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Tetralogy of Fallot in a neonate following intrauterine exposure to valproic acid

Published online by Cambridge University Press:  19 August 2008

Wendy A. Stewart  and
R. Michael Giuffre
Wendy A. Stewart
Affiliation:
Division of Pediatric Cardiology, Alberta Children's Hospital, University of Calgary, Calgary
R. Michael Giuffre*
Affiliation:
Division of Pediatric Cardiology, Alberta Children's Hospital, University of Calgary, Calgary
*
Dr. Michael Giuffre, Pediatric Cardiologist, Alberta Children's Hospital, 1820 Richmond Rd, S.W., Calgary, Alberta, Canada T2T 5C7. Tel. 403 229 7211; Fax 403 229 7221.
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Summary

Valproic acid is a known teratogen, giving rise to a typical craniofacial appearance, the fetal valproate syndrome. Congenital heart malformations in this syndrome have most commonly been ventricular septal defects. We report a child with familial craniosynostosis, and tetralogy of Fallot, following intrauterine exposure to valproic acid.

Keywords

Tetralogy of Fallotvalproic acidteratogen
Type
Brief Reports
Information
Cardiology in the Young , Volume 6 , Issue 3 , July 1996 , pp. 232 - 234
Copyright
Copyright © Cambridge University Press 1996

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