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Prenatal diagnosis of long QT syndrome: implications for delivery room and neonatal management

Published online by Cambridge University Press:  02 May 2012

E. Anne Greene ,
Charles I. Berul  and
Mary T. Donofrio
E. Anne Greene
Affiliation:
Division of Cardiology, Children's National Medical Center, Washington, DC, United States of America Department of Pediatrics, George Washington University School of Medicine, Washington, DC, United States of America
Charles I. Berul
Affiliation:
Division of Cardiology, Children's National Medical Center, Washington, DC, United States of America Department of Pediatrics, George Washington University School of Medicine, Washington, DC, United States of America
Mary T. Donofrio*
Affiliation:
Division of Cardiology, Children's National Medical Center, Washington, DC, United States of America Department of Pediatrics, George Washington University School of Medicine, Washington, DC, United States of America
*
Correspondence to: Dr M. T. Donofrio, MD, Division of Cardiology, Children's National Medical Center, 111 Michigan Avenue, Northwest Washington, DC 20010, United States of America. Tel: 202 476 2020; Fax: 202 476 5700; E-mail: [email protected]
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Abstract

This case describes the prenatal diagnosis and integrated peripartum management of a foetus with 2:1 atrioventricular block and torsade de pointes due to congenital long QT syndrome. The unique issues related to the detection of intrauterine conduction abnormalities and ventricular arrhythmias, along with the immediate postnatal care, have been described as an interesting teaching case with successful outcome.

Keywords

Atrioventricular blocklong QT syndromefoetal arrhythmiageneticspacemaker
Type
Brief Report
Information
Cardiology in the Young , Volume 23 , Issue 1 , February 2013 , pp. 141 - 145
Copyright
Copyright © Cambridge University Press 2012

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References

1. Horigome, H, Nagashima, M, Sumitomo, N, et al. Clinical characteristics and genetic background of congenital long-QT syndrome diagnosed in fetal, neonatal, and infantile life: a nationwide questionnaire survey in Japan. Circ Arrhythm Electrophysiol 2010; 3: 10–17.Google Scholar
2. Horigome, H, Iwashita, H, Yoshinaga, M, Shimizu, W. Magnetocardiographic demonstration of torsade de pointes in a fetus with congenital long QT syndrome. J Cardiovasc Electrophysiol 2008; 19: 334–335.Google Scholar
3. Zhao, H, Strasburger, JF, Cuneo, BF, Wakai, RT. Fetal cardiac repolarization abnormalities. Am J Cardiol 2006; 98: 491–496.Google Scholar
4. Donofrio, MT, Gullquist, SD, O'Connell, NG, Redwine, FO. Fetal presentation of congenital long QT syndrome. Pediatr Cardiol 1999; 20: 441–444.Google Scholar
5. Webster, G, Berul, CI. Congenital long-QT syndromes: a clinical and genetic update from infancy through adulthood. Trends Cardiovasc Med 2009; 18: 216–224.Google Scholar