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Les déclins des fonctions cognitives chez la personne âgée: Une perspective neuropsychologique

Published online by Cambridge University Press:  29 November 2010

Claude M.J. Braun  and
Robert Lalonde
Claude M.J. Braun
Affiliation:
Université du Québec à Montréal
Robert Lalonde
Affiliation:
Université du Québec à Montréal, Hôpital Hôtel-Dieu de Montréal
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Abstract

There is currently a scientific debate over the question of the existence of profiles of cognitive decline in old age which would be independent of social, health, generational factors and psychometric artefacts. This essay is a critical literature review which comes to the conclusion that evidence from neurology and neuropsychology strongly suggests the existence of such profiles. In addition, it is shown that the currently dominant neuropsychological model of aging postulates a decline of executive and mnemonic functions as a direct result of deterioration of frontal and temporal brain systems with advancing age.

Résumé

Il y a présentement une controverse scientifique sur l'existence de profile de déclins cognitifs à la sénescence qui soient indépendents de facteurs sociaux, de santé, de génération et d'artéfacts psychométriques. Ce texte est une recension critique de la littérature pertinente. Il débouche sur la conclusion que la neurologie et la neuropsychologie offrent une perspective suggérant fortement qu'il existe de tels profils de déclin. De plus, il est montré que le modèle présentement dominant en neuropsychologie de la sénescence postule l'existence de profils de déclin dans les sphères des fonctions exécutives et mnémoniques et que ces profils résultent directement d'atteintes aux systèmes frontaux et temporaux du télencéphale.

Keywords

Vieillissementneuropsychologiefonctions exécutivesfonctions mnémoniqueslobes frontauxlobes temporaux.
Type
Articles
Information
Canadian Journal on Aging / La Revue canadienne du vieillissement , Volume 9 , Issue 2 , Summer/Été 1990 , pp. 135 - 158
Copyright
Copyright © Canadian Association on Gerontology 1990

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References

Références

Abikoff, H., Alvir, J. & Hong, G. (1987). Logical memory subtest of the WMS: Age and education norms and alternate form reliability of two scoring systems. Journal of Clinical and Experimental Psychology, 9, 435–448.Google Scholar
Adams, R.D. (1980). The morphological aspects of aging in the human nervous system. In Buren, J.E. & Sloane, R.B. (Eds.), Handbook of mental health and aging, pp. 149–162. Englewood Cliffs N.J.: Prentice-Hall.Google Scholar
Alavi, A. (1989). The aging brain. Journal of Neuropsychiatry and Clinical Neu-rosciences, 1, 51–55.Google ScholarPubMed
Albert, M., Duffy, F.N., Naeser, M. (1987). Nonlinear changes in cognition with age and their neuropsychologic correlates. Canadian Journal of Psychology, 41, 141–157.Google ScholarPubMed
Albert, M.S. & Kaplan, E. (1980). Organic implications of neuropsychological deficits in the elderly. In Poon, L.W., Fozard, J.L., Cermak, L.S., Arenberg, D., & Thompson, L.W. (Eds.), New directions in memory and aging. Hillsdale NJ: Lawrence Erlbaum, pp. 403–432.Google Scholar
Albert, M. & Stafford, J. (1986). CT-neuropsychological relationships in aging and dementia. In Goldstein, G. (Ed.), Advances in Clinical Neuropsychology (Vol. 3). New York: Plenum Press.Google Scholar
Albert, M.S. & Stafford, J.L. (1988). Computed tomography studies. In Albert, M.S. & Moss, M.B. (Eds.), Geriatric neuropsychology (pp. 211–227). New York: Guil-ford.Google Scholar
Arenberg, D. (1978). Differences and changes with age in the Benton Visual Retention Test. Journal of Gerontology, 33, 534–540.CrossRefGoogle ScholarPubMed
Arenberg, D. (1982). Estimates of age changes on the Benton Visual Retention Test. Journal of Gerontology, 37, 87–90.CrossRefGoogle ScholarPubMed
Bak, J.S. & Greene, R.L. (1980). Changes in neuropsychological functioning in an aging population. Journal of Consulting and Clinical Psychology, 48, 395–399.CrossRefGoogle Scholar
Benton, A.L., Eslinger, P.J. & Damasio, A.R. (1981). Normative observations on neuropsychological test performances in old age. Journal of Clinical Neuropsychology, 3, 33–42.CrossRefGoogle ScholarPubMed
Birren, J.E., Woods, A.M., & Williams, M.V. (1980). Behavioral slowing with age: Causes, organization, and consequences. Poon, L.W. (Ed.), Aging in the 1980s. Washington DC: American Psychological Association.Google Scholar
Bondareff, W. (1977). The neural basis of aging. In Birren, J.E. & Schaie, K.W. (Eds.), Handbook of the Psychology of Aging. New York: Van Nostrand Reinhold.Google Scholar
Bornstein, R.A. & Suga, L.J. (1988). Educational level and neuropsychological performance in healthy elderly subjects. Developmental Neuropsychology, 4, 17–22.CrossRefGoogle Scholar
Borowski, J.G., Benton, H.L. & Spreen, O. (1967). Word fluency and brain damage. Neuropsychologia, 5, 135–140.CrossRefGoogle Scholar
Botwinick, J. (1967). Cognitive processes in maturity and old age. New York: Springer.CrossRefGoogle Scholar
Botwinick, J. (1977). Intellectual abilities. In Birren, J.E. & Schaie, K.W. (Eds.), Handbook of the Psychology of Aging. New York: Van Nostrand Reinhold.Google Scholar
Botwinick, J. (1985). Neuropsychology of aging. In Kandel, E. & Schwartz, . (Eds.). Principles of Neurological Science. Amsterdam: Elsevier.Google Scholar
Botwinick, J. & Birren, J.E. (1963). Mental abilities and psychomotor responses in healthy aged men. In Birren, J.E. (Ed.) Human aging: A biological and behavioral study. Bethesda: National Institute of Health.Google Scholar
Brinley, J. & Fichter, J. (1970). Performance deficits in the elderly in relation to memory load and set. Journal of Gerontology, 25, 30–35.CrossRefGoogle ScholarPubMed
Brizzee, K.R. (1975). Aging changes in relation to diseases of the nervous system. In Ordy, J.M. & Brizzee, K.R. (Eds.), Neurobiology of aging pp. 545–573, New York: Plenum Press.CrossRefGoogle Scholar
Buell, S.J. & Coleman, P.D. (1979). Dendritic growth in the aged human brain and failure of growth in senile dementia. Science 206, 854–856.CrossRefGoogle ScholarPubMed
Burger, M.G., Botwinick, F., Storandt, M. (1987). Aging, alcoholism and performance on the Luria-Nebraska Neuropsychological Battery. Journal of Gerontology, 42, 69–72.CrossRefGoogle ScholarPubMed
Cattell, R.B. (1963). Theory of fluid and crystallized intelligence: A critical experiment. Journal of Educational psychology, 54, 1–22.CrossRefGoogle Scholar
Cerella, J., Poon, L.W. & Williams, D.M. (1980). Age and the complexity hypothesis. In Poon, L.W. (Ed.), Aging in the 1980s. Washington, DC: APA.Google Scholar
Chapman, L.J., & Chapman, J.P. (1973). Problems in the measurement of cognitive deficit. Psychological Bulletin, 79, 380–383.CrossRefGoogle ScholarPubMed
Chapman, J.P. & Chapman, L.J. (1983). Reliability and the discrimination of normal and pathological groups. The Journal of Nervous and Mental Disease, 171, 658–661.CrossRefGoogle ScholarPubMed
Correll, R.E., Rokosz, S. & Blanchard, B. (1966). Some correlations of WAIS performance in the elderly. Journal of Gerontology, 21, 544–549.CrossRefGoogle ScholarPubMed
Corsellis, J.A.N. (1969). The pathology of dementia. British Journal of Hospital Medicine, 695–703.Google Scholar
Corsi, P.M. (1972). Human memory and the medial temporal region of the brain. Ph.D. Thesis, McGill University.Google Scholar
Craik, F.I.M. (1977). Age differences in human memory. Birren, J.E. & Schaie, K.W. (Eds.), Handbook of the Psychology of Aging. New York: Van Nostrand Rein-hold.Google Scholar
Daigneault, S., Braun, C, Mergler, D., Proulx, R. & Gilbert, B. (1987). Canonical and factorial structures of a frontal battery of tests. Journal of Clinical and Experimental Neuropsychology, 10, 58.Google Scholar
Davies, A.D.M. (1968). The influence of age on Trail Making Test Performance. Journal of Clinical Psychology, 24, 96–98.3.0.CO;2-U>CrossRefGoogle ScholarPubMed
Delbecq-Derouesné, J. & Beauvois, M.F. (1989). Memory processes and aging: a defect of automatic rather than controlled processes? Archives of Gerontology and Geriatrics, Suppl. 1, 121–150.Google ScholarPubMed
Duffy, F.H., Albert, M.S., McNaulty, G. & Garvey, A.J. (1984). Age-related differences in brain electrical activity of healthy subjects. Annals of Neurology, 16, 430–438.CrossRefGoogle ScholarPubMed
Erkinjuntti, T., Laaksonen, R., Sulkava, R., Syrjalainen, R. & Palo, J. (1986). Neuropsychological differentiation between normal aging, Alzheimer&s disease and vascular dementia. Ada Neurologica Scandinavia, 74, 393–403.CrossRefGoogle ScholarPubMed
Eslinger, D.J. & Benton, A.L. (1983). Visuoperceptual performances in aging and dementia: Clinical and theoretical implications. Journal of Clinical Neuropsychology, 5, 213–220.CrossRefGoogle ScholarPubMed
Fromm-Auch, D., Yeudall, L.T. (1983). Normative data for the Halstead-Reitan neuropsychological. Journal of Clinical Neuropsychology, 5, 221–238.CrossRefGoogle ScholarPubMed
Furry, C.A. & Baltes, P.B. (1973). The effect of age diffferences in ability-extraneous performance variables on the assessment of intelligence in children, adults and the elderly. Journal of Gerontology, 28, 73–80.CrossRefGoogle Scholar
George, A.E., DeLeon, M.J., & Kalnin, A. (1986). Leukoencephalopathy in normal and pathologic aging-II: MRI of brain lucencies. American Journal of Neu-roradiology, 7, 567–570.Google Scholar
Gérard, R.W. (1959). Aging and organization. In Birren, J.E. (Ed.), Handbook of aging and the individual, pp. 264–275. Chicago, University of Chicago Press.Google Scholar
Gérard, G. & Weisberg, L.A. (1986). MRI periventricular lesions in adults. Neurology, 36, 998–1001.CrossRefGoogle ScholarPubMed
Goldberg, E. (1986). Varieties of perseveration: A comparison of two taxonomies. Journal of Clinical and Experimental Neuropsychology, 8, 710–726.CrossRefGoogle ScholarPubMed
Goldstein, G. & Shelby, C.H. (1975). Similarities and differences between psychological deficit in aging and brain damage. Journal of Gerontology, 30, 448–455.CrossRefGoogle ScholarPubMed
Greenfield, C.I., Margolis, R.B. & Erker, G.J. (1985). Application of the Trail Making Test in differentiating neuropsychological impairment of elderly persons. Perceptual and Motor Skills, 61, 1283–1289.Google Scholar
Gur, R.C., Gur, R.E., Obirst, W.D., Skolnick, B.E., & Reiwich, M. (1987). Age and regional cerebral blod flow at rest and during cognitive activity. Archives of General Psychiatry, 44, 617–621.CrossRefGoogle Scholar
Hachinski, V.C., Potter, P. & Merskwy, H. (1987). Leuko-aroiosis. Archives of Neurology, 44, 21–23.CrossRefGoogle Scholar
Halicka, I. (1978). Cognitive functionning in late adulthood. Washington, DC: American Psychological Association.Google Scholar
Hallenbeck, C.E. (1964). Evidence for a multiple process view of mental deterioration. Journal of Gerontology, 19, 357–363.CrossRefGoogle ScholarPubMed
Hang, H., Barmwater, U., Eggers, R., Fisher, D., Kuhl, S., & Sass, N.L. (1983). Anatomical changes in the aging brain: morphometric analysis of the human prosencephalon. In Cervos-Navarro, J. & Scharkander, H.I. (Eds.), Neurophar-macology (Aging Vol. 20) 1–12, New York: Raven Press.Google Scholar
Hartley, J.T., Harker, J.O., Walsh, D.A. (1980). Contemporary issues and new directions in adult development of learning and memory. In. Poon, L.W. (Ed.), Aging in the 1980s. Washington DC: APA.Google Scholar
Heaton, R.K. (1981). Wisconsin Card Sorting Test. Odessa: Psychological Assessment Resources Inc.Google Scholar
Heaton, R.K., Grant, I. & Matthews, C. (1986). Differences in neuropsychological test performance associated with age, education and sex. In Grant, I. & Adams, K.M. (Eds.), Neuropsychological assessment of neuro-psychiatric disorders, pp. 100–120, New York, Oxford University Press.Google Scholar
Hochanadel, G. & Kaplan, E. (1984). Neuropsychology of normal aging. In Albert, M. (Ed.), Clinical neurology of aging. New York: Oxford University Press, pp. 231–244.Google Scholar
Horwitz, B. (1987). Brain metabolism and blood flow during aging. Electroencephalography and Clinical Neurophysiology (Suppl.) 39, 396–402.Google ScholarPubMed
Jacob, L. & Grossman, L. (1980). Three primitive reflexes in normal adults. Neurology, 30, 184–192.CrossRefGoogle Scholar
Kahn, R.L., Goldforb, R.I., Pollack, M. & Gerber, I.E. (1962). The relationship of mental and physical status in institutionalized elderly persons. American Journal of Psychiatry, 117, 120–124.CrossRefGoogle Scholar
Kemper, T. (1984). Neuroanatomical and neuropathological changes in normal aging and in dementia. In Albert, M.L. (Ed.), Clinical neurology of aging (pp. 9–52). New York: Oxford University Press.Google Scholar
Kennedy, K.J. (1981). Age effects on Trail Making Test performance. Perceptual and Motor Skills, 52, 671–675.CrossRefGoogle ScholarPubMed
Klisz, D. (1978). Neuropsychological evaluation of older persons. In Storandt, M., Siegler, E.C. & Elias, M.F. (Eds.) The clinical psychology of aging, pp. 71–96. New York: Plenum.CrossRefGoogle Scholar
Kolb, B. & Wishaw, I.Q. (1985). Fundamentals of human neuropsychology. New York: W.H. Freeman.Google Scholar
Lassen, N.A. & Ingvor, D.H. (1980). Blood flow studies in the aging normal brain and in senile dementia. In Amaducci, L., Davison, A.N. & Antuono, P.A.. (Eds.) Aging of the brain and dementia. Vol. 13, pp. 91–98. New York: Raven.Google Scholar
Lezak, M.D. (1983). Neuropsychological Assessment, 2nd ed.New York: Oxford University Press.Google Scholar
L'Hermitte, F. & Signoret, J.L. (1972). Analyse neuropsychologique et différentiation des syndromes amnésiques. Revue de Neurologie, 126, 161–178.Google Scholar
Lindsey, B.A. & Coppinger, N.W. (1969). Age-related deficits in simple capabilities and their consequences for Trail-Making performance. Journal of Clinical Psychology, 25, 156–159.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Loveless, N.E. & Sanford, A.J. (1974). Effects of age on the contingent negative variation and preparatory set in a reaction-time task. Journal of Gerontology, 29, 52–63.CrossRefGoogle Scholar
Luria, A.R. (1976). The neuropsychology of memory. Washington, DC: V.H. Winston & Sons.Google Scholar
Luria, A.R. (1977). The working brain. New York. Basic Books.Google Scholar
Luria, A.R. (1980). Cortical functions in man. (2nd ed.) New York: Basic Books.CrossRefGoogle Scholar
Maclnnes, W.D., Gillen, R.W., Golden, C.J., Graber, B., Cole, J.K., Uhl, H.S.M. & Greenhouse, A.H. (1983). Aging and performance on the LNNB. International Journal of Neuroscience 19, 179–190.Google Scholar
Maclnnes, W.D., Golden, C.J., Gillen, R.W., Sawicki, R.F, Quaife, M, Uhl, H.S.M. & Greenhouse, A.J. (1984). Aging, regional cerebral blood flow & neuropsychological functionning. Journal of the American Geriatrics Society, 32, 712–718.CrossRefGoogle Scholar
Mazzucchi, A., Mutti, A., Poletti, A., Ravanetti, C, Novoicin, A., Parma, M. (1986). Neuropsychological deficits in arterial hypertension. Ada Neurologica Scandinavia, 73, 619–627.CrossRefGoogle ScholarPubMed
McGeer, E. & McGeer, P.L. (1976). Neurotransmitter metabolism in the aging brain. In Terry, R.D. and Gershon, S. (Eds.) Aging Vol. 3. Neurobiology of Aging. New York. Raven Press.Google Scholar
Michalewski, H.J., Thompson, L.W., Smith, D.B.D., Patterson, J.V., Bowman, T.E., Litzelman, D. & Brent, G. (1980). Age differences in the contingent negative variation (CNV). Reduced frontal activity in the elderly. Journal of Gerontology, 35, 542–549.CrossRefGoogle ScholarPubMed
Miller, E. (1977). Abnormal aging. London: Wiley.Google Scholar
Milner, B. (1971). Interhemispheric differences in the localization of psychological processes in man. British Medical Bulletin, 27, 272–277.CrossRefGoogle ScholarPubMed
Milner, B. (1972). Some cognitive effects of frontal-lobe lesions in man. Philosophical Transcripts of the Royal Society of London, 298, 211–226.Google Scholar
Milner, B. & Petrides, M. (1984). Behavioral effects of frontal-lobe lesions in man. Trends in Neurosciences, 7, 403–407.CrossRefGoogle Scholar
Mints, A.Y., Litvinenko, A.A., Bachinskaya, N.Y. (1988). Cerebral circulation and certain parameters of the functional state of the brain in the process of aging. Soviet Neurology and Psychiatry, 20, 3–11.Google Scholar
Mittenberg, W., Seidenberg, M., O'Leary, D.S. & DiGiulio, D.V. (1989). Changes associated with normal aging. Journal of Clinical and Experimental Neuropsychology, 11, 918–933.CrossRefGoogle ScholarPubMed
Morimatsy, M., Hirai, S., Muzamatsu, A., & Yoshikawa, M. (1975). Senile degenerative brain lesions and dementia. Journal of the American Geriatric Society, 23, 390–406.CrossRefGoogle Scholar
Moscovitch, M. (1982). Multiple dissociations of function in amnesia. In Cermak, L.S. (Ed.), Human memory and amnesia. Hillsdale N.J.: Erlbaum.Google Scholar
Moscovitch, M. (1982). A neuropsychological approach to perception and memory in normal and pathological aging. In Craik, F.I.M. & Trehub, S. (Eds.) Advances in the study of communication and affect. (Vol. 8) pp. 55–78New York: Plenum.Google Scholar
Nakameira, M., Fukui, Y., Kadobauyashi, I. & Katoh, N. (1979). A comparison of CNV in young and old subjects: its relation to memory and personality. Electroencephalography and Clinical Neurophysiology, 46, 1337–1344.Google Scholar
Obrist, W.D. & Busse, E.W. (1960). Temporal lobe EEG abnormalities in normal senescence. Electroencephalography and Clinical Neurophysiology, 12, 244–253.Google Scholar
Peak, D.T. (1968). Changes in short term memory in a group of aging community residents. Journal of Gerontology, 23, 9–16.CrossRefGoogle Scholar
Petrides, M. & Milner, B. (1982). Deficits on subject ordered tasks after frontal and temporal lobe lesions in man. Neuropsychologia, 20, 249–262.CrossRefGoogle ScholarPubMed
Pfefferbaum, A., Ford, J.M., Roth, W.T., Hopkins, W.K. & Kopell, B.S. (1979). Event-related potential changes in healthy aged females. Electroencephalography and Clinical Neurophysiology, 46, 81–86.CrossRefGoogle ScholarPubMed
Pfefferbaum, A., Ford, J., Roth, W. & Kopell, B. (1980). Age-related changes in auditory event-related potentials. Electroencephalography and Clinical Neurophysiology, 49, 266–276.CrossRefGoogle ScholarPubMed
Powell, A.H., Eisdorfer, C., Bogdanoff, M.D. (1964). Physiologic response patterns observed in a learning task. Archives of General Psychiatry, 10, 192–195.CrossRefGoogle Scholar
Price, L.J., Fein, G., Feinberg, I. (1980). Neuropsychological assessment of cognitive function in the elderly. In Poon, L.W. (Ed.), Aging in the 1980s. Washington, DC. APA.Google Scholar
Rabbitt, P.M.A., Clancy, M.G. & Vyas, S.M. (1969). Proceedings of XVII International Congress of Gerontology, Washington.Google Scholar
Rockstein, M. (1974). The genetic basis of longevity. In Rockstein, M., Sussman, M.L., & Chesky, J. (Eds.), Theoretical aspects of aging pp. 1–10, New York: Academic Press.Google Scholar
Roman, G.C. (1987). Senile dementia of the Binswanger type. A vascular form of dementia in the elderly. Journal of the American Medical Association. 258, 1782–1788.CrossRefGoogle ScholarPubMed
Rudinger, G. (1976). Correlates of changes in cognitive functioning. Thomas, H. (Ed.), Patterns of Aging pp. 20–35, Basel: Karger.Google Scholar
Schaie, K.W. & Baltes, P.B. (1977). Some faith helps to see the forest: a final comment on the Horn and Donaldson myth of the Baltes-Schaie position on adult intelligence. American Psychologist, 32, 1118–1120.CrossRefGoogle Scholar
Schaie, K.W. & Labouvie-Viel, G. (1974). Generational versus ontogenetic components of change in adult cognitive behavior: A fourteen-year cross-sequential study. Developmental Psychology, 10, 305–320.CrossRefGoogle Scholar
Schaie, K.W. & Schaie, J.P. (1977). Clinical assessment and aging. In Birren, J.P. & Schaie, K.W. (Eds.) Handbook of the psychology of aging, pp. 692–723. New York: Van Nostrand.Google Scholar
Schaie, K.W. & Strothen, C.R. (1968). A cross-sequential study of age changes in cognitive behavior. Psychological Bulletin, 70, 671–680.CrossRefGoogle ScholarPubMed
Scheibel, M.E. & Scheibel, A.B. (1975). Structural changes in the aging brain. In Brody, H., Harmon, D. & Ordy, J.M., (Eds.), Aging Vol. 1. New York: Raven Press.Google Scholar
Schludermann, S.M., Menyman, P.W. & Brown, B.W. (1983). Halstead's studies in the neuropsychology of aging. Archives of Gerontological Geriatrics, 2, 50–172.Google ScholarPubMed
Shaw, T.G., Mortel, K.F., Meyer, J.S., Rogers, R.L., Hardenberg, J., & Cutaia, M.H. (1984). Cerebral blood flow changes in benign aging and cerebrovascular disease. Neurology, 34, 855–862.CrossRefGoogle ScholarPubMed
Shelton, M.D., Parsons, O.A. & Leber, W.R. (1982). Verbal and visuospatial performance and aging: a neuropsychological approach. Journal of Gerontology, 37, 1336–341.CrossRefGoogle ScholarPubMed
Spieth, W. (1965). Slowness of task performance and cardiovascular diseases. In Welford, A.T. & Birren, J.E. (Eds.) Behavior aging and the nervous system pp. 366–400, Springfield Ill: Thomas.Google Scholar
Spitzform, M. (1985). Normative data in the elderly on the LNNB. Clinical Neuropsychology, 4, 103–105.Google Scholar
Squire, L.R. (1982). Comparisons between forms of amnesia: Some deficits are unique to Korsakoff s syndrome. Journal of Experimental Psychology: Learning Memory and Cognition, 8, 560–571.Google ScholarPubMed
Squire, L.R. (1987). Memory and brain. New York: Oxford University Press.Google Scholar
Squire, L. & Butters, N. (1984). Neuropsychology of memory. New York: Guilford Press.CrossRefGoogle Scholar
Stanton, B.A., CD., Jenkins, Savageau, J.A. & Zyzanski, S.J. (1984). Age and educational differences on the Trail Making Test and Wechsler memory scales. Perceptual and Motor Skills, 58, 311–318.CrossRefGoogle Scholar
Steingart, A., Hachinski, V.C., Lau, C, Fox, A., Dioz, F., Cape, R., Lee, D., Inzitari, D. & Merkey, H. (1987). Cognitive and neurologic findings in subjects with diffuse white matter lucenies on CT scan. Archives of Neurology, 44, 32–35.CrossRefGoogle Scholar
Strehler, B.L. (1975). Implications of aging research for society. Federal Proceedings, 34, 5–8.Google ScholarPubMed
Stuss, D.T., Benson, D.F., Kaplan, E.F., Weis, W.S., Delia Malva, C. (1981). Leucotomized and non-leucotomized schizophrenics comparison on tests of attention. Biological Psychiatry, 16, 1085–1100.Google Scholar
Stuss, D.T., Kaplan, E.F., Benson, D.F., Weir, W.S., Chiulli, S. & Sarrazin, F.F. (1982). Evidence for the involvement of orbitofrontal cortex in memory functions: an interference effect. Journal of Comparative and Physiological Psychology, 96, 913–925.CrossRefGoogle ScholarPubMed
Survillo, W.W. (1966). The relation of autonomic activity to age differences in vigilance. Journal of Gerontology, 21, 257–260.CrossRefGoogle Scholar
Taylor, M.A., Sierles, F.S. & Abrams, R. (1985). Primitive reflexes in psychiatry. General Hospital Psychiatry. New York: The Free Press.Google Scholar
Tecce, J.J. (1972). Contingent negative variation (CNV) and psychological processes in man. Psychological Bulletin, 77, 73–108.CrossRefGoogle ScholarPubMed
Tecce, J.J. (1978). Contingent negative variation and attention functions in the aged. In Calaway, E., Tueting, P. & Koslow, S.H. (Eds.) Event-related potentials in man. New York: Academic Press.Google Scholar
Terry, R.D. & Wisniewski, H.M. (1975). Structural and chemical changes of the aged human brain. In Gershon, S. & Raskin, A. (Eds.), Aging Vol. 2. New York: Raven Press.Google Scholar
Thaler, M. (1950). Relationships among Wechsler, Weigl, Rorschach, EEG findings and abstract-concrete behavior in a group of normal aged subjects. Journal of Gerontology, 11, 404–409.CrossRefGoogle Scholar
Tomlinson, B.E., Blessed, G. & Roth, M. (1970). Observations on the brains of demented old people. Journal of Neurological Sciences. 11, 205–242.CrossRefGoogle ScholarPubMed
Tomlinson, B.E. & Kitchener, D. (1972). Granulovacuolar degeneration of hippocampal pyramidal cells. Journal of Pathology, 106, 165–185.CrossRefGoogle ScholarPubMed
Troyer, L.W., Eisdorfer, C, Wilkie, F., & Bogdanoff, M.D.; (1966). Free fatty acid responses in the aged individual during performance of learning tasks. Journal of Gerontology, 21, 45–51.CrossRefGoogle ScholarPubMed
Vega, A., & Parsons, O.A. (1967). Cross-validation of the Halstead-Reitan tests for brain damage. Journal of Consulting and Clinical Psychology, 31, 619–623.CrossRefGoogle ScholarPubMed
Veroff, A.E. (1980). The neuropsychology of aging: qualitative analysis of visual reproductions. Psychological Research, 41, 1259–1268.CrossRefGoogle ScholarPubMed
Veroff, A.E., Kaplan, E., Albert, M.L., Wolf, P., Rosen, W., Dawber, T.R., Kannel, W.B. & McNamara, P.M. (1979). Aging and dementia in the Framingham Hearth Study populations. Paper presented at the meeting of the International Neuropsychological Society, New York.Google Scholar
Walter, W.G. (1968). The contingent negative variation: An electro-cortical sign of sensori-motor reflex association in man. In Asratyan, E.A. (Ed.), Progress in brain research Vol. 22: Brain reflexes. Amsterdam: Elsevier.Google Scholar
Warren, L.R., Buttler, R.W., Katholi, C.R. & Halsey, J.H. (1985). Age differences in cerebral blood flow during rest and during mental activation. Journal of Gerontology, 40, 53–59.CrossRefGoogle ScholarPubMed
Warrington, E.K. (1982). The double dissociation of short and long term memory deficits. In Cermak, L.S. (Ed.), Human Memory and amnesia. Hilsdale, NJ: Erlbaum.Google ScholarPubMed
Wechsler, D. (1945). A standardized memory scale for clinical use. Journal of Psychology, 19, 87–95.CrossRefGoogle Scholar
Wechsler, D. (1958). The measurement and appraisal of adult intelligence. Baltimore: Williams & Wilkins.Google Scholar
Whelihan, W.M. & Lesher, E.L. (1985). Neuropsychological changes in frontal functions in aging. Developmental Neuropsychology, 1, 371–380.CrossRefGoogle Scholar
Willis, L., Yeo, R.A., Thomas, P. & Garry, P.J. (1988). Differential declines in cognitive function in aging: the possible role of health status. Developmental Neuropsychology, 44, 23–28.CrossRefGoogle Scholar
Wilson, D.L. (1974). The programme theory of aging. In Rockstein, M., Sussman, M.L. & Chesky, J. (Eds.), Theoritical aspects of aging pp. 11–21, New York: Academic Press.CrossRefGoogle Scholar
Yeudall, L.T., Fromm, D., Reddon, J.R., Stetanyk, W.O. (1986). Normative data stratified by age and sex for 12 neuropsychological tests. Journal of Clinical Psychology, 42, 918–946.3.0.CO;2-Y>CrossRefGoogle Scholar
Zelinski, E.M., Walsh, D.A., & Thompson, L.W. (1978). Orienting task effects on EDR and free recall in three age groups. Journal of Gerontology, 33, 239–245.CrossRefGoogle ScholarPubMed
Zimmerman, R.D., Fleming, C.A., Lee, B., Saint-Louis, L.A. & Deck, M. (1986). Periventricular hyperintensity as seen by magnetic resonance: prevalence and significance. American Journal of Radiology, 146, 433–150.Google Scholar