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The systemic delivery and consumption of oxygen in the infant after cardiac surgery

Published online by Cambridge University Press:  13 October 2006

Daniel J. Penny
Daniel J. Penny
Affiliation:
The Department of Cardiology, The Royal Children's Hospital, The Murdoch Children's Research Institute and The Department of Paediatrics, The University of Melbourne, Australia
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Abstract

“All the vital mechanisms, however varied they may be, have only one object, that of preserving constant the conditions of life in the internal environment.”1

An essential function of the cardiopulmonary system is to generate sufficient flow of oxygenated blood around the circulation in order to maintain normal cellular metabolism. The systemic delivery of oxygen is a function of the cardiac output and the content of oxygen in the systemic arterial blood, while the extent to which metabolising tissues require this oxygen for the maintenance of their integrity and function defines the systemic consumption of oxygen. As metabolising tissues have no mechanism for storing oxygen, they depend on its continuous supply, which must at least match their changing demands. As a result, it is a fundamental requirement of survival that the systemic consumption of oxygen, at all times, is matched by appropriate levels of its delivery.

Keywords

Neurodevelopmentmass spectrometryintensive care
Type
Miscellaneous Topics
Information
Cardiology in the Young , Volume 16 , Supplement S3: Controversies and Challenges of the Atrioventricular Junctions and Other Challenges Facing Paediatric Cardiovascular Practitioners and their Patients , September 2006 , pp. 144 - 150
Copyright
© 2006 Cambridge University Press

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