Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-02T22:22:51.776Z Has data issue: false hasContentIssue false
  • English
  • Français

Is the function of all cardiac valves after the arterial switch operation influenced by an associated ventricular septal defect?

Published online by Cambridge University Press:  15 February 2011

J. Gabriel ,
H.-H. Scheld ,
T.D.T. Tjan ,
N. Osada  and
Thomas Krasemann
J. Gabriel
Affiliation:
Department of Thoracic and Cardiovascular Surgery, University Hospital Muenster, Albert-Schweitzer-Strasse, Muenster, Germany
H.-H. Scheld
Affiliation:
Department of Thoracic and Cardiovascular Surgery, University Hospital Muenster, Albert-Schweitzer-Strasse, Muenster, Germany
T.D.T. Tjan
Affiliation:
Department of Thoracic and Cardiovascular Surgery, University Hospital Muenster, Albert-Schweitzer-Strasse, Muenster, Germany
N. Osada
Affiliation:
Department of Medical Informatics and Biomathematics, University of Muenster, Einsteinstrasse, Muenster, Germany
Thomas Krasemann*
Affiliation:
Department of Paediatric Cardiology, Evelina Children's Hospital London, Guy's & St Thomas NHS Foundation Trust, London, United Kingdom
*
Correspondence to: T. Krasemann, Consultant Paediatric Cardiologist, Evelina Children's Hospital, Guy's & St Thomas NHS Foundation Trust, Westminster Bridge Road, London SE1 7EH, United Kingdom. Tel: 44 207 1884562; Fax: 44 207 1884556; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

A ventricular septal defect in transposition of the great arteries is frequently closely related to the cardiac valves. The valvar function after arterial switch operation of patients with transposition of the great arteries and ventricular septal defect or intact ventricular septum was compared. We analysed the function of all cardiac valves in patients who underwent the arterial switch operations pre- and post-operatively, 1 year after the procedure and on follow-up. The study included 92 patients – 64 with transposition of the great arteries/intact ventricular septum and 28 with transposition of the great arteries/ventricular septal defect. The median age at surgery was 5.5 days in transposition of the great arteries/intact ventricular septum (0–73 days) and 7.0 days in transposition of the great arteries/ventricular septal defect (4–41 days). Follow-up was 51.7 months in transposition of the great arteries/intact ventricular septum (3.3–177.3 months) and 55 months in transposition of the great arteries/ventricular septal defect (14.6–164.7 months). Neo-aortic, neo-pulmonary, and mitral valvar function did not differ. Tricuspid regurgitation was more frequent 1 year post-operatively in transposition of the great arteries/ventricular septal defect (n = 4) than in transposition of the great arteries/intact ventricular septum. The prevalence of neo-aortic regurgitation and pulmonary stenosis increased over time, especially in patients with transposition of the great arteries/intact ventricular septum. The presence of a ventricular septal defect in patients undergoing arterial switch operation for transposition of the great arteries only has a minor bearing for the development of valvar dysfunction on the longer follow-up.

Keywords

Transposition of the great arteriesarterial switchvalvar function
Type
Original Articles
Information
Cardiology in the Young , Volume 21 , Issue 4 , 12 July 2011 , pp. 383 - 391
Copyright
Copyright © Cambridge University Press 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Hoffman, JI. Incidence of congenital heart disease: I. Postnatal incidence. Pediatr Cardiol 1995; 16: 103–113.CrossRefGoogle ScholarPubMed
2.Planche, C, Lacour-Gayet, F, Serraf, A. Arterial switch. Pediatr Cardiol 1998; 19: 297–307.CrossRefGoogle ScholarPubMed
3.Jatene, AD, Fontes, VF, Paulista, PP, et al. Successful anatomic correction of transposition of great vessels: a preliminary report. Arq Bras Cardiol 1975; 28: 461–464.Google ScholarPubMed
4.Haas, F, Wotthe, M, Halger, P, Meisner, H. Long term survival and functional follow-up in patients after the arterial switch operation. Ann Thorac Surg 1999; 68: 1692–1697.CrossRefGoogle ScholarPubMed
5.von Bernuth, G. 25 years after the first arterial switch procedure: mid-term results. Thorac Cardiovasc Surg 2000; 48: 228–232.CrossRefGoogle ScholarPubMed
6.Williams, W, McCrindle, B, Ashburn, D, et al. Outcomes of 829 neonates with complete transposition of the great arteries 12–17 years after repair. Eur J Cardiothorac Surg 2003; 24: 1–10.Google Scholar
7.Hövels-Gürich, HH, Seghave, MC, Ma, Q, et al. Long-term results of cardiac and general health status in children after neonatal arterial switch operation. Ann Thorac Surg 2003; 75: 935–943.CrossRefGoogle ScholarPubMed
8.Ho Young, H, Woong-Han, K, Jae Gun, K, et al. Mit-term follow-up of neoaortic regurgitation after the arterial switch operation for transposition of the great arteries. Eur J Cardiothorac Surg 2005; 29: 162–167.Google Scholar
9.Losay, J, Touchot, A, Capderou, A, et al. Aortic valve regurgitation after arterial switch operation for transposition of the great arteries: incidence, risk factors, and outcome. J Am Coll Cardiol 2006; 47: 2057–2062.CrossRefGoogle ScholarPubMed
10.Jacob, R, Stewart, WJ. A practical approach to the quantification of valvular regurgitation. Curr Cardiol Rep 2007; 9: 105–111.CrossRefGoogle Scholar
11.Cheriex, EC, Pieters, FA, Janssen, JH, de Swart, H, Palmans-Meulemans, A. Value of exercise Doppler-echocardiography in patients with mitral stenosis. Int J Cardiol 1994; 45: 219–226.CrossRefGoogle ScholarPubMed
12.Hatle, L. Noninvasive assessment of valve lesions with Doppler ultrasound. Herz 1984; 9: 213–221.Google Scholar
13.Jatene, MB, Jatene, IB, Oliveira, P, et al. Prevalence and surgical approach of supravalvular pulmonary stenosis after Jatene operation for transposition of the great arteries. Arq Bras Cardiol 2008; 91: 17–24.Google Scholar
14.Lofland, GK, McCrindle, BW, Williams, WG, et al. Critical aortic stenosis in the neonate: a multiinstitutional study of management, outcomes, and risk factors. Congenital heart surgeons society. J Thorac Cardiovasc Surg 2001; 121: 10–27.Google Scholar
15.Yousof, AM, Shafei, MZ, Endrys, G, Khan, N, Simo, M, Cherian, G. Tricuspid stenosis and regurgitation in rheumatic heart disease: a prospective cardiac catheterization study in 525 patients. Am Heart J 1985; 110: 60–64.Google Scholar
16.Culbert, EL, Ashburn, DA, Cullen-Dean, G, et al. Quality of life of children after repair of transposition of the great arteries. Circulation 2003; 108: 857–862.CrossRefGoogle ScholarPubMed
17.Norwood, W, Dobell, A, Freed, M, Kirklin, J, Blackstone, E. Intermediate results of the arterial switch repair. A 20-institution study. J Thorac Cardiovasc Surg 1988; 96: 854–863.Google Scholar
18.Planche, C, Bruniaux, J, Lacour-Gayet, F, et al. Switch operation for transposition of the great arteries in neonates. A study of 120 patients. J Thorac Cardiovasc Surg 1988; 96: 354–363.CrossRefGoogle ScholarPubMed
19.Yacoub, MH, Radley-Smith, R, Hilton, C. Anatomical correction of complete transposition of the great arteries and ventricular septal defect in infancy. Br Med J 1976; 1: 1112–1114.Google Scholar
20.Schwartz, ML, Gauvreau, K, del Nido, P, Mayer, JE, Colan, SD. Long-term predictors of aortic root dilation and aortic regurgitation after arterial switch operation. Circulation 2004; 110 (11 Suppl. 1): II128–II132.Google Scholar
21.Marino, BS, Wernovsky, G, McElhinney, DB, et al. Neo-aortic valvar function after the arterial switch. Cardiol Young 2006; 16: 481–489.CrossRefGoogle ScholarPubMed
22.Hwang, HY, Kima, WH, Kwak, JG, et al. Mid-term follow-up of neoaortic regurgitation after the arterial switch operation for transposition of the great arteries. Eur J Cardiothoracic Surg 2006; 29: 162–167.Google Scholar
23.Gaynor, JW, O'Brien, JE Jr, Rychik, J, Sanchez, GR, DeCampli, WM, Spray, TL. Outcome following tricuspid valve detachment for ventricular septal defects closure. Eur J Cardiothorac Surg 2001; 19: 279–282.Google Scholar
24.Mullen, JC, Lemermeyer, G, Schipper, SA, Bentley, MJ. Perimembranous ventricular septal defect repair: keeping it simple. Can J Cardiol 1996; 12: 817–821.Google ScholarPubMed
25.Serraf, A, Lacour-Gayet, F, Bruniaux, J, et al. Anatomic correction of transposition of the great arteries in neonates. J Am Coll Cardiol 1993; 22: 193–200.CrossRefGoogle ScholarPubMed
26.Formigari, R, Toscano, A, Giardini, A, Di Donato, R, Picchio, FM, Pasquini, L. Prevalence and predictors of neoaortic regurgitation after arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg 2003; 126: 1753–1759.Google Scholar