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Geochemical Risk Factors for Mental Functioning, Based on the Ontario Longitudinal Study of Aging (LSA) III. The Effects of Different Aluminum-containing Compounds

Published online by Cambridge University Press:  29 November 2010

W. F. Forbes  and
N. Agwani
W. F. Forbes
Affiliation:
University of Waterloo*
N. Agwani
Affiliation:
University of Waterloo*
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Abstract

Previous work on the association between total aluminum (Al) concentrations and a measure of cognitive impairment is extended by considering the associations between this measure of cognitive impairment, not only with total Al, but also with turbidity and DOC both of which also contain Al. The multivariate, but not bivariate, analyses show that the odds of showing indications of mental impairment increase with turbidity but decrease with DOC, and this effect is most pronounced at a medium pH. It is suggested that the two variables considered could account for some of the unexplained features of the association between Al concentrations and measures of cognitive impairment. The other associations, namely those with F, pH, source of drinking water (ground or surface) remain similar to those reported previously in this series of papers.

Résumé

On pousse plus loin les travaux antérieurs sur l'association entre les concentrations totales d'aluminium (Al) et une mesure de la déficience cognitive en tentant de relier cette mesure non seulement aux concentrations totales d'aluminium mais aussi à la turbidité et au carbone organique dissous, deux facteurs qui contribuent vraisemblablement de manière appréciable à la concentration d'aluminium. L'analyse multifactorielle, mais non l'analyse à deux variables, donne à entendre que la déficience cognitive augmente avec la turbidité et diminue avec la concentration de carbone organique dissous, et que cet effet est le plus marqué lorsque le pH est moyen. Les résultats obtenus pour les autres associations, notamment avec le fluor, le pH et la source d'eau potable (souterraine ou superficielle), sont comparables à ceux qui ont été signalés antérieurement.

Keywords

AluminumSpeciationpHCognitive Impairment.AluminiumpHdéficit cognitif.
Type
Articles
Information
Canadian Journal on Aging / La Revue canadienne du vieillissement , Volume 13 , Issue 4 , Winter/hiver 1994 , pp. 488 - 498
Copyright
Copyright © Canadian Association on Gerontology 1994

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