Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-24T23:10:25.237Z Has data issue: false hasContentIssue false

Outcome of the construction of a Blalock–Taussig shunt in adolescents and adults

Published online by Cambridge University Press:  13 July 2005

Aubrey Peries
Affiliation:
Royal Brompton and Harefield NHS Trust, London, United Kingdom
Amira A. A. Al-Hay
Affiliation:
Royal Brompton and Harefield NHS Trust, London, United Kingdom
Elliot A. Shinebourne
Affiliation:
Royal Brompton and Harefield NHS Trust, London, United Kingdom

Abstract

Aims: The purpose of our study was to ascertain the outcome of the construction of a Blalock–Taussig shunt in patients aged 12 years and over. Patients and methods: We identified 21 patients in whom a Blalock–Taussig shunt had been constructed subsequent to the age of 12 years. Of the patients, 9 were female, and their median age was 18.5 years, with a range from 12 to 46 years. All had usual atrial arrangement, and the atrioventricular connections were concordant in 11, with univentricular atrioventricular connection in 10. Pulmonary atresia was present in 8 (38 per cent), and pulmonary stenosis, either valvar or subvalvar, in 13. An interposition graft had been placed between the subclavian and pulmonary arteries in 16 patients, and an end-to-side anastomosis between the arteries in 5. Results: One patient had died in hospital, while 4 patients had died during the period of follow-up after initial construction of the shunt. Long-term follow-up was available in 86 per cent of patients. In the 3 patients lost to follow-up, the shunt had been known to be functioning at periods of 4, 8, and 10 years, respectively. Actuarial freedom from death after a period of 17 years was 76 per cent. In 8 patients, a period of 10 years had elapsed with the shunt patent, and a further 10 had a patent shunt after 5 years follow-up. Symptomatic improvement was reported in 16 (76 per cent) patients, although adverse cardiac events had occurred during follow-up in 17, including congestive heart failure in 3, atrial fibrillation in 3, and endocarditis in 2. In 2 patients, it had been possible to proceed to biventricular repair, one with tetralogy of Fallot, and the other having a Rastelli procedure. Further in 3 patients, it had been possible to construct the Fontan circulation, or one of its variants. One patient has undergone cardiac transplantation, while 2 are awaiting transplantation. Conclusions: Symptomatic improvement can be achieved by construction of a Blalock–Taussig shunt in older subjects, and the risks of surgery are low. Later repair may be feasible in some patients, but adverse cardiac events may follow the increased volume load on the systemic ventricle.

Type
Original Article
Copyright
© 2005 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Blalock A, Taussig HB. The surgical correction of malformations in which there is pulmonary stenosis or pulmonary atresia. JAMA 1945; 128: 189202.Google Scholar
McKay R, de Laval MR, Rees P, Taylor JF, Macartney FJ, Stark J. Assessment of Modified Blalock Taussig shunts using Expanded Polytetrafluoroethylene (Gortex). Ann Thorac Surg 1980; 30: 137145.Google Scholar
De Leval MR, McKay R, Jones M, Stark J, Macartney FJ. Modified Blalock–Taussig shunts. J Thorac Cardiovasc Surg 1981; 81: 112119.Google Scholar
Donahoo JS, Gardner TJ, Zahka K, Langford Kidd BS. Systemic pulmonary shunts in neonates and infants using microporous expanded polytetrafluoroethylene: immediate and late results. Ann Thorac Surg 1980; 30: 146150.Google Scholar
Di Benedetto G, Tiraboschi R, Vanini V, Annecchino P, Gamba A, Parenzan L. Systemic pulmonary artery shunt using PTFE prosthesis (Gortex). Early results and long term follow up on 105 consecutive cases. Thorac Cardiovasc Surg 1981; 29: 143147.Google Scholar
Grunkemeier GL, Starr A. Actuarial analysis of surgical results: rationale and method. Ann Thorac Surg 1977; 24: 404408.Google Scholar
Jahangiri M, Lincoln C, Shinebourne E. Does the modified Blalock Taussig shunt cause growth of the contralateral pulmonary artery? Ann Thorac Surg 1999; 67: 13971399.Google Scholar
Honda J. Growth of pulmonary arteries and morphological assessment after Blalock Taussig shunts. Nippon Kyobu Geka Gakkai Zasshi. J Jpn Assoc Thorac Surg 1993; 41: 569577.Google Scholar
Hofschire PJ, Rosenquist GC, Ruckerman RN, Moller JH, Edwards JF. Pulmonary vascular disease complicating the Blalock Taussig anastomosis. Circulation 1972; 56: 124126.Google Scholar
Fontan F, Kirklin JW, Fernandez G, et al. Outcome after “perfect” Fontan operation. Circulation 1990; 81: 15201536.Google Scholar
Mair DD, Hagler DJ, Puga FJ, Schaff HV, Danielson GK. Fontan operation in 176 patients with tricuspid atresia. Results and a proposed new index for patient selection. Circulation 1990; 82 (Suppl 5): 164169.Google Scholar
Driscoll DJ, Offord KP, Feldt RH, Schaff HV, Puga FJ, Danielson GK. Five to fifteen year follow-up after Fontan procedure. Circulation 1992; 85: 469496.Google Scholar
Hofbeck M, Singer H, Scharf J, et al. Total cavopulmonary anastomosis: selection criteria related to postoperative results. Thorac Cardiovasc Surg 1993; 41: 2833.Google Scholar
Cecchin F, Johnstrude CL, Perry JC, Friedman RA. Effect of age and surgical technique on symptomatic arrhythmias after the Fontan procedure. Am J Cardiol 1995; 76: 386391.Google Scholar
Cromme-Dijkhuis AH, Hess J, Hahlen K, et al. Specific sequelae after Fontan operation at mid and long term follow up. Arrhythmia, liver dysfunction and coagulation disorders. J Thorac Cardiovasc Surg 1993; 106: 11261132.Google Scholar
Cromme-Dijkhuis AH, Henkens CM, Bijleveld CM, Hillege HL, Bom VJ, van der Meer J. Coagulation factor abnormalities as possible thrombotic risk factors after Fontan operations. Lancet 1990; 336: 10871090.Google Scholar
Jahangiri M, Shore D, Kakkar V, Lincoln C, Shinebourne E. Coagulation factor abnormalities following the Fontan procedure and its modifications. J Thorac Cardiovasc Surg 1977; 113: 989992.Google Scholar
Du Plessis AJ, Chang AC, Wessel DL, et al. Cerebrovascular accidents following Fontan operation. Paediatr Neurol 1995; 12: 230236.Google Scholar
Mertens L, Hagler DJ, Sauer U, Somerville J, Gewillig M. Protein-losing enteropathy after the Fontan operation: an international multicenter study. J Thorac Cardiovasc Surg 1998; 115: 10631073.Google Scholar
Gatzoulis MA, Munk MD, Williams WG, Webb GD. Definitive palliation with cavopulmonary or aortopulmonary shunts for adults with single ventricle physiology. Heart 2000; 83: 5157.Google Scholar