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Outcomes of closure of doubly committed subarterial ventricular septal defects in adults

Published online by Cambridge University Press:  20 April 2020

Zhaoyang Chen ,
Wanhua Chen ,
Hang Chen ,
Zhenmei Liao ,
Qiang Chen  and
Lianglong Chen Open the ORCID record for Lianglong Chen [Opens in a new window]
Zhaoyang Chen
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
Wanhua Chen
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
Hang Chen
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
Zhenmei Liao
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
Qiang Chen
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
Lianglong Chen*
Affiliation:
Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou, China
*
Author for correspondence: L. Chen, Department of Cardiology, Union Hospital, Fujian Medical University, 29 Xin-Quan Road, Fuzhou350001, China. Tel/Fax: +86-591-83308713. E-mail: [email protected]
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Abstract

Background:

Outcome data of doubly committed subarterial ventricular septal defect closure in adults are limited.

Methods:

A review was made of the inpatients >18 years of age who underwent doubly committed subarterial ventricular septal defect closure between June 2010 and June 2017.

Results:

The patients were categorised into two groups: The valve intervention group consisted of 31 patients who underwent aortic valvuloplasty, aortic valve replacement, or repair of sinus Valsalva aneurysm in addition to doubly committed subarterial ventricular septal defect closure; non-valvular intervention group comprised 58 patients who underwent only doubly committed subarterial ventricular septal defect closure. The groups did not differ by sex and age. Patients in the valve intervention group, with a larger ventricular septal defect size, were shorter and tended to be lighter. The valve intervention group had more patients with pneumonia perioperatively. No infective endocarditis and reoperation were noted during the study period. At last follow-up, 91 and 96.6% of the studied patients were free from left ventricle dilation and pulmonary hypertension. In patients without pre-operative aortic regurgitation, 12 developed new mild aortic regurgitation during the follow-up.

Conclusions:

About 34.8% of adult patients with doubly committed subarterial ventricular septal defect required concurrent intervention on aortic valve or sinus Valsalva aneurysm. The midterm results of doubly committed subarterial ventricular septal defect closure in adult patients were favourable. However, the incidence of new mild aortic regurgitation after ventricular septal defect closure was high (27.3%). Long-term follow-up of aortic regurgitation progression is needed.

Keywords

Aortic valvular regurgitationdoubly committed subarterial ventricular septal defectsurgery
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 5 , May 2020 , pp. 599 - 606
Copyright
© The Author(s) 2020. Published by Cambridge University Press

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Footnotes

*

Zhaoyang Chen, Wanhua Chen, and Hang Chen contributed equally to this paper.

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