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Progressive disease of the atrioventricular condution axis in an infant of an anti-Ro positive mother

Published online by Cambridge University Press:  19 August 2008

Orhan Uzun  and
John L. Gibbs
Orhan Uzun*
Affiliation:
Specialist Registrar in Paediatric Cardiology, Yorkshire Heart Centre, Leeds, UK
John L. Gibbs
Affiliation:
Consultant Paediatric Cardiologist, The Department of Paediatric Cardiology, Yorkshire Heart Centre, Leeds, UK
*
Dr O Uzun, Department of Paediatric Cardiology, Yorkshire Heart Centre E Floor, Leeds General Infinnary, Great George Street, Leeds LS 1 3EX, UK. Tel: 0113 3925748; Fax: 0113 3925784
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Abstract

A child of a mother with maternal anti-Ro and anti-La antibodies presented antenatally with abnormal myocardial function, and was found to have a first degree heart block at birth. The extent of the abnormality in the conduction system progressed, with appearance of left bundle branch block in addition to further prolongation of PR interval. A pacemaker was implanted prophylactically, but patient has remained well, with no further deterioration in her atrioventricular conduction.

Keywords

Anti-Rocongenital heart blockleft bundle block
Type
Brief Reports
Information
Cardiology in the Young , Volume 9 , Issue 2 , March 1999 , pp. 192 - 193
Copyright
Copyright © Cambridge University Press 1999

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References

1.Ramsey, Goldman R, Horn, D, Deng, J-S, Ziegler, GC, Kahl, LE, Steen, VD, La Porte, RE, Medsger, TA Jr. Anti, SSA. antibodies and fetal outcome in maternal systemic lupus crythematosus. Arthritis and Rheum 1986; 29: 1269–1273.CrossRefGoogle Scholar
2.Pinsky, WW, Gilette, PC, Garson, A Jr, McNamara, DG. Diagnosis, management, and long tenn results of patients with congenital complete atrioventricular block. Pediatrics 1982; 69: 728–733.CrossRefGoogle Scholar
3.Frohn-Mulder, IM, Meilof, JF, Szatmari, A, Stewrt, PASwaak, TJ, Hess, J. Clinical significance of maternal anti-Ro/SS-A antibodies in children with isolated heart block. J Am Coll Cardiol 1994; 23: 1677–1681.CrossRefGoogle ScholarPubMed
4.Geggel, RL, Tuker, L, Szer, I. Postnatal progression from secon-to third-degree heart block in nconatal lupus syndrome. J Pediatr 1988; 133: 1049–1052.CrossRefGoogle Scholar
5.Scott, JS, Maddison, PJ, Taylor, PV, Esscher, E, Scott, O, Skinner, RP. Connective-tissuse disease, antibodies to riboncleoprotein, and congenital heart block. N Engl J Med 1983; 309: 209–212.CrossRefGoogle Scholar