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The Effects of Testosterone on Cognition in Elderly Men: A Review

Published online by Cambridge University Press:  07 November 2014

Matthew F. Warren ,
Michael J. Serby  and
David M. Roane
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Abstract

In this article, the literature examining the relationship between testosterone and various cognitive domains in elderly men is reviewed. The review focuses on the role of endogenous testosterone levels and the effects of androgen depletion and replacement. The cognitive domains most commonly linked to testosterone include memory and visuospatial function. Indeed, the literature suggests that in certain conditions (ie, hypogonadism, cognitive impairment) testosterone levels may be significantly associated with memory and visuospatial function, but not other cognitive functions. Studies with larger sample sizes and more sensitive cognitive measures are indicated, as questions remain about the potential role of testosterone as a cognitive enhancer.

Type
Review Article
Information
CNS Spectrums , Volume 13 , Issue 10 , October 2008 , pp. 887 - 897
Copyright
Copyright © Cambridge University Press 2008

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