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History, diagnosis, surgery and epidemiology of pulmonary stenosis in Malta

Published online by Cambridge University Press:  19 August 2008

Victor Grech*
Affiliation:
Paediatric Department, St Lukes HospitalGuardamangia, Malta. Tel: 241251 ext. 1471 (Paediatric Department); Fax: 240176 (St Luke's Hospital)
*
Victor Grech, Paediatric Dept, St. Luke's Hospital, Guyaaradamangia, Malta. Tel 241251 Ext. 1471 (Paediatric Dept.), Fax: 240176 (St. Luke's Hospital)

Abstract

The Maltese populartion constitutes an ideal location for epidemiological and historical studies dealing with congenital hearr malformations. Pulmonary stenosis was studied retrospectively from 1943 to 1994. A sharp, significant decline in age at diagnosis was found, which predates the introduction of echocardiography. All defects are now diagnosed by echocardiography, which has resulted in an increased prevalence at birth of this lesion, patticularly of pulmonary stenosis not requiring intervention. The prevalence at birth of pulmonary stenosis from 1990 to 1994 was 1.65/1000 live births (95% CL: 1.21–2.24), with 1.11/1000 mild lesions (95% CI: 0.76–1.62) and 0.54/1000 lesions requiring intervention (95% CI: 0.31–0.92). The prevalence at birth overal was significantly higher than that reported in recent studies with similar methodologies due to the higher pickup of milder variants of pulmonary stenosis by echocardiography.Significantly more pulmonary more pulmonary stenosis was found in females than in males.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 1998

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References

1.Grech, vEmpidemiology and diagnosis of venrricular septal defect in Malta. Cardiol Young 1998; 8 (3): 329336.CrossRefGoogle Scholar
2.Mitchell, SC, Korones, SB, Berendes, HW. Congenital heart discase in 56109 births. Incidence and natural history. Circulation 1971; 43: 323332.CrossRefGoogle Scholar
3.Wilson, N, Goldberg, SJ, Dickinson, DF, Scott, O. Normal intracardiac and great arrery bolood velocity measurements by pulsed Doppler echocardiography. Br Heart J 1985; 53: 451458.CrossRefGoogle Scholar
4.Abu-harb, M, Hey, E. Death in infancey from unrecognised congenital heart disease. Arch Dis Child 1994; 71: 37.CrossRefGoogle Scholar
5.Fleiss, JLStaristical Methods for Rates and Proportions 2nd ednJohn Wiley, new york, 1981, pp.1415.Google Scholar
6.Central Office of Statistics. Demographic Review for th eMaltrese lslands for the Years 1990–1994. Malta: Central Office of sraristrics.Google Scholar
7.Samanek, M, Slavik, Z, Zborilova, B, Hrobonova, V, Voriskova, M, Skovranek, J. Prevalence, trearment and outcome of heart discase in live–born children: A prospective analysis of 91,823 live- born children. Pediatr Cardiol 1989; 10; 205211.CrossRefGoogle Scholar
8.Jackson, M, Walsh, KP, Peart, I, Arnold, REpidemiology of congenital hearr disease in Merseyside19781988. Cardiol young 1996; 6: 272280.CrossRefGoogle Scholar
9.Rashkind, WJ. Paediatric cardiology: a brief historical perspective. Pediatr Cardiol 1979; 6: 6371.CrossRefGoogle Scholar
10.Brock, RC. Pulmonary valvotomy for the relief of congenitalPulmonary stenoss. BMJ 1948; 1: 11211126.CrossRefGoogle Scholar
11.Kan, JS, White, RI Jr, Mitchell, SE, Gardner, TJ. Percutaneousballon valvoplasey: a new method of traring congenital pulmonary valve stenosis N Engl J Med 1982; 307: 540542.CrossRefGoogle ScholarPubMed
12.Fyler, DC, Buckley, CP, Hellebrand, WE, cohn, HE. Report on the New England Regional Infant Cardiac Program. Pediatrics 1980; 65: 376461.Google Scholar