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Lacosamide-induced atrial tachycardia in a child with hypoplastic left-heart syndrome: the importance of assessing additional proarrhythmic risks

Published online by Cambridge University Press:  21 July 2014

Rohit S. Loomba ,
Anoop K. Singh ,
Joshua Kovach  and
Todd M. Gudausky
Rohit S. Loomba*
Affiliation:
Department of Cardiology, Children’s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
Anoop K. Singh
Affiliation:
Department of Cardiology, Children’s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
Joshua Kovach
Affiliation:
Department of Cardiology, Children’s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
Todd M. Gudausky
Affiliation:
Department of Cardiology, Children’s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
*
Correspondence to: Department of Cardiology, Children’s Hospital of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI 53226, United States of America. Tel: 414-266-2600; Fax: 414-266-8517; E-mail: [email protected]
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Abstract

Antiepileptic medications have been reported to cause disturbances in cardiac conduction. Lacosamide decreases seizure burden by modulating sodium channels. Although it has been demonstrated to have few side effects, there have been reports of clinically significant cardiac conduction disturbances. We report the case of a child with hypoplastic left-heart syndrome and well-controlled multifocal atrial tachycardia who developed haemodynamically significant atrial tachycardia after receiving two doses of lacosamide.

Keywords

Lacosamideatrial tachycardiavimpatflecainide
Type
Brief Reports
Information
Cardiology in the Young , Volume 25 , Issue 4 , April 2015 , pp. 806 - 809
Copyright
© Cambridge University Press 2014 

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