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A case of long QT syndrome associated with familial occurrence of persistent patency of the arterial duct

Published online by Cambridge University Press:  03 May 2005

Subramanian Jothi Murugan ,
Jonathan M. Parsons  and
Chris Bennett
Subramanian Jothi Murugan
Affiliation:
Department of Congenital Heart Disease and Clinical Genetics, Leeds General Infirmary, Leeds, United Kingdom
Jonathan M. Parsons
Affiliation:
Department of Congenital Heart Disease and Clinical Genetics, Leeds General Infirmary, Leeds, United Kingdom
Chris Bennett
Affiliation:
Department of Congenital Heart Disease and Clinical Genetics, Leeds General Infirmary, Leeds, United Kingdom
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Abstract

We describe an occurrence of long QT syndrome in association with persistent patency of the arterial duct in members of a family. Patency of the arterial duct was diagnosed in family members of 4 successive generations. The index case had long QT syndrome associated with such a patent duct. Another patient had long QT syndrome, but associated with a ventricular septal defect. We postulate that there may be a common genetic mechanism for long QT syndrome and persistent patency of the arterial duct.

Keywords

Arrhythmiasductus arteriosusgenetics
Type
Brief Report
Information
Cardiology in the Young , Volume 15 , Issue 3 , June 2005 , pp. 309 - 311
Copyright
© 2005 Cambridge University Press

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