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Complete closure of the ductus arteriosus in the foetus with transposition of the great arteries

Published online by Cambridge University Press:  24 March 2020

Agnieszka Grzyb Open the ORCID record for Agnieszka Grzyb [Opens in a new window] ,
Adam Koleśnik ,
Dariusz Gruszfeld  and
Joanna Szymkiewicz-Dangel
Agnieszka Grzyb
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland Department of Cardiology, The Children’s Memorial Health Institute, Warsaw, Poland
Adam Koleśnik
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland Department of Cardiology, The Children’s Memorial Health Institute, Warsaw, Poland Cardiovascular Interventions Laboratory, The Children’s Memorial Health Institute, Warsaw, Poland
Dariusz Gruszfeld
Affiliation:
Department of Neonatology and Neonatal Intensive Care, The Children’s Memorial Health Institute, Warsaw, Poland
Joanna Szymkiewicz-Dangel*
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland
*
Author for correspondence: J. Szymkiewicz-Dangel, Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Agatowa 10, 03-680Warsaw, Poland. Tel: +48 22 510 26 08; Fax: +48 22 678 99 32. E-mail: [email protected]
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Abstract

Prenatal restriction of the ductus arteriosus can manifest as persistent pulmonary hypertension in the newborn, especially dangerous with the transposition of the great arteries. Its aetiology has long been related to maternal intake of non-steroidal anti-inflammatory drugs; however, some other substances, including polyphenols, may have similar properties. We describe a case of complete prenatal closure of the ductus arteriosus in the foetus with transposition of the great arteries. The newborn presented with pulmonary hypertension unresponsive to pharmacotherapy and died of multi-organ failure.

Keywords

Transposition of the great arteriesductus arteriosuspulmonary hypertensionfoetal medicineprenatal diagnosis
Type
Brief Report
Information
Cardiology in the Young , Volume 30 , Issue 4 , April 2020 , pp. 588 - 590
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

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