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Does COVID-19 pose a threat for patients after univentricular palliation? Thrombosis of the Fontan tunnel

Part of: Covid-19

Published online by Cambridge University Press:  28 January 2022

Denisa Jičínská Open the ORCID record for Denisa Jičínská [Opens in a new window] ,
Michal Jičínský  and
Karel Koubský
Denisa Jičínská*
Affiliation:
Children’s Heart Centre, Second Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic
Michal Jičínský
Affiliation:
Children’s Heart Centre, Second Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic
Karel Koubský
Affiliation:
Children’s Heart Centre, Second Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic
*
Author for correspondence: D. Jičínská, MD, Children’s Heart Centre, Motol University Hospital, V Úvalu 84, 150 06, Prague 5, Czech Republic. Tel: +420723980115; Fax: +420224432920. E-mail: [email protected]
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Abstract

A 6-year-old boy, born with hypoplastic left heart syndrome, underwent total cavopulmonary connection and later presented in a significantly deteriorated condition. A CT scan revealed multiple thrombi in the extracardiac conduit, although the patient was maintained on an effective anticoagulant therapy. Further examination revealed anamnestic antibodies suggesting that the patient had gone through a clinically inapparent COVID-19 infection, which we conclude most likely contributed to his hypercoagulable state and led to the formation of significant thrombi impairing the patient’s haemodynamics. The patient underwent a surgical thrombectomy; there were no post-operative thrombotic complications.

Keywords

COVID-19thrombosisuniventricular circulationtotal cavopulmonary connection
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 10 , October 2022 , pp. 1698 - 1700
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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References

Connors, JM, Levy, JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood 2020; 135: 2033–2040. DOI 10.1182/BLOOD.2020006000.CrossRefGoogle ScholarPubMed
Singh, D, Jerrom, T, DClinP, RI, Saxena, R. Early thromboembolic complications after total cavopulmonary connection/Fontan operation in children: a five year single centre review. Prog Pediatr Cardiol 2021; 63: 101344. DOI 10.1016/j.ppedcard.2021.101344.CrossRefGoogle Scholar
Egbe, AC, Connolly, HM, Niaz, T, et al. Prevalence and outcome of thrombotic and embolic complications in adults after Fontan operation. Am Heart J 2017; 183: 10–17. DOI 10.1016/j.ahj.2016.09.014.CrossRefGoogle ScholarPubMed
Attard, C, Huang, J, Monagle, P, Ignjatovic, V. Pathophysiology of thrombosis and anticoagulation post Fontan surgery. Thromb Res 2018; 172: 204–213. DOI 10.1016/j.thromres.2018.04.011.CrossRefGoogle ScholarPubMed
Saleh, NY, Aboelghar, HM, Salem, SS, et al. The severity and atypical presentations of COVID-19 infection in pediatrics. BMC Pediatr 2021; 21: 1199. DOI 10.1186/s12887-021-02614-2.CrossRefGoogle Scholar
Fan, BE, Umapathi, T, Chua, K, et al. Delayed catastrophic thrombotic events in young and asymptomatic post COVID-19 patients. J Thromb Thrombolysis 2021; 51: 971–977. DOI 10.1007/s11239-020-02332-z.CrossRefGoogle Scholar
del Nonno, F, Colombo, D, Nardacci, R, Falasca, L. Fatal pulmonary arterial thrombosis in a COVID-19 patient, with asymptomatic history, occurred after swab negativization. Thromb J 2021; 19: 1807. DOI 10.1186/s12959-020-00255-6.CrossRefGoogle Scholar