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Is sudden cardiac death predictable in LEOPARD syndrome?

Published online by Cambridge University Press:  20 November 2006

Giuseppe Limongelli ,
Giuseppe Pacileo  and
Raffaele Calabrò
Giuseppe Limongelli
Affiliation:
Pediatric Cardiology, Monaldi Hospital, Second University of Naples, Naples, Italy
Giuseppe Pacileo
Affiliation:
Pediatric Cardiology, Monaldi Hospital, Second University of Naples, Naples, Italy
Raffaele Calabrò
Affiliation:
Pediatric Cardiology, Monaldi Hospital, Second University of Naples, Naples, Italy
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Abstract

We report the sudden cardiac death of a young male presenting with classic clinical features of LEOPARD syndrome, shown to be due to a mutation in the PTPN11 gene, and severe non obstructive hypertrophic cardiomyopathy. We also discuss briefly the usefulness of prophylactic risk stratification in patients with syndromic and non syndromic hypertrophic cardiomyopathy.

Keywords

Hypertrophic cardiomyopathyPTPN11 generisk stratification
Type
Brief Report
Information
Cardiology in the Young , Volume 16 , Issue 6 , December 2006 , pp. 599 - 601
Copyright
© 2006 Cambridge University Press

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