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Principles Underlying New Methods for Chronic Neural Recording

Published online by Cambridge University Press:  18 September 2015

R.B. Stein ,
D. Charles ,
L. Davis ,
J. Jhamandas ,
A. Mannard  and
T.R. Nichols
R.B. Stein*
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
D. Charles
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
L. Davis
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
J. Jhamandas
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
A. Mannard
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
T.R. Nichols
Affiliation:
Departments of Physiology and Surgery, University of Alberta, Edmonton
*
Dept. of Physiology, Medical Science Bldg., University of Alberta, Edmonton, Canada T6G 2E1
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Chronic recording is possible from nerve fibers which have grown through holes in an insulating medium (regeneration electrodes) or which are enclosed by an insulating sheath (cuff electrodes). Use of three electrodes in a balanced configuration permits good rejection of electromyographic (EMG) signals and other sources of electrical interference (fluorescent lights, 60 Hz signals from the mains, etc.). Equations are derived and tested for predicting the amplitude and form of the signals expected for a given cuff length and diameter. These equations can be used to design electrode units optimally for a given application. Finally, the use of transformers permits the neural signals to be carefully matched to the recording apparatus and further optimizes the neural signal-to-noise and signal-to-EMG ratios. Use of these methods in several physiological and clinical applications, as well as potential abuses, are discussed.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 2 , Issue 3 , August 1975 , pp. 235 - 244
Copyright
Copyright © Canadian Neurological Sciences Federation 1975

References

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