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Risk factors for severe pulmonary regurgitation after repair of tetralogy of Fallot with transannular patch

Published online by Cambridge University Press:  13 November 2020

Putria Rayani Apandi Open the ORCID record for Putria Rayani Apandi [Opens in a new window] ,
Rubiana Sukardi ,
Mulyadi M. Djer ,
Piprim B. Yanuarso  and
Suprayitno Wardoyo
Putria Rayani Apandi
Affiliation:
Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia
Rubiana Sukardi*
Affiliation:
Integrated Cardiac Service, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia
Mulyadi M. Djer
Affiliation:
Departement of Child Health, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Piprim B. Yanuarso
Affiliation:
Departement of Child Health, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Suprayitno Wardoyo
Affiliation:
Departement of Cardio-Thoracic Surgery, Faculty of Medicine, Universitiy of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
*
Author for correspondence: Rubiana Sukardi, Integrated Cardiac Service, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia. E-mail: [email protected]
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Abstract

Background:

Severe pulmonary regurgitation may result in right ventricular volume overload and decreased right ventricular function. Severe pulmonary regurgitation can be predicted prior to repair of tetralogy of Fallot. The aim of this study was to determine the risk factors for severe pulmonary regurgitation in repaired tetralogy of Fallot with transannular patch.

Methods:

This was a cross-sectional study in 43 patients with repaired tetralogy of Fallot using transannular patch. This study was carried out in Dr. Cipto Mangunkusumo hospital during 2015 to 2018. Participants were followed up for routine examination using echocardiography. We used bivariate and multivariate logistic regression using STATA 12.1 to identify risk factors for severe pulmonary regurgitation in this population.

Results:

A total of 43 patients composed of 22 boys and 21 girls with repaired tetralogy of Fallot using transannular patch were enrolled in the study. Median age of participants was 6 years at admission (2.1–18.5 years) and 3.4 years (1–17 years) at repair. Median length of follow-up was 2.1(1–4.3) years. Risk factors associated with severe pulmonary regurgitation after tetralogy of Fallot repair were McGoon ratio > 1.8 (odds ratio = 6.9; 95% confidence interval = 1.6–30) and follow-up duration >1.9 years (odds ratio = 3.6; 95% confidence interval = 0.9–15.2).

Conclusion:

McGoon ratio > 1.8 and follow-up duration > 1.9 years are associated with severe pulmonary regurgitation after tetralogy of Fallot repair.

Keywords

Tetralogy of Fallottransannular patchsevere pulmonary regurgitation
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 12 , December 2020 , pp. 1917 - 1922
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Copyright
© The Author(s), 2020. Published by Cambridge University Press

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