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Thiamine deficiency mimicking acute rejection following cardiac transplantation

Published online by Cambridge University Press:  19 August 2008

Andrew R. Gennery*
Affiliation:
Department of Paediatric Cardiology, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
Kim Bartlett
Affiliation:
Department of Child Health, The Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK
Asif Hasan
Affiliation:
Department of Child Health, The Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK
*
Dr Andrew Gennery Department of Paediatric Cardiology, Freeman Hospital, High Heaton, Newcastle upon TyneUK Tel: 0191 2843111; Fax: 0191 2132167

Abstract

We describe a recipient of an orthotopic cardiac transplant who developed severe ventricular dysfunction following an episode of sepsis. He had normal cardiac biopsies and responded to treatment with thiamine. Causes other than rejection should be considered in patients who have received a cardiac transplant and who present in cardiac failure.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 1998

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References

1. McIntyre, N, Stanley, NNCardiac Beriberi: Two modes of presentation. BMJ 1971;3: 567–569.CrossRefGoogle ScholarPubMed
2. Seear, M, Lockitch, G, Jacobson, B, Quigley, G, MacNab, A. Thiamine, riboflavin, and pyridoxine deficiencies in a population of critically ill children. J Pediatr 1992;121; 533538CrossRefGoogle Scholar
3. Barrett, TG, Forsyth, JM, Nathavitharana, KA, Booth, IW. Potentially lethal thiamine deficiency complicating parenteral nutrition in children. Lancet 1993;341: 901CrossRefGoogle ScholarPubMed
4. Orlot, D, Wood, C, Gothesman, R, Huault, G. Severe lactic acidosis related to acute thiamine deficiency. J Parent Enteral Nutr 1991;15: 105109.Google Scholar
5. Seligman, H, Halkin, H, Rauchfleisch, S, Kaufmann, N, Tal, R, Motro, M, Vered, Z, Ezra, D. Thiamine deficiency in patients with congestive heart failure receiving long term furosemide therapy: A pilot study. Am J Med 1991;91:151155.CrossRefGoogle Scholar