Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-30T14:57:26.140Z Has data issue: false hasContentIssue false
  • English
  • Français

Relapsing Polychondritis with Multifocal Neurological Abnormalities

Published online by Cambridge University Press:  18 September 2015

J. Willis ,
E.A. Atack  and
G. Kraag
J. Willis
Affiliation:
Division of Neurology, Department of Medicine, Ottawa Civic Hospital and the University of Ottawa Medical School
E.A. Atack*
Affiliation:
Division of Neurology, Department of Medicine, Ottawa Civic Hospital and the University of Ottawa Medical School
G. Kraag
Affiliation:
Division of Neurology, Department of Medicine, Ottawa Civic Hospital and the University of Ottawa Medical School
*
Division of Neurology, Ottawa Civic Hospital D-7, Ottawa, Canada Kl Y 4E9
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A sixty-five year old woman developed relapsing polychondritis with three of the diagnostic criteria established by McAdam et al. (1976), namely bilateral auricular chondritis, ocular inflammation and both cochlear and vestibular dysfunction. Many authors have mentioned other neurological symptoms including unilateral facial weakness. This patient is the first case described with bilateral facial weakness and cerebral manifestations.

Relapsing polychondritis, an uncommon, recurrent, inflammatory disorder affecting the cartilaginous tissues of the body (Jaksch-Wartenhorst, 1923; Herman, 1981), is regularly associated with audiovestibular dysfunction (Bollet et al., 1969; Cody et al., 1971; McAdam et al., 1976; Ridgway et al., 1979). McAdam et al. (1976) and Ridgway et al. (1979) have mentioned other neurological symptoms including unilateral facial weakness. We recently observed a patient with polychondritis and multifocal neurological abnormalities. We believe this is the first case described with bilateral facial nerve palsy and with cerebral manifestations.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 11 , Issue 3 , August 1984 , pp. 402 - 404
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

References

Barranco, V, Minor, D, Solomon, H (1976) Treatment of R.P. with Dapsone. Arch. Dermatol. 112: 1286–1288.CrossRefGoogle Scholar
Bicknell, JM, Holland, JV (1978) Neurologic manifestations of Cogan syndrome. Neurology 28: 278–281.CrossRefGoogle ScholarPubMed
Bollet, A, Smith, J, Mushet, G, Austin, F (1969) Arthritis, Deafness and Saddle Nose. J. Med. Assoc. G.A., 58: 315.Google ScholarPubMed
Cody, D, Jones, D (1971) Relapsing polychondritis: Audio-Vestibular Manifestations, Laryngoscope, 81: 1208.CrossRefGoogle Scholar
Dolan, D, Lemmon, G, Teitelbaum, S (1966) Relapsing Polychondritis Analytical Literature Review Am. J. Med. 41: 285.CrossRefGoogle Scholar
Herman, J (1981) Relapsing Polychondritis Textbook of Rheumatology, William N. Kelly et al., Vol. 2: 1500–8.Google Scholar
Hughes, R, Berry, C, Seifert, M (1972) Relapsing Polychondritis: Clinicopathological Study and Literature Review. Q.J. Med., 61: 363.Google Scholar
Jacksch-Wartenhorst, J, (1923) Polychondropathia. Arch. Intern. Med. 6: 93–100.Google Scholar
Kaye, R, Jones, D (1964) R.P. Clinical and Pathological Features in 14 cases. Ann. Intern. Med., 60: 653.CrossRefGoogle Scholar
Martin, J, Roenick, H, Lynch, W (1976) R.P. Treated with Dapsone. Arch. Dermatol. 112: 1272–1274.CrossRefGoogle Scholar
McAdam, L, O’Hanlan, M, Bluestone, R, Pearson, C (1976) Relapsing Polychondritis: Prospective Study of 23 Patients. Medicine, 55: 193–215.CrossRefGoogle ScholarPubMed
Ridgway, H, Hansotia, D, Schorr, W (1979) Relapsing Polychondritis: Unusual Neurological Findings and Therapeutic Efficacy of Dapsone. Arch. Dermatol., 115: 43–45.CrossRefGoogle ScholarPubMed