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Responses in Skin Microcirculation to Vestibular Stimulation Before and During Motion Sickness

Published online by Cambridge University Press:  18 September 2015

Ognyan I. Kolev ,
Claes Möller ,
Gert Nilsson  and
Lita Tibbling
Ognyan I. Kolev*
Affiliation:
visiting Research Scientist, at present in, Universities Space Research Association, Division of Space Life Sciences, Houston, Texas, USA.
Claes Möller
Affiliation:
Departments of Otorhinolaryngology, University Hospital, Linköping, Sweden
Gert Nilsson
Affiliation:
Biomedical Engineering, University Hospital, Linköping, Sweden
Lita Tibbling
Affiliation:
Departments of Otorhinolaryngology, University Hospital, Linköping, Sweden
*
Universities Space Research Association, Division of Space Life Sciences, 3600 Bay Area Boulevard, Houston, Texas, USA 77058
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Abstract:

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Background:

Observation of physiological changes during motion sickness is required to quantify the degree of sickness. The review of the literature does not show unifying results. An objective symptom of motion sickness is facial pallor. It reflects changes in skin microcirculation which have not been measured so far.

Methods:

Eleven healthy volunteers susceptible to motion sickness were subjected to eccentric vertical axis rotation. The dynamics and the correspondence of the changes in skin blood flow in two segments, forehead and finger, were measured by laser Doppler flowmeter.

Results and Conclusions:

The difference in the microcirculatory skin blood flow across the phases of motion sickness is significant for the forehead but not for the fingertip; the established dynamics of the forehead blood flow during motion sickness will be of benefit in quantifying the degree of sickness; there is no correlation between the blood flow changes in both measured areas; the rhythmic blood flow fluctuation increases during motion sickness; there is a difference between the blood flow responses to vestibular stimulation before the appearance of motion sickness and in the course of the sickness. Laser Doppler flowmetry is a reliable method in quantifying the degree of motion sickness.

Résumé:

RÉSUMÉ:Introduction

On doit observer des changements physiologiques pendant le mal des transports (MT) pour pouvoir quantifier le degré de malaise. Une revue de la littérature ne montre pas de résultats uniformes. Un symptôme objectif du mal des transports, qui n'a pas été mesuré à date, est la pâleur faciale qui refléte des changements dans la microcirculation.

Méthodes:

Onze volontaires normaux sensibles au mal des transports ont été soumis à la rotation eccentrique autour d'un axe vertical. Nous avons mesuré la dynamique et la correspondance des changements du flot sanguin cutané dans deux segments, le front et les doigts, au moyen d'un vélocimètre Doppler au laser.

Résultats et Conclusions:

La différence dans le débit sanguin de la microcirculation cutanée pendant toutes les phases du mal des transports est significative au niveau du front mais pas au bout des doigts. La dynamique du débit snaguin au front pendant le mal des transports sera utile pour quantifier le degré de malaise. Il n'existe pas de corrélation entre les changements du débit sanguin dans les deux régions où nous l'avons mesuré. La fluctuation rythmique du débit augmente pendant le mal des transports. Il existe une différence entre les résponses du débit sanguin à la stimulation vestibulaire avant l'apparition du mal des transports et pendant le malaise. La vélocimétrie Doppler au laser est une méthode fiable pour quantifier le degré de mal des transports.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 24 , Issue 1 , February 1997 , pp. 53 - 57
Copyright
Copyright © Canadian Neurological Sciences Federation 1997

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