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Severe hypertriglyceridemia associated with everolimus drug-eluting stent placement in an infant

Part of: Interventional Cardiology

Published online by Cambridge University Press:  08 April 2019

Kuan-Chi Lai Open the ORCID record for Kuan-Chi Lai [Opens in a new window] ,
Julie A. Brothers  and
Jason Z. Stoller
Kuan-Chi Lai
Affiliation:
Division of Neonatology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Julie A. Brothers
Affiliation:
Division of Cardiology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Jason Z. Stoller*
Affiliation:
Division of Neonatology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
*
Author for correspondence: Jason Z. Stoller, Children’s Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104, USA. Tel: 215-590-1653; Fax: 215-590-3051; E-mail: [email protected]
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Abstract

We report a case of severe hypertriglyceridemia associated with an everolimus drug-eluting stent in an infant with pulmonary vein stenosis. We review from current literature the mechanisms by which everolimus may cause dyslipidaemia, pharmacokinetics of everolimus in drug-eluting stents, and treatments of hypertriglyceridemia. This case demonstrates the need to closely monitor serum triglyceride levels after everolimus drug-eluting stent placement in infants.

Keywords

Catheterisationdrug-eluting stentpaediatricsdyslipidaemia
Type
Brief Report
Information
Cardiology in the Young , Volume 29 , Issue 4 , April 2019 , pp. 541 - 543
Copyright
© Cambridge University Press 2019 

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