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Reversible cardiomyopathy subsequent to perinatal infection with the human immunodeficiency virus

Published online by Cambridge University Press:  24 May 2005

Maria Suely Bezerra Diógenes ,
Antonio Carlos Camargo Carvalho  and
Regina Célia de Menezes Succi
Maria Suely Bezerra Diógenes
Affiliation:
Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Antonio Carlos Camargo Carvalho
Affiliation:
Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Regina Célia de Menezes Succi
Affiliation:
Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
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Abstract

We describe a patient with advanced perinatal acquired immunodeficiency syndrome who had early clinical manifestation of severe dilated cardiomyopathy with congestive heart failure. The picture was completely reversed after six years treatment and follow-up, and the child is now doing well at the age of seven, with normal left ventricular dimension and contractility as shown by echodopplercardiography. To the best of our knowledge, this is the first reported case of full recovery from cardiomyopathy in children with perinatally acquired infection by the human immunodeficiency virus.

Keywords

Human immunodeficiency virusperinatalcardiomyopathyechodopplercardiogram
Type
Brief Report
Information
Cardiology in the Young , Volume 13 , Issue 4 , August 2003 , pp. 373 - 376
Copyright
© 2003 Cambridge University Press

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References

Luginbuhl LM, Orav EJ, McIntosh K, Lipshultz SE. Cardiac morbidity and related mortality in children with HIV infection. JAMA 1993; 269: 2869–2875.Google Scholar
Herdy GVH, Lopes MM, Pinto CAM, et al. Alterações cardíacas em crianças com SIDA. Arq Bras Cardiol 1997; 68: 273–277.Google Scholar
Lipshultz SE, Bancroft EA, Boller A-M. Cardiovascular manifestation of HIV infection in children. In: Pizzo P, Wilfert CM (eds). Pediatric AIDS – The Challenge of HIV Infection in Infants, Children, and Adolescents, 3rd edn. Williams & Wilkins, Philadelphia, Baltimore, New York, 1998a, pp 335–361.
Lipshultz SE, Easley KA, Orav EJ, et al. Left ventricular structure and function in children infected with human immunodeficiency virus – The prospective P2C2 HIV multicenter study. Circulation 1998b; 97: 1246–1256.Google Scholar
De Castro S, D'Amati G, Gallo P, et al. Frequency and development of acute global left ventricular dysfunction in human immunodeficiency virus infection. J Am Coll Cardiol 1994; 24: 1018–1024.Google Scholar
Fingerhood M. Full recovery from severe dilated cardiomyopathy in an HIV-infected patient. The AIDS Reader 2001; 11: 333–335.Google Scholar
Centers for Disease Control. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR 1994; 43: 1–19.
European Collaborative Study. Natural history of vertically acquired human immunodeficiency virus-1 infection. Pediatrics 1994; 94: 815–819.
Barbaro G, Lorenzo G, Grisorio B, Barbarini G. Incidence of dilated cardiomyopathy and detection of HIV in myocardial cells of HIV-positive patients. New Engl J Med 1998; 339: 1093–1099.Google Scholar
Herskowitz A, Willoughby S, Wu T-C, et al. Immunopathogenesis of HIV-1-associated cardiomyopathy. Clin Immunopathol 1993; 68: 234–241.Google Scholar