Hostname: page-component-745bb68f8f-v2bm5 Total loading time: 0 Render date: 2025-01-21T23:41:33.789Z Has data issue: false hasContentIssue false
  • English
  • Français

Primary Spontaneous Mesencephalic Hemorrhage

Published online by Cambridge University Press:  18 September 2015

Mark F. Mehler  and
Philip S. Ragone
Mark F. Mehler*
Affiliation:
Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, U.S.A. and the Neurological Services, Bronx Municipal Hospital Center, Montefiore Hospital Medical Center and J.D. Weiler Hospital of the Albert Einstein College of Medicine
Philip S. Ragone
Affiliation:
Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, U.S.A. and the Neurological Services, Bronx Municipal Hospital Center, Montefiore Hospital Medical Center and J.D. Weiler Hospital of the Albert Einstein College of Medicine
*
Department of Neurology (F, G-9), Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, U.S.A. 10461
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The case histories of two patients with clinically diverse forms of the very rare entity primary, spontaneous mesencephalic hemorrhage are presented. Each exhibited characteristic mesencephalic signs and neuroimaging profiles. However, both patients differed markedly in their predisposing factors, state of arousal, memory, temporal course and functional residua. One patient was unique in displaying a normal level of alertness throughout his clinical course and an isolated retrograde amnesia. The latter sign suggests a role for mesencephalic reticular activation in long-term retrieval and illustrates the differential effects of a subtle activation deficit on memory and arousal. These findings broaden the distinctive clinico-anatomical profile of primary, spontaneous mesencephalic hemorrhage.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 15 , Issue 4 , November 1988 , pp. 435 - 438
Copyright
Copyright © Canadian Neurological Sciences Federation 1988

References

REFERENCES

1.Durward, QJ, Barnett, HJM, Barr, HWK. Presentation and management of mesencephalic hematoma. J Neurosurg 1982; 56: 123–127.CrossRefGoogle ScholarPubMed
2.Humphreys, RP. Computerized tomographic definition of mesencephalic hematoma with evacuation through pedunculotomy. J Neurosurg 1978; 49: 749–752.CrossRefGoogle ScholarPubMed
3.LaTorre, E, Delitala, A, Sorano, V. Hematoma of the quadrigeminal plate. J Neurosurg 1978; 49: 610–613.Google Scholar
4.Morel-Maroger, A, Metzger, J, Bories, J, et al. Les hématomes bénins du tronc cérébral chez les hypertendus artériels. Rev Neurol (Paris) 1982; 138: 437–445.Google Scholar
5.Roig, C, Carvajal, A, Illa, I, et al. Hémorragies mesencéphaliquesisolées. Trois cas diagnostiques par tomodensitométrie. Rev Neurol (Paris) 1982; 138:53–61.Google Scholar
6.Scoville, WB, Poppen, JL. Intrapeduncular hemorrhage of the brain. Arch Neurol Psychiatry 1949; 61: 688–694.CrossRefGoogle ScholarPubMed
7.Weisberg, LA. Mesencephalic hemorrhages: clinical and computed tomographic correlations. Neurology 1986; 36: 713–716.CrossRefGoogle ScholarPubMed
8.van Gijn, J, van Dongen, KJ, Vermuelen, M, et al. Perimesencephalic hemorrhage: A nonaneurysmal and benign form of subarachnoid hemorrhage. Neurology 1985; 35: 493–497.CrossRefGoogle ScholarPubMed
9.Buschke, H, Fuld, PA. Evaluating storage, retention and retrieval in disordered memory and learning. Neurology 1974; 24: 1019–1024.CrossRefGoogle ScholarPubMed
10.Albert, MS, Butters, N, Levin, J. Temporal gradient in the retrograde amnesia of patients with alcoholic Korsakoff’s disease. Arch Neurol 1979; 36: 211–216.CrossRefGoogle ScholarPubMed
11.Caplan, LR. “Top of the basilar” syndrome. Neurology 1980; 30: 72–79.CrossRefGoogle ScholarPubMed
12.Mehler, MF. Reversible rostral basilar artery syndrome. Arch Int Med 1988; 148: 166–169.CrossRefGoogle ScholarPubMed
13.Miller, NR. Walsh and Hoyt’s Clinical Neuro-ophthalmology, Vol. 2. Baltimore: Williams and Wilkins, 1985; 716–719.Google Scholar
14.Brandt, T, Dieterich, M. Pathological eye-head coordination in roll: Tonic ocular tilt reaction in mesencephalic and medullary lesions. Brain 1987; 110: 649–666.CrossRefGoogle ScholarPubMed
15.Goldberg, E, Antin, S, Bilder, RM, et al. Retrograde amnesia: Possible role of mesencephalic reticular activation in long-term memory. Science 1981; 213: 1392–1394.CrossRefGoogle ScholarPubMed
16.Bogousslavsky, J, Meienberg, O. Eye-movement disorders in brain-stem and cerebellar stroke. Arch Neurol 1987; 44: 141–148.CrossRefGoogle ScholarPubMed
17.Plum, F, Posner, JB. The diagnosis of stupor and coma. Philadelphia: F.A. Davis and Co, 1980; 167.Google Scholar
18.Barraquer-Bordas, L, Illa, I, Escartin, A, et al. Thalamic hemorrhage: A study of 23 patients with a diagnosis by computed tomography. Stroke 1981; 12: 524–527.CrossRefGoogle ScholarPubMed
19.Kwak, R, Kadoya, S, Suzuki, T. Factors affecting prognosis in thala-mic hemorrhage. Stroke 1983; 14: 493–500.CrossRefGoogle ScholarPubMed
20.Piepgras, U, Rieger, P. Thalamic bleeding: diagnosis, course, prog-nosis. Neuroradiology 1981; 22: 85–91.CrossRefGoogle Scholar
21.Walshe, TM, David, KR, Fisher, CM. Thalamic hemorrhage: A computed tomographic-clinical correlation. Neurology 1977; 27: 217–222.CrossRefGoogle ScholarPubMed
22.Lhermitte, J. Les hémorragies des pédoncules cérébraux: étude clinique. Presse Med 1942; 45: 625–626.Google Scholar