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Prolactin-Secreting Adenomas - Surgical Results

Published online by Cambridge University Press:  18 September 2015

Giulio Maira ,
Carmelo Anile ,
Laura De Marinis  and
Antonino Barbarino
Giulio Maira*
Affiliation:
Institute of Neurosurgery, Catholic University, Rome, Italy
Carmelo Anile
Affiliation:
Institute of Neurosurgery, Catholic University, Rome, Italy
Laura De Marinis
Affiliation:
Institute of Endocrinology, Catholic University, Rome, Italy
Antonino Barbarino
Affiliation:
Institute of Endocrinology, Catholic University, Rome, Italy
*
Istituto di Neurochirurgia, Policlinico Gemelli, Largo Gemelli 8, 00168 Roma, Italia
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Abstract:

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The long-term follow-up of the transsphenoidal microsurgical treatment in 119 consecutively operated women with a PRL-secreting adenoma is presented. An apparent total removal of the tumor was achieved in 98 cases with an enclosed tumor (58 grade I and 40 grade II). In the remaining cases the removal was considered partial. The achievement of persistent normal PRL basal levels was verified in 61 patients (44 grade I and 17 grade II) who had an apparent total removal of the adenoma. In the 37 remaining patients who were thought at surgery to have had total removal we have distinguished two groups: 30 patients showed a “relapse” or “persistence” of PRL levels below 200 ng/ml without clinical and radiological signs of tumor regrowth, and 7 patients with a PRL level higher than 200 ng/ml who had evidence of PRL-secreting tumor recurrence.

Type
Special Supplement - Secreting Pituitary Adenomas
Information
Canadian Journal of Neurological Sciences , Volume 17 , Issue 1 , February 1990 , pp. 67 - 70
Copyright
Copyright © Canadian Neurological Sciences Federation 1990

References

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