) or 2 min (2 days per week, 4 weeks) on a treadmill for 7 weeks. VO2max and ability to sustain an incremental all-out test of maximal running were measured, and muscle samples were obtained from the gluteus medius muscle at rest before and after the training. The performance in the all-out test and VO2max were increased after the training. The protein content of MCT1 and MCT4 in the gluteus medius muscles was not significantly altered. However, MCT1 showed a relationship with the duration of maximal exercise after the training. The changes in MCT4 showed a relationship with the increase in exercise duration by the training. These results suggest that in Thoroughbreds, although the overall changes in MCT protein after endurance training are small, MCT1 and MCT4 can play important roles in the capacity to sustain maximal exercise.

Keywords

Thoroughbreds; high intensity trainingexercise capacitylactateMCT1MCT4
Type
Research Paper
Information
Comparative Exercise Physiology , Volume 6 , Issue 4 , November 2009 , pp. 171 - 175
Copyright
Copyright © Cambridge University Press 2010

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