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Primary pediatric cardiac tumors: a 17 year experience

Published online by Cambridge University Press:  19 August 2008

Denver Sallee ,
Michael L. Spector ,
Daniel W. van Heeckeren  and
Chandrakant R. Patel
Denver Sallee
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, and the Department of Cardiothoracic Surgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Michael L. Spector
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, and the Department of Cardiothoracic Surgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Daniel W. van Heeckeren
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, and the Department of Cardiothoracic Surgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Chandrakant R. Patel*
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, and the Department of Cardiothoracic Surgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA
*
Chandrakant R. Patel, M.B.,B.S., Rainbow Babies and Childrens Hospital Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA. Tel: (216) 844-3275; Fax: (216) 844-5478
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Abstract

We reviewed 22 cases of primary pediatric cardiac tumors followed at our institution from January 1981 through November 1997, analyzing them by subtype, age and manner of presentation, location, associated findings, interventions, and clinical course. Rhabdomyomas were the most common (11), followed by intrapericardial teratomas (2), myxomas (1), fibromas (1), hemangiomas (1), mesotheliomas (1), and rhabdomyosarcomas (1), with 4 undetermined tumors. The majority (77%) of tumors were diagnosed before the age of one year, including six prenatally. The most common presentations were murmurs (5), arrhythmias (5), and abnormal screening fetal ultrasound examinations (4). Tumors were located most frequently in the right ventricle (13) and left ventricle (7), with multiple tumors being present in 10 cases. Eight patients (36%) had associated arrhythmias or conduction abnormalities, and of the 11 patients with rhabdomyomas, tuberous sclerosis was diagnosed in 8. Eight patients underwent cardiac catheterization, including two for electrophysiologic study with radiofrequency ablation, and seven patients had complete or partial tumor resection. The follow-up period ranged from 2 months to 15 years, and there were 3 tumor-related deaths. Therefore, despite the benign histology of most primary pediatric cardiac tumors, there may be significant associated morbidity and occasional mortality. As echocardiographic techniques such as fetal ultrasonography have continued to improve, however, these cardiac tumors have increasingly been detected early before significant symptoms develop.

Keywords

cardiac tumorschildhoodtuberous sclerosis
Type
Original Articles
Information
Cardiology in the Young , Volume 9 , Issue 2 , March 1999 , pp. 155 - 162
Copyright
Copyright © Cambridge University Press 1999

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