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Impact of congenital heart surgery on quality of life in children and adolescents with surgically corrected Ventricular Septal Defect, Tetralogy of Fallot, and Transposition of the Great Arteries

Published online by Cambridge University Press:  09 July 2019

Line M. Holst Open the ORCID record for Line M. Holst [Opens in a new window] ,
Jonas B. Kronborg ,
Lars Idorn ,
Jesper V. Bjerre ,
Niels Vejlstrup ,
Klaus Juul  and
Hanne B. Ravn
Line M. Holst*
Affiliation:
Department of Cardiothoracic Anaesthesia, Intensive Care Unit, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Jonas B. Kronborg
Affiliation:
Department of Cardiothoracic Anaesthesia, Intensive Care Unit, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Lars Idorn
Affiliation:
Department of Paediatric Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Jesper V. Bjerre
Affiliation:
Department of Paediatric Cardiology, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, 8200 Aarhus, Denmark
Niels Vejlstrup
Affiliation:
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Klaus Juul
Affiliation:
Department of Paediatric Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Hanne B. Ravn
Affiliation:
Department of Cardiothoracic Anaesthesia, Intensive Care Unit, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
*
Author for correspondence: L. M. Holst, MD, Department of Cardiothoracic Anaesthesiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK- 2100 Copenhagen, Denmark. Tel: +4535454141; Fax: +4535452785; E-mail: line.marie.broksoe.holst.01@regionh.dk
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Abstract

Objective:

To describe the impact of CHD surgery in early childhood on quality of life in children aged 10–16 years with surgically corrected Ventricular Septal Defect, Transposition of the Great Arteries, and Tetralogy of Fallot.

Method:

A cross-sectional survey study of quality of life survey on 161 children and adolescents aged 10–16 years with surgically corrected Ventricular Septal Defect, Transposition of the Great Arteries, and Tetralogy of Fallot. The international Paediatric Quality of Life 4.0 quality of life questionnaires were applied and collected for assessment from patients and parents. The endpoints were total, physical, emotional, social, and school quality of life scores.

Results:

The quality of life total and school scores was significantly lower in children with CHD than their healthy peers. There was no significant difference in quality of life between the three CHD groups. All three CHD groups had a significantly lower total (7.7–13.2%, p<0.001) and school scores (21.1–31.6%, p<0.001) than the control group. The tetralogy of Fallot group was the only group that had significantly lower scores in the physical subscale (p<0.001) than the controls.

Conclusion:

Children and adolescents with surgically corrected CHD show losses in quality of life in total and school scores compared to healthy controls. The tetralogy of Fallot group was the only CHD group that had significantly lower physical score than the controls.

Keywords

Quality of lifeCHDVentricular Septal DefectTetralogy of FallotTransposition of the Great Arteriesquestionnaire
Type
Original Article
Information
Cardiology in the Young , Volume 29 , Issue 8 , August 2019 , pp. 1082 - 1087
Copyright
© Cambridge University Press 2019 

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