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Vein of Galen Malformation with Cerebral Calcification: A Reversible Cause of Neurodegenerative Disease

Published online by Cambridge University Press:  18 September 2015

Stephen J. Phillips ,
Joseph M. Dooley  and
Peter R. Camfield
Stephen J. Phillips
Affiliation:
Departments of Medicine and Pediatrics, Dalhousie University, Halifax, Nova Scotia
Joseph M. Dooley*
Affiliation:
Departments of Medicine and Pediatrics, Dalhousie University, Halifax, Nova Scotia
Peter R. Camfield
Affiliation:
Departments of Medicine and Pediatrics, Dalhousie University, Halifax, Nova Scotia
*
Izaak Walton Killam Hospital for Children, P.O. Box 3070, Halifax, Nova Scotia, Canada B3J 3G9
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Abstract:

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This paper reports two children who had mental retardation as the predominant manifestation of vein of Galen malformations. C.T. scans demonstrated extensive intracerebral calcification. Surgery reversed the progressive downhill course in one patient and may have arrested further deterioration in the other. The pathophysiological mechanisms underlying the clinical and radiographic features are discussed.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue 2 , May 1986 , pp. 103 - 106
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

References

REFERENCES

1.Padget, DH. The cranial venous system in man in reference to development adult configuration, and relation to the arteries. Am J Anat 1956:98: 307–355.CrossRefGoogle Scholar
2.Gomez, MR, Whitten, CF, Nolke, Aet al. Aneurysmal malformation of the great vein of Galen causing heart failure in early infancy. Report of five cases. Pediatrics 1963: 31: 400–441.CrossRefGoogle Scholar
3.Stern, L, Ramos, AD, Wiglesworth, FW. Congestive heart failure secondary to cerebral arteriovenous aneurysm in the newborn infant. Am J Dis Child 1968: 155: 581–587.Google Scholar
4.Moodie, DS. Sterba, R. Rothner, ADet al. Great vein of Galen malformations in infancy. Cleve Clin Q 1983; 50: 295–301.CrossRefGoogle ScholarPubMed
5.Gold, AP, Ransohoff, J, Carter, S. Vein of Galen malformation. Acta Neurol (Scand) 1964; 40 (Suppl 11).Google ScholarPubMed
6.Amacher, AL, Shillito, J. The syndromes and surgical treatment of aneurysms of the great vein of Galen. J. Neurosurg 1973; 39: 89–98.CrossRefGoogle ScholarPubMed
7.Fernandez, RE. Kishore, PR, Wilson, Met al. Unusual manifestations of vein of Galen aneurysm AJNR 1982; 3: 440–441.Google Scholar
8.MacPherson, P, Teadale, GM, Lindsay, KW. Computed tomography in diagnosis and management of aneurysm of the vein of Galen. J Neurol Neurosurg Psychiatr 1979: 42: 786–789.CrossRefGoogle ScholarPubMed
9.Spallone, A. Computed tomography in aneurysms of the vein of Galen. J Comput Assist Tom 1979; 3(6): 799–782.Google ScholarPubMed
10.Iannucci, AM, Buonanno, F, Rizzuto, Net al. Arteriovenous aneurysm of the vein of Galen: a clinical, angiographic and neuro-pathological study. J Neurol Sci 1979: 40: 29–37.CrossRefGoogle Scholar
11.Martelli, A. Scotti, G, Harwood-Nash, DCet al. Aneurysms of the vein of Galen in children: CT and angiographic correlation. Neuroradiology 1980:20: 123–133.CrossRefGoogle Scholar
12.Rao, KC. Chiantella, NM, Arora, Setal. Intracranial venous aneurysms: vein of Galen and other similar vascular anomalies. CT 1983; 7: 345–350.Google ScholarPubMed
13.Diebler, C, Dulac, O, Renier, Det al. Aneurysms of the vein of Galen in infants aged 2-15 months. Diagnosis and natural evolution. Neuroradiology. 1981:21: 185–197.CrossRefGoogle Scholar
14.Bayley, N. Bayley scales of infant development. California: The Pyschological Corp. 1969.Google Scholar
15.Rosman, NP, Shands, KN. Hydrocephalus caused by increased intracranial venous pressure: a clinicopathological study. Ann Neurol 1978; 3: 445–450.CrossRefGoogle ScholarPubMed
16.Norman, MC, Becker, LE. Cerebral damage in neonates resulting from arteriovenous malformations of the vein of Galen. J Neurol Neurosurg Psychiatr 1974; 37: 252–258.CrossRefGoogle ScholarPubMed
17.Perez Fontan, J, Herrera, M, Fina, A, Peguero, G. Periventricular calcifications in a newborn associated with aneurysm of the great vein of Galen. Pediatr Radiol 1982; 12: 249–251.CrossRefGoogle Scholar
18.Brunelle, FO, Harwood-Nash, DC, Fitz, CR. Chuang, SH. Intracranial vascular malformations in children: computed tomographic and angiographic evaluation. Radiology 1983: 149: 455–461.CrossRefGoogle ScholarPubMed