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An infant case of coronary artery aneurysms with no systemic symptoms after treatment for Kawasaki disease

Published online by Cambridge University Press:  05 November 2024

Yumiko Asai ,
Takanori Suzuki Open the ORCID record for Takanori Suzuki [Opens in a new window]  and
Midori Yamada
Yumiko Asai
Affiliation:
Department of Pediatrics, Kariya Toyota General Hospital, Kariya, Aichi, Japan
Takanori Suzuki*
Affiliation:
Department of Pediatrics, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan
Midori Yamada
Affiliation:
Department of Pediatrics, Kariya Toyota General Hospital, Kariya, Aichi, Japan
*
Corresponding author: T. Suzuki; Email: [email protected]
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Abstract

This case is a 4-month-old patient with Kawasaki disease who showed coronary artery lesions after a disease relapse. Following the guidelines from the Randomised Controlled Trial to Assess Immunoglobulin plus Steroid Efficacy, the patient initially saw an improvement in symptoms. However, a relapse occurred despite low levels of C-reactive protein, leading to significant coronary artery growth. Treatment with a third dose of intravenous immunoglobulin and cyclosporine led to a slow reduction in the size of the coronary artery abnormalities. This case highlights the difficulty in monitoring Kawasaki disease progression through clinical symptoms and C-reactive protein levels alone. We also emphasise the necessity of echocardiographic monitoring in patients receiving anti-inflammatory treatments, including steroids, because coronary artery problems can arise or continue without the usual signs of Kawasaki disease or increased C-reactive protein levels.

Keywords

Kawasaki diseasecoronary artery abnormalitiesinfant
Type
Brief Report
Information
Cardiology in the Young , Volume 34 , Issue 9 , September 2024 , pp. 2007 - 2009
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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