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Association of Alcohol Consumption with Cognition and Functionality in Older Adults Aged 75+ Years: The Pietà Study

Published online by Cambridge University Press:  12 March 2024

Mariana Alves de Almeida Open the ORCID record for Mariana Alves de Almeida [Opens in a new window] ,
Maira Tonidandel Barbosa ,
Elisa de Paula França Resende ,
Viviane Amaral Carvalho ,
Ana Paula Borges Santos ,
João Carlos Barbosa Machado ,
Vivian Proença Lara ,
Karina Braga Gomes ,
Thais Helena Machado  and
Paulo Caramelli
Mariana Alves de Almeida
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Maira Tonidandel Barbosa
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil
Elisa de Paula França Resende
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil Hospital das Clínicas da Universidade Federal de Minas Gerais/EBSERH, Belo Horizonte, MG, Brazil
Viviane Amaral Carvalho
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Ana Paula Borges Santos
Affiliation:
Hospital das Clínicas da Universidade Federal de Minas Gerais/EBSERH, Belo Horizonte, MG, Brazil
João Carlos Barbosa Machado
Affiliation:
Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil
Vivian Proença Lara
Affiliation:
Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Karina Braga Gomes
Affiliation:
Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Thais Helena Machado
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil Departamento de Fonoaudiologia, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Paulo Caramelli*
Affiliation:
Behavioral and Cognitive Neurology Research Group, Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
*
Corresponding author: Paulo Caramelli, MD, PhD, Departamento de Clínica Médica, Faculdade de Medicina da UFMG, Av. Prof. Alfredo Balena, 190 – sala 246, Belo Horizonte, MG, 30130-100, Brazil. Tel: +55 (31) 3409-9746 ([email protected]).
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Abstract

The relationship between alcohol consumption and cognition is still controversial. This is a cross-sectional population-based study conducted in Caeté (MG), Brazil, where 602 individuals aged 75+ years, 63.6% female, and with a mean education of 2.68 years, were submitted to thorough clinical assessments and categorized according to the number of alcoholic beverages consumed weekly. The prevalence rates of previous and current alcohol consumption were 34.6% and 12.3%, respectively. No association emerged between cognitive diagnoses and current/previous alcohol consumption categories. Considering current alcohol intake as a dichotomous variable, the absence of alcohol consumption was associated with dementia (OR = 2.34; 95%CI: 1.39–3.90) and worse functionality (p = 0.001). Previous consumption of cachaça (sugar cane liquor) increased the risk of dementia by 2.52 (95%CI: 1.25–5.04). The association between the consumption of cachaça and dementia diagnosis has not been described before.

Résumé

Résumé

La rélation entre l’alcool et la cognition est encore controversée. II s’agit d’une étude transversale populationnelle menée au Caeté (MG), Brésil où 602 personnes âgées de 75+ ans, 63.6% femmes et avec une éducation moyenne de 2.68 ans, ont été soumises à des évaluations cliniques détaillées et classées face au nombre de boissons alcooliques consommées par semaine. Les prévalences de consommation d’alcool antérieure/actuelle étaient de 34.6% et 12.3%, respectivement. Aucune association n’a émergé entre les diagnostics cognitifs et la consommation d’alcool. L’absence de consommation actuelle d’alcool était associée à la démence (OR = 2.34; IC à 95%: 1.39–3.90) et à une pire fonctionnalité (p = 0.001). La consommation antérieure de cachaça (liqueur de canne à sucre) a augmenté la chance du diagnostic de démence de 2.52 (IC à 95%: 1.25–5.04). Cette association entre la consommation de cachaça et démence n’a pas été registré auparavant.

Keywords

alcoholalcoholic beveragedementiacognitionagingAlcoolboisson alcooliséedémencecognitionvieillissement
Type
Article
Information
Canadian Journal on Aging / La Revue canadienne du vieillissement , Volume 43 , Issue 4 , December 2024 , pp. 518 - 528
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Copyright
© Canadian Association on Gerontology 2024

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